U2AF1相关文献与解析，生知库 | 链接生命科学的每一步

Splice-site mutations in POU2AF1 are associated with B-cell lymphomagenesis and therapeutic response

POU2AF1 剪接位点突变与 B 细胞淋巴瘤的发生和治疗反应相关

Yanguas-Casás, Natalia; Pedrosa, Lucía; Horcajo, Beatriz; Gómez, Sagrario; Garcia-Grande, Aranzazu; Muñoz-Viana, Rafael; Fernández-Miranda, Ismael; Pérez-Aguilera, Marina; Torres-Ruiz, Raúl; Rodríguez-Perales, Sandra; Sánchez-Beato, Margarita

淋巴瘤

Phosphorylation-dependent regulation of serine/arginine-rich proteins and U2AF1 interactions in early spliceosome assembly

丝氨酸/精氨酸富集蛋白和U2AF1相互作用的磷酸化依赖性调控在早期剪接体组装中的作用

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2026.111222

Zhang, Zihan; Kunwar, Puspa; Yu, Yanbao; Prevelige, Peter; Zhang, Jun

Rapid Development of Unclassified Myeloid Lineage Acute Leukaemia With Trisomy 6 and U2AF1 Mutation

伴有6号染色体三体和U2AF1突变的未分类髓系急性白血病的快速发展

期刊:Journal of Cellular and Molecular Medicine

影响因子:4.2

doi:10.1111/jcmm.70461

Markiewicz, Miroslaw; Kopacz, Agnieszka; Blajer-Olszewska, Beata; Mazur, Malwina; Warzybok, Katarzyna; Szarawarska, Marta; Wojtaszewska, Marzena; Moskwa, Monika; Dudycz, Dominika; Schwarz, Ewa; Kosior, Katarzyna; Lewandowski, Krzysztof

Discovery of the U2AF1-UHM Inhibitor That Possesses Anti-Leukemia Activity In Vitro

发现具有体外抗白血病活性的U2AF1-UHM抑制剂

期刊:ACS Medicinal Chemistry Letters

影响因子:4

doi:10.1021/acsmedchemlett.5c00424

Patil, Amol D; Kazemi Sabzvar, Mona; Yuan, Xinrui; Collier, Daniel M; Yang, Chao-Yie

Revealing the role of U2AF1 in splicing regulation and chimeric RNA dynamics

揭示U2AF1在剪接调控和嵌合RNA动力学中的作用

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-99865-1

Khan, Sangeen; Tang, Yue; Guo, Yangyang; Feng, Jing; Wu, Hui; Song, Zhenguo; Zhang, Chengjuan; Qin, Fujun

Mutational Spectrum and Clinical Outcomes of Myelodysplastic/Myeloproliferative Neoplasms: A Single-Institution Study in Korea with Emphasis on U2AF1

骨髓增生异常/骨髓增殖性肿瘤的突变谱和临床结局：韩国单中心研究，重点关注U2AF1

期刊:Journal of Clinical Medicine

影响因子:2.9

doi:10.3390/jcm14197074

Park, Min-Seung; Choi, Dae-Ho; Jang, Jun Ho; Jung, Chul Won; Kim, Hee-Jin; Kim, Hyun-Young

Intramedullary erythrophagocytosis in myelodysplastic syndrome with heterozygous U2AF1 Q157R variant

骨髓增生异常综合征伴杂合子 U2AF1 Q157R 变异体中的髓内红细胞吞噬症

期刊:eJHaem

影响因子:1.2

doi:10.1002/jha2.1084

Krishnamurthy, Kritika; Shastri, Aditi; Wang, Yanhua

Dyskeratosis Congenita Complicated by Pulmonary Fibrosis and Myelodysplastic Syndrome with a Germline Mutation of the DKC1 Gene and a Somatic Mutation of the U2AF1 Gene in Leukocytes

先天性角化不良合并肺纤维化和骨髓增生异常综合征，伴有DKC1基因种系突变和白细胞U2AF1基因体细胞突变

期刊:Internal Medicine

影响因子:1.1

doi:10.2169/internalmedicine.5153-24

Watanabe, Hiroko; Takahashi, Yuta; Namiki, Tomohiro; Nakagawa, Ryusei; Inui, Toshihide; Ishikawa, Hiroaki; Wakamatsu, Manabu; Muramatsu, Hideki; Sakamoto, Tohru

Global analysis of binding sites of U2AF1 and ZRSR2 reveals RNA elements required for mutually exclusive splicing by the U2- and U12-type spliceosome

U2AF1 和 ZRSR2 结合位点的整体分析揭示了 U2 型和 U12 型剪接体相互排斥剪接所需的 RNA 元素

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkad1180

Young-Soo Kwon, Sang Woo Jin, Hoseok Song

U2AF1

发表日期：2024

文献求助收藏

BCAA catabolism mediates POU2AF1 propionylation to enhance T-ALL development.

BCAA 分解代谢介导 POU2AF1 丙酰化，从而增强 T-ALL 的发展。

Splice-site mutations in POU2AF1 are associated with B-cell lymphomagenesis and therapeutic response

POU2AF1 剪接位点突变与 B 细胞淋巴瘤的发生和治疗反应相关

Phosphorylation-dependent regulation of serine/arginine-rich proteins and U2AF1 interactions in early spliceosome assembly

丝氨酸/精氨酸富集蛋白和U2AF1相互作用的磷酸化依赖性调控在早期剪接体组装中的作用

Rapid Development of Unclassified Myeloid Lineage Acute Leukaemia With Trisomy 6 and U2AF1 Mutation

伴有6号染色体三体和U2AF1突变的未分类髓系急性白血病的快速发展

Discovery of the U2AF1-UHM Inhibitor That Possesses Anti-Leukemia Activity In Vitro

发现具有体外抗白血病活性的U2AF1-UHM抑制剂

Revealing the role of U2AF1 in splicing regulation and chimeric RNA dynamics

揭示U2AF1在剪接调控和嵌合RNA动力学中的作用

Mutational Spectrum and Clinical Outcomes of Myelodysplastic/Myeloproliferative Neoplasms: A Single-Institution Study in Korea with Emphasis on U2AF1

骨髓增生异常/骨髓增殖性肿瘤的突变谱和临床结局：韩国单中心研究，重点关注U2AF1

Intramedullary erythrophagocytosis in myelodysplastic syndrome with heterozygous U2AF1 Q157R variant

骨髓增生异常综合征伴杂合子 U2AF1 Q157R 变异体中的髓内红细胞吞噬症

Dyskeratosis Congenita Complicated by Pulmonary Fibrosis and Myelodysplastic Syndrome with a Germline Mutation of the DKC1 Gene and a Somatic Mutation of the U2AF1 Gene in Leukocytes

先天性角化不良合并肺纤维化和骨髓增生异常综合征，伴有DKC1基因种系突变和白细胞U2AF1基因体细胞突变

Global analysis of binding sites of U2AF1 and ZRSR2 reveals RNA elements required for mutually exclusive splicing by the U2- and U12-type spliceosome

U2AF1 和 ZRSR2 结合位点的整体分析揭示了 U2 型和 U12 型剪接体相互排斥剪接所需的 RNA 元素