TRPM8相关文献与解析，生知库 | 链接生命科学的每一步

Dietary Caffeine, Cold Exposure, and the Estrogen-TRPM8 Axis: A Nutri-Environmental Model for Lower Urinary Tract Symptoms in the Menopause Transition: A Narrative Review

膳食咖啡因、寒冷刺激和雌激素-TRPM8轴：更年期过渡期下尿路症状的营养-环境模型：叙述性综述

期刊:Nutrients

影响因子:5

doi:10.3390/nu18050825

Lee, Dong Hee; Park, Jeong Jun

Prefrontal TRPM8 Receptor Modulates Epileptic Seizures via PKA/CREB Signaling Pathway in Mice.

小鼠前额叶TRPM8受体通过PKA/CREB信号通路调节癫痫发作。

期刊:CNS Neuroscience & Therapeutics

影响因子:5

doi:10.1002/cns.70709

Huang Jia-Zhan, Lu Gui-Feng, Jiang Yi-Han, Guo Yao, Lin Ze-Yu, Zhang Zhi, Geng Fei

Suppression of neuropathic pain hypersensitivity by TRPM8 is mediated by mGluR group II and III receptors acting differentially on distinct nociceptor inputs to spinal cord

TRPM8通过mGluR II和III组受体对脊髓不同伤害感受器输入发挥差异性作用，从而抑制神经性疼痛过敏。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2026.1806325

Mitchell, Rory; Sun, Liting; Czapranska, Marta; Fleetwood-Walker, Sue

Engineered CGRP Eye Drops Restore Tear Secretion via TRPM8-SSN Circuitry in a Postrefractive Surgery Mouse Model.

工程化 CGRP 眼药水通过 TRPM8-SSN 回路在屈光手术后小鼠模型中恢复泪液分泌。

期刊:Investigative Ophthalmology & Visual Science

影响因子:4.7

doi:10.1167/iovs.67.1.45

TRPM8 Regulates Mitochondrial Ca(2+)-Dynamics, Temperature and Endoplasmic Reticulum-Mitochondrial Contact Points in T Cell

TRPM8 调控 T 细胞线粒体 Ca(2+) 动态、温度和内质网-线粒体接触点

期刊:Journal of Cellular and Molecular Medicine

影响因子:4.2

doi:10.1111/jcmm.71014

Acharya, Tusar Kanta; Kumar, Shamit; Rokade, Tejas Pravin; Mahapatra, Parnasree; Chang, Young Tae; Goswami, Chandan

Nano-icilin-driven TRPM8 activation elicits immunogenic exosomes with antitumor effects.

纳米冰片驱动的 TRPM8 激活可诱导产生具有抗肿瘤作用的免疫原性外泌体。

期刊:Nanomedicine

影响因子:3.9

doi:10.1080/17435889.2025.2583209

Noorkhajavi Ghasem, Hemmati Salar, Shahgolzari Mehdi, Fiering Steven, Yari Khosroushahi Ahmad

Plant-Derived Secondary Metabolites Tetrahydropalmatine and Rutaecarpine Alleviate Paclitaxel-Induced Neuropathic Pain via TRPV1 and TRPM8 Modulation

植物来源的次生代谢产物四氢巴马汀和芸香碱通过调节TRPV1和TRPM8缓解紫杉醇诱导的神经性疼痛

期刊:Metabolites

影响因子:3.7

doi:10.3390/metabo16010046

Park, Keun-Tae; Yun, Hyesang; Kang, Juyeol; Lee, Jae-Chul; Kim, Woojin

HPLC Purification of TRPM8 and Experimental Confirmation of Its Cholesterol Affinity on Synthetic Lipid Raft-like Models

TRPM8的HPLC纯化及其在合成脂筏样模型上对胆固醇亲和力的实验验证

期刊:Life-Basel

影响因子:3.4

doi:10.3390/life16030392

Angelucci, Clotilde Beatrice; Sabatucci, Annalaura; Kurtz, Alexandrine; Laurenti, Davide; Dufrusine, Beatrice; Dainese, Enrico; Francioso, Antonio

Pharmacological Blockade of TRPM8 Ion Channels Fails to Reduce Behavioral and Biological Markers of Acute Oral Pain in Irradiated C57BL/6J Mice

TRPM8离子通道的药理学阻断未能降低受辐射C57BL/6J小鼠急性口腔疼痛的行为和生物学标志物

期刊:Radiation Research

影响因子:2.7

doi:10.1667/RADE-25-00026.1

Wheeler, Joshua J; Ingkasri, Thitsana; Lai, Yen-Hao; Jones, Jaylen; Marcus, Karen L; Schofield, Sophi J; Roback, Donald M; Mowery, Yvonne M; Lascelles, B Duncan X; Mishra, Santosh K; Nolan, Michael W

TRPM8

发表日期：2026

文献求助收藏

Rewiring melanoma cell fate: TRPM8 modulators trigger apoptosis and boost NK cell cytotoxicity.

重塑黑色素瘤细胞命运：TRPM8 调节剂触发细胞凋亡并增强 NK 细胞的细胞毒性。

Dietary Caffeine, Cold Exposure, and the Estrogen-TRPM8 Axis: A Nutri-Environmental Model for Lower Urinary Tract Symptoms in the Menopause Transition: A Narrative Review

膳食咖啡因、寒冷刺激和雌激素-TRPM8轴：更年期过渡期下尿路症状的营养-环境模型：叙述性综述

Prefrontal TRPM8 Receptor Modulates Epileptic Seizures via PKA/CREB Signaling Pathway in Mice.

小鼠前额叶TRPM8受体通过PKA/CREB信号通路调节癫痫发作。

Suppression of neuropathic pain hypersensitivity by TRPM8 is mediated by mGluR group II and III receptors acting differentially on distinct nociceptor inputs to spinal cord

TRPM8通过mGluR II和III组受体对脊髓不同伤害感受器输入发挥差异性作用，从而抑制神经性疼痛过敏。

Engineered CGRP Eye Drops Restore Tear Secretion via TRPM8-SSN Circuitry in a Postrefractive Surgery Mouse Model.

工程化 CGRP 眼药水通过 TRPM8-SSN 回路在屈光手术后小鼠模型中恢复泪液分泌。

TRPM8 Regulates Mitochondrial Ca(2+)-Dynamics, Temperature and Endoplasmic Reticulum-Mitochondrial Contact Points in T Cell

TRPM8 调控 T 细胞线粒体 Ca(2+) 动态、温度和内质网-线粒体接触点

Nano-icilin-driven TRPM8 activation elicits immunogenic exosomes with antitumor effects.

纳米冰片驱动的 TRPM8 激活可诱导产生具有抗肿瘤作用的免疫原性外泌体。

Plant-Derived Secondary Metabolites Tetrahydropalmatine and Rutaecarpine Alleviate Paclitaxel-Induced Neuropathic Pain via TRPV1 and TRPM8 Modulation

植物来源的次生代谢产物四氢巴马汀和芸香碱通过调节TRPV1和TRPM8缓解紫杉醇诱导的神经性疼痛

HPLC Purification of TRPM8 and Experimental Confirmation of Its Cholesterol Affinity on Synthetic Lipid Raft-like Models

TRPM8的HPLC纯化及其在合成脂筏样模型上对胆固醇亲和力的实验验证

Pharmacological Blockade of TRPM8 Ion Channels Fails to Reduce Behavioral and Biological Markers of Acute Oral Pain in Irradiated C57BL/6J Mice

TRPM8离子通道的药理学阻断未能降低受辐射C57BL/6J小鼠急性口腔疼痛的行为和生物学标志物