日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis of BAK sequestration by MCL-1 in apoptosis

MCL-1在细胞凋亡中对BAK的隔离的结构基础

Shagun Srivastava ,Giridhar Sekar ,Adedolapo Ojoawo ,Anup Aggarwal ,Elisabeth Ferreira ,Emiko Uchikawa ,Meek Yang ,Christy R Grace ,Raja Dey ,Yi-Lun Lin ,Cristina D Guibao ,Seetharaman Jayaraman ,Somnath Mukherjee ,Anthony A Kossiakoff ,Bin Dong ,Alexander Myasnikov ,Tudor Moldoveanu

Collaborative orchestration of BH3-only proteins governs Bak/Bax-dependent hepatocyte apoptosis under antiapoptotic protein-deficiency in mice

在小鼠抗凋亡蛋白缺乏的情况下,BH3结构域蛋白的协同调控控制着Bak/Bax依赖的肝细胞凋亡。

Shinnosuke Kudo # ,Hayato Hikita ,Yoshinobu Saito # ,Kazuhiro Murai ,Takahiro Kodama ,Tomohide Tatsumi ,Tetsuo Takehara

HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells

HRK下调和BCL-xL与BAK结合增强赋予治疗诱导的衰老黑色素瘤细胞凋亡保护作用

Clara Alcon ,Marta Kovatcheva ,Paula Morales-Sánchez ,Vanessa López-Polo ,Teresa Torres ,Susana Puig ,Albert Lu ,Josep Samitier ,Carlos Enrich ,Manuel Serrano ,Joan Montero

Inhibition of BAK-mediated apoptosis by the BH3-only protein BNIP5

BH3结构域蛋白BNIP5抑制BAK介导的细胞凋亡

Sebastian Rühl # ,Zhenrui Li # ,Shagun Srivastava ,Luigi Mari ,Clifford S Guy ,Mao Yang ,Tudor Moldoveanu ,Douglas R Green

Differential regulation of BAX and BAK apoptotic activity revealed by small molecules

小分子揭示BAX和BAK凋亡活性的差异调节

Kaiming Li, Yu Q Yap, Donia M Moujalled, Fransisca Sumardy, Yelena Khakham, Angela Georgiou, Michelle Jahja, Thomas E Lew, Melanie De Silva, Meng-Xiao Luo, Jia-Nan Gong, Zheng Yuan, Richard W Birkinshaw, Peter E Czabotar, Kym Lowes, David C S Huang, Benjamin T Kile, Andrew H Wei, Grant Dewson, Mark

Mitochondrial E3 ubiquitin ligase MARCHF5 controls BAK apoptotic activity independently of BH3-only proteins

线粒体E3泛素连接酶MARCHF5独立于BH3结构域蛋白调控BAK的凋亡活性。

Allan Shuai Huang ,Hui San Chin ,Boris Reljic ,Tirta M Djajawi ,Iris K L Tan ,Jia-Nan Gong ,David A Stroud ,David C S Huang ,Mark F van Delft # ,Grant Dewson #

Mitophagy restricts BAX/BAK-independent, Parkin-mediated apoptosis

线粒体自噬限制了不依赖于BAX/BAK的、由Parkin介导的细胞凋亡

Giovanni Quarato ,Luigi Mari ,Nicholas J Barrows ,Mao Yang ,Sebastian Ruehl ,Mark J Chen ,Cliff S Guy ,Jonathan Low ,Taosheng Chen ,Douglas R Green

Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization

来自人 BNIP5 和 PXT1 的肽以及促凋亡蛋白 BAK 的非天然结合物可以直接激活或抑制 BAK 介导的膜通透性。

Fiona Aguilar ,Stacey Yu ,Robert A Grant ,Sebastian Swanson ,Dia Ghose ,Bonnie G Su ,Kristopher A Sarosiek ,Amy E Keating

The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation

BAX 和 BAK 之间的相互作用调节凋亡孔的生长,从而控制线粒体 DNA 介导的炎症反应。

Katia Cosentino ,Vanessa Hertlein ,Andreas Jenner ,Timo Dellmann ,Milos Gojkovic ,Aida Peña-Blanco ,Shashank Dadsena ,Noel Wajngarten ,John S H Danial ,Jervis Vermal Thevathasan ,Markus Mund ,Jonas Ries ,Ana J Garcia-Saez

Ca2+-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak

Ca2+介导的线粒体内膜通透性增加可诱导细胞死亡,且该过程独立于Bax和Bak蛋白。

Giovanni Quarato ,Fabien Llambi ,Cliff S Guy ,Jaeki Min ,Marisa Actis ,Huan Sun ,Shilpa Narina ,Shondra M Pruett-Miller ,Junmin Peng ,Zoran Rankovic ,Douglas R Green