日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

CM512, a potentially novel IgG1-based bispecific antibody dual-targeting TSLP and IL-13, for the suppression of type 2 inflammation

CM512 是一种潜在的新型 IgG1 类双特异性抗体，可同时靶向 TSLP 和 IL-13，用于抑制 2 型炎症。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-026-08012-5
Yang, Yunxiao; Lan, Yuzhen; Bian, Linxi; Li, Yufei; Song, Qin; Gao, Xinmei; Hou, Qiaoyun; Bai, Yundan; Chen, Bo
炎症
炎症/感染
CM5
IgG
IL-13
TSLP
发表日期：2026
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Enhanced Alarmin Secretion Exacerbates Neutrophil Extracellular Trap (NET) Formation in Active Psoriasis: Implication of IL-33 and TSLP in Driving NET Formation, Inflammation and Oxidative Stress in Psoriasis

增强的报警素分泌加剧了活动性银屑病中中性粒细胞胞外陷阱（NET）的形成：IL-33和TSLP在驱动银屑病NET形成、炎症和氧化应激中的作用

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox15010071
Ojha, Vanshika; Tembhre, Manoj Kumar; Gupta, Vishal
IL-3
IL-33
炎症
中性粒细胞
氧化应激
炎症/感染
Immunology/Inflammation
银屑病
粒细胞
TSLP
细胞生物学
毒理研究
发表日期：2026
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Beyond inhaled medications: precision medicine and biologic therapies targeting the IL-33/TSLP/type 2 axis in COPD

除吸入药物外：针对慢性阻塞性肺疾病中IL-33/TSLP/2型轴的精准医疗和生物疗法

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1772031
Song, Guo-Qiang; Chen, Bangsheng; He, Tian-Li; Hu, Guo-Qiang
IL-33
IL-3
TSLP
慢性阻塞性肺疾病
发表日期：2026
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Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32-Week Randomized Phase 1b Multiple Ascending-Dose Trial

Verekitug，一种新型的TSLP受体抗体拮抗剂，用于治疗成人哮喘：一项为期32周的随机1b期多剂量递增试验

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.70156
Singh, Dave; Brickman, Chaim M; Lloyd, Peter; Kalra, Ashish; Biswas, Subhabrata; Sinha, Arkadeep; Mulvanny, Alex; Sivapalasingam, Sumathi; Becker, Oren M; Deykin, Aaron
信号转导
哮喘
TSLP
发表日期：2026
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Safety, Tolerability, and Pharmacokinetics of HBM9378 (SKB378/WIN378), a Fully Human IgG1 Monoclonal Antibody Against TSLP After Single Ascending Doses in Chinese Healthy Subjects

HBM9378 (SKB378/WIN378)（一种全人源抗TSLP IgG1单克隆抗体）在中国健康受试者中单次递增剂量给药后的安全性、耐受性和药代动力学研究

期刊:Drug Design Development and Therapy
影响因子:5.1
doi:10.2147/DDDT.S538649
Yang, Xiaojia; Xu, Min; Cao, Nan; Zhao, Shuai; Wei, Yuanqing; Lu, Jia; Luo, Ruixuan; Ge, Junyou; Tao, Xiaolu; He, Wen
单克隆抗体
IgG
TSLP
Human
发表日期：2026
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QX008N, an Anti-TSLP Monoclonal Antibody: Pharmacokinetics, Tolerability, and Immunogenicity in Healthy Chinese Subjects

QX008N，一种抗TSLP单克隆抗体：在中国健康受试者中的药代动力学、耐受性和免疫原性

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.70473
Shen, Zhen-Wei; Jiang, Qi; Wu, Kai-Qi; Jin, Ting-Han; Zhao, Jie; Guo, Tong; Fang, Min; Chen, Gui-Ling
单克隆抗体
TSLP
免疫/内分泌
发表日期：2026
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The predictive value of combined detection of serum IL-33, TSLP and eosinophils in the treatment effect and exacerbation risk of chronic obstructive pulmonary disease

血清IL-33、TSLP和嗜酸性粒细胞联合检测对慢性阻塞性肺疾病治疗效果和病情加重风险的预测价值

期刊:BMC Pulmonary Medicine
影响因子:2.8
doi:10.1186/s12890-026-04144-y
Xu, Jie; Wang, Yong; Gu, Haitong; Chen, Xiao
IL-3
IL-33
慢性阻塞性肺疾病
粒细胞
TSLP
细胞生物学
发表日期：2026
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Dupilumab attenuates the expression of TSLP and IL-8 induced by dsRNA and IL-4/IL-13 co-stimulation in human small airway epithelial cells

Dupilumab可减弱dsRNA和IL-4/IL-13共刺激诱导的人小气道上皮细胞中TSLP和IL-8的表达。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0341562
Sri Listyoko, Aditya; Okazaki, Ryota; Harada, Tomoya; Inui, Genki; Kohno, Hiroki; Nishigami, Miyu; Takata, Miki; Morita, Masato; Yamasaki, Akira
上皮细胞
IL-8
TSLP
IL-13
细胞生物学
IL-4
发表日期：2026
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Retraction: Effects of microRNA-19b on airway remodeling, airway inflammation and degree of oxidative stress by targeting TSLP through the Stat3 signaling pathway in a mouse model of asthma

撤稿：microRNA-19b通过Stat3信号通路靶向TSLP，对哮喘小鼠模型气道重塑、气道炎症和氧化应激程度的影响

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.28841
Ye, Ling; Mou, Yan; Wang, Jian; Jin, Mei-Ling
哮喘
炎症
氧化应激
炎症/感染
信号转导
TSLP
毒理研究
发表日期：2026
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TSLP links intestinal nutrient sensing with amplification of the ILC2-tuft cell circuit

TSLP 将肠道营养感知与 ILC2-簇状细胞回路的放大联系起来

期刊:Nature Immunology
影响因子:27.7
doi:10.1038/s41590-025-02328-y
Chang Liao ，Elvira Mennillo ，Michael G Kattah ，Ming Ji ，Zhi-En Wang ，Daniel J Drucker ，Hong-Erh Liang ，Richard M Locksley
TSLP
发表日期：2025
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