Single-cell and spatial profiling reveal cDC2A-CXCL13(+)CD8(+) T-epithelial cell crosstalk and cytotoxicity through TNFRSF9 in cutaneous and mucosal lichen planus
单细胞和空间分析揭示了皮肤和黏膜扁平苔藓中 cDC2A-CXCL13(+)CD8(+) T 上皮细胞通过 TNFRSF9 进行串扰和细胞毒性
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70506-z
Jiang, Rundong; Bogle, Rachael; Xing, Xianying; Kirma, Joseph; Fox, Jennifer; Harms, Paul W; Do, Tran; Billi, Allison C; Kahlenberg, J Michelle; Modlin, Robert L; Teles, Rosane; West, Julie; Mangold, Aaron; Zhang, Haihan; Schneider, Martin A; Bruno, Sandro; Roediger, Ben; Martiny-Baron, Georg; Tsoi, Lam C; Hacini-Rachinel, Feriel; Röhn, Till A; Gudjonsson, Johann E
单细胞
CD8
毒理研究
CXCL13
细胞生物学
TNFRSF9
CXCL1
上皮细胞
T细胞