TRPM5相关文献与解析，生知库 | 链接生命科学的每一步

Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis

内源性肽CBDP1通过靶向USP5/YTHDF2/TRPM5轴抑制透明细胞肾细胞癌的进展。

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-06091-4

Zhang, Yang; Zhu, Wei; Tao, Ruijie; Li, Weijian; Jiang, Chunming; Yan, Xiang

Estrogen-Dependent Variation in the Contributions of TRPM4 and TRPM5 to Fat Taste

雌激素依赖性TRPM4和TRPM5对脂肪味觉贡献的变化

期刊:Nutrients

影响因子:5

doi:10.3390/nu17243847

Masterson, Emeline; Dahir, Naima S; Calder, Ashley N; Liu, Yan; Lin, Fangjun; Gilbertson, Timothy A

The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5-Independent Manner

TRPM5拮抗剂三苯基氧化膦以不依赖于TRPM5的方式增加皮脂生成并调节人类皮脂细胞的免疫表型

期刊:Experimental Dermatology

影响因子:3.5

doi:10.1111/exd.70115

Dorottya Ádám ,József Arany ,Kinga Fanni Tóth ,Orsolya Pető ,Tamara Nyitrai ,Balázs István Tóth ,Szilárd Póliska ,Christos C Zouboulis ,Attila Oláh

β-Adrenergic Blockers Increase cAMP and Stimulate Insulin Secretion Through a PKA/RYR2/TRPM5 Pathway in Pancreatic β-Cells In Vitro

β-肾上腺素能阻滞剂通过PKA/RYR2/TRPM5通路增加胰岛β细胞中的cAMP并刺激胰岛素分泌（体外实验）

期刊:Pharmacology Research & Perspectives

影响因子:2.9

doi:10.1002/prp2.70092

Naoya Murao,Risa Morikawa,Yusuke Seino,Kenju Shimomura,Yuko Maejima,Yuichiro Yamada,Atsushi Suzuki

Estrogen Dependent Variation in the Contributions of TRPM4 and TRPM5 to Fat Taste

雌激素依赖性TRPM4和TRPM5对脂肪味觉贡献的变化

期刊:

影响因子:

doi:10.1101/2025.11.05.686796

Masterson, Emeline; Dahir, Naima S; Calder, Ashley N; Liu, Yan; Lin, Fangjun; Gilbertson, Timothy A

Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel

胞质内亚基间界面处的结构动力学控制哺乳动物TRPM5通道的门控

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2403333121

Karuppan, Sebastian; Schrag, Lynn Goss; Pastrano, Caroline M; Jara-Oseguera, Andrés; Zubcevic, Lejla

TRPM5

发表日期：2024

文献求助收藏

A hydrophobic funnel governs monovalent cation selectivity in the ion channel TRPM5

疏水漏斗控制着离子通道TRPM5中单价阳离子的选择性。

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2024.07.035

Ives, Callum M; Şahin, Alp Tegin; Thomson, Neil J; Zachariae, Ulrich

TRPM5

发表日期：2024

文献求助收藏

Dietary experience with glucose and fructose fosters heightened avidity for glucose-containing sugars independent of TRPM5 taste transduction in mice

小鼠摄入葡萄糖和果糖后，对含葡萄糖糖类的偏好性增强，而这种偏好性与TRPM5味觉转导无关。

期刊:Nutritional Neuroscience

影响因子:3.6

doi:10.1080/1028415X.2022.2050092

Ascencio Gutierrez, Verenice; Simental Ramos, Aracely; Khayoyan, Shushanna; Schier, Lindsey A

Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition

TRPM5通道的结构阐明了其激活和抑制机制。

期刊:Nature Structural & Molecular Biology

影响因子:10.1

doi:10.1038/s41594-021-00607-4

Ruan, Zheng; Haley, Emery; Orozco, Ian J; Sabat, Mark; Myers, Richard; Roth, Rebecca; Du, Juan; Lü, Wei

TRPM5

发表日期：2021

文献求助收藏

A single allosteric site merges activation, modulation and inhibition in TRPM5

TRPM5 中单个变构位点集激活、调节和抑制功能于一体。

Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis

内源性肽CBDP1通过靶向USP5/YTHDF2/TRPM5轴抑制透明细胞肾细胞癌的进展。

Estrogen-Dependent Variation in the Contributions of TRPM4 and TRPM5 to Fat Taste

雌激素依赖性TRPM4和TRPM5对脂肪味觉贡献的变化

The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5-Independent Manner

TRPM5拮抗剂三苯基氧化膦以不依赖于TRPM5的方式增加皮脂生成并调节人类皮脂细胞的免疫表型

β-Adrenergic Blockers Increase cAMP and Stimulate Insulin Secretion Through a PKA/RYR2/TRPM5 Pathway in Pancreatic β-Cells In Vitro

β-肾上腺素能阻滞剂通过PKA/RYR2/TRPM5通路增加胰岛β细胞中的cAMP并刺激胰岛素分泌（体外实验）

Estrogen Dependent Variation in the Contributions of TRPM4 and TRPM5 to Fat Taste

雌激素依赖性TRPM4和TRPM5对脂肪味觉贡献的变化

Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel

胞质内亚基间界面处的结构动力学控制哺乳动物TRPM5通道的门控

A hydrophobic funnel governs monovalent cation selectivity in the ion channel TRPM5

疏水漏斗控制着离子通道TRPM5中单价阳离子的选择性。

Dietary experience with glucose and fructose fosters heightened avidity for glucose-containing sugars independent of TRPM5 taste transduction in mice

小鼠摄入葡萄糖和果糖后，对含葡萄糖糖类的偏好性增强，而这种偏好性与TRPM5味觉转导无关。

Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition

TRPM5通道的结构阐明了其激活和抑制机制。