U2AF2相关文献与解析，生知库 | 链接生命科学的每一步

Vascular smooth muscle cell RNA-binding protein U2AF2 induces copper death by regulating C1qbp expression, delaying development of atherosclerosise.

血管平滑肌细胞 RNA 结合蛋白 U2AF2 通过调节 C1qbp 表达诱导铜死亡，延缓动脉粥样硬化的发展。

期刊:Biological Research

影响因子:4.6

doi:10.1186/s40659-026-00672-3

SF3B1 Phosphorylation Prompts U2AF2 Dissociation for Widespread Control of pre-mRNA Splicing

SF3B1磷酸化促进U2AF2解离，从而广泛调控前体mRNA剪接

期刊:

影响因子:

doi:10.64898/2026.01.19.700466

Kirchhoff, Christopher L; Powell, Hannah R; Galardi, Justin W; Loerch, Sarah; Pulvino, Mary J; Jenkins, Jermaine L; Boutz, Paul L; Kielkopf, Clara L

HPGD induces ferroptosis and autophagy to suppress esophageal squamous cell carcinoma through the LXA4-ERK1/2-U2AF2-TFRC axis

HPGD通过LXA4-ERK1/2-U2AF2-TFRC轴诱导铁死亡和自噬，从而抑制食管鳞状细胞癌。

期刊:Molecular Cancer

影响因子:33.9

doi:10.1186/s12943-025-02464-x

Ma, Tianyun; Guo, Xiamei; Zhao, Jueying; Wang, Chenlong; Yu, Xiaojuan; Mo, Rongliang; Han, Zhuoying; Feng, Lulu; Liu, Longfei; Yu, Weiyong; Xu, Fangyi; Zhang, Li; Wang, Qilong; Luo, Chao

Chromatin-bound U2AF2 splicing factor ensures exon inclusion.

染色质结合的 U2AF2 剪接因子确保外显子包含。

期刊:Molecular Cell

影响因子:16.6

doi:10.1016/j.molcel.2025.04.013

Wu Weifang, Ahmad Kami, Henikoff Steven

U2AF2

发表日期：2025

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Genome-wide modulation of alternative splicing by a predicted alpha helix in U2AF2

U2AF2 中预测的 α 螺旋对全基因组选择性剪接的调控

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkaf1347.

Dingwu Xue,Liqiang Ai,Xiaoqin Wang,Yuxin Liu,Yuxuan Zhao,Jingxuan Ma,Ranhui Duan,Long Ma

THOC1 binds to U2AF2 and regulates ovarian cancer progression through the beta-catenin / c-myc / cyclinD1 signaling pathway.

THOC1 与 U2AF2 结合，并通过 β-catenin / c-myc / cyclinD1 信号通路调节卵巢癌的进展。

期刊:Cancer Cell International

影响因子:6

doi:10.1186/s12935-025-04034-z

Feng Yifan, Liu Jiaqi, Zhang Shuping, Zhang Zhe, Zhang Dong, Cao Yunxia, Li Min

U2AF2 Missense Variant Associated With Epilepsy and Systemic Dysmorphism: Report of Two Cases and Literature Review

U2AF2错义变异与癫痫和全身畸形相关：两例病例报告及文献综述

期刊:Clinical Case Reports

影响因子:0.6

doi:10.1002/ccr3.71182

Huang, Shiqin; Li, Mei; Yuan, Hai; Han, Yunli; Chen, Xiaolan; Su, Yunxuan; Li, Xing

The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export

FANCI/FANCD2复合物通过SRSF1介导的mRNA输出将DNA损伤反应与R环调控联系起来

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2023.113610

Anne Olazabal-Herrero, Boxue He, Youngho Kwon, Abhishek K Gupta, Arijit Dutta, Yuxin Huang, Prajwal Boddu, Zhuobin Liang, Fengshan Liang, Yaqun Teng, Li Lan, Xiaoyong Chen, Huadong Pei, Manoj M Pillai, Patrick Sung, Gary M Kupfer

RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation

RNA 和 RNA 结合蛋白 FUS 协同作用，阻止 TDP-43 空间分离

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2024.105716

Clément Demongin, Samuel Tranier, Vandana Joshi, Léa Ceschi, Bénédicte Desforges, David Pastré, Loic Hamon

U2AF2 controls alternative splicing in speckle-proximal regions in an RS domain-dependent manner

U2AF2 以 RS 结构域依赖的方式控制斑点近端区域的选择性剪接。

Vascular smooth muscle cell RNA-binding protein U2AF2 induces copper death by regulating C1qbp expression, delaying development of atherosclerosise.

血管平滑肌细胞 RNA 结合蛋白 U2AF2 通过调节 C1qbp 表达诱导铜死亡，延缓动脉粥样硬化的发展。

SF3B1 Phosphorylation Prompts U2AF2 Dissociation for Widespread Control of pre-mRNA Splicing

SF3B1磷酸化促进U2AF2解离，从而广泛调控前体mRNA剪接

HPGD induces ferroptosis and autophagy to suppress esophageal squamous cell carcinoma through the LXA4-ERK1/2-U2AF2-TFRC axis

HPGD通过LXA4-ERK1/2-U2AF2-TFRC轴诱导铁死亡和自噬，从而抑制食管鳞状细胞癌。

Chromatin-bound U2AF2 splicing factor ensures exon inclusion.

染色质结合的 U2AF2 剪接因子确保外显子包含。

Genome-wide modulation of alternative splicing by a predicted alpha helix in U2AF2

U2AF2 中预测的 α 螺旋对全基因组选择性剪接的调控

THOC1 binds to U2AF2 and regulates ovarian cancer progression through the beta-catenin / c-myc / cyclinD1 signaling pathway.

THOC1 与 U2AF2 结合，并通过 β-catenin / c-myc / cyclinD1 信号通路调节卵巢癌的进展。

U2AF2 Missense Variant Associated With Epilepsy and Systemic Dysmorphism: Report of Two Cases and Literature Review

U2AF2错义变异与癫痫和全身畸形相关：两例病例报告及文献综述

The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export

FANCI/FANCD2复合物通过SRSF1介导的mRNA输出将DNA损伤反应与R环调控联系起来

RNA and the RNA-binding protein FUS act in concert to prevent TDP-43 spatial segregation

RNA 和 RNA 结合蛋白 FUS 协同作用，阻止 TDP-43 空间分离