USP15相关文献与解析，生知库 | 链接生命科学的每一步

Influence of USP15 and its derived-peptide on non-small cell lung cancer immune evasion via regulating PD-L1 stability

USP15及其衍生肽通过调节PD-L1稳定性影响非小细胞肺癌的免疫逃逸

doi:10.1136/jitc-2025-014233

Wu, Di; Zeng, Ting; Lu, Ruo-Huang; Zhu, Wei; Wen, Qi; Mao, Xue-Li; Yu, Zheng-Zheng; Lin, Guo-Xiang; Peng, Yun-Xi; Lu, Shan-Shan; Yi, Hong; Huang, Wei; Xiao, Zhi-Qiang; Peng, Jinwu

Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation

靶向募集 USP15 可提高 CTLA4 的表面水平并抑制其降解。

期刊:Life Science Alliance

影响因子:3.3

doi:10.26508/lsa.202503563.

Francesca Querques,Victoria Ciampani,Pei Yee Tey,Victoria D Kutilek,Elma Kadic,Michael J Clague,Sylvie Urbé

USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment

USP15 通过 SMYD3/CCL2 依赖性髓系来源抑制细胞募集促进结直肠癌免疫逃逸

期刊:Cancer Immunology Research

影响因子:8.1

doi:10.1158/2326-6066.CIR-24-1194

Shuling Han #,Luying Cui #,Bojun Wang #,Yuli Ruan,Mengde Shi,Chang Hong,Xin Guan,Zhuo Chen,Yingjue Li,Yuanyu Liao,Ming Ma,Xiaolin Lu,Hong Wang,Yanqiao Zhang,Chao Liu

N6-methyladenosine-modification of USP15 regulates chemotherapy resistance by inhibiting LGALS3 ubiquitin-mediated degradation via AKT/mTOR signaling activation pathway in hepatocellular carcinoma

在肝细胞癌中，USP15的N6-甲基腺苷修饰通过AKT/mTOR信号通路激活抑制LGALS3泛素介导的降解，从而调节化疗耐药性。

期刊:Cell Death Discovery

影响因子:7

doi:10.1038/s41420-024-02282-y

Fang, Ronghuan; Jia, Zhigang; Xin, Yuhang; Zhao, Kai; Qin, Wei; Lu, Haoran; Zhou, Yi; Yang, Yongsheng; Fang, He

USP15-dependent modulation of TGF-Î²/Smad2/3 signaling: implications for chondrocyte matrix degradation and autophagy in osteoarthritis.

USP15 依赖性 TGF-β/Smad2/3 信号调节：对骨关节炎中软骨细胞基质降解和自噬的影响。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-21847-0

Yuan Zhikun, He Julun, Zhao Zihui, Chen Guanhao, Li Yanhui, Li Xuming

Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease

鉴定和验证 USP15 和 CUL2 作为慢性阻塞性肺疾病中泛素化相关生物标志物

期刊:Hereditas

影响因子:2.5

doi:10.1186/s41065-025-00460-1

Sun, Shulei; Zhang, Zhaoxiong; Zhao, Haiyan

Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis

发育转录因子TBX3的蛋白稳态再激活驱动BRAF/MAPK介导的肿瘤发生

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-48173-9

Zhenlei Zhang # ，Yufan Wu # ，Jinrong Fu # ，Xiujie Yu ，Yang Su ，Shikai Jia ，Huili Cheng ，Yan Shen ，Xianghui He ，Kai Ren ，Xiangqian Zheng ，Haixia Guan ，Feng Rao ，Li Zhao

Ectopic USP15 expression inhibits HIV-1 transcription involving changes in YY1 deubiquitination and stability

异位 USP15 表达抑制 HIV-1 转录，涉及 YY1 去泛素化和稳定性的变化

期刊:Frontiers in Cellular and Infection Microbiology

影响因子:4.6

doi:10.3389/fcimb.2024.1371655

Sahar Rezaei, Khalid A Timani, Ying Liu, Johnny J He

Retracted: Platelet-Rich Plasma-Derived Exosomal USP15 Promotes Cutaneous Wound Healing via Deubiquitinating EIF4A1

撤稿：富血小板血浆来源的外泌体USP15通过去泛素化EIF4A1促进皮肤伤口愈合

期刊:Oxidative Medicine and Cellular Longevity

影响因子:

doi:10.1155/2024/9808072

Longevity, Oxidative Medicine And Cellular

Deubiquitinase USP15 restricts LC3-dependent targeting of Mycobacterium tuberculosis.

去泛素化酶 USP15 限制 LC3 依赖性靶向结核分枝杆菌。

Influence of USP15 and its derived-peptide on non-small cell lung cancer immune evasion via regulating PD-L1 stability

USP15及其衍生肽通过调节PD-L1稳定性影响非小细胞肺癌的免疫逃逸

Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation

靶向募集 USP15 可提高 CTLA4 的表面水平并抑制其降解。

USP15 Facilitates Colorectal Cancer Immune Evasion through SMYD3/CCL2-Dependent Myeloid-Derived Suppressor Cell Recruitment

USP15 通过 SMYD3/CCL2 依赖性髓系来源抑制细胞募集促进结直肠癌免疫逃逸

N6-methyladenosine-modification of USP15 regulates chemotherapy resistance by inhibiting LGALS3 ubiquitin-mediated degradation via AKT/mTOR signaling activation pathway in hepatocellular carcinoma

在肝细胞癌中，USP15的N6-甲基腺苷修饰通过AKT/mTOR信号通路激活抑制LGALS3泛素介导的降解，从而调节化疗耐药性。

USP15-dependent modulation of TGF-Î²/Smad2/3 signaling: implications for chondrocyte matrix degradation and autophagy in osteoarthritis.

USP15 依赖性 TGF-β/Smad2/3 信号调节：对骨关节炎中软骨细胞基质降解和自噬的影响。

Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease

鉴定和验证 USP15 和 CUL2 作为慢性阻塞性肺疾病中泛素化相关生物标志物

Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis

发育转录因子TBX3的蛋白稳态再激活驱动BRAF/MAPK介导的肿瘤发生

Ectopic USP15 expression inhibits HIV-1 transcription involving changes in YY1 deubiquitination and stability

异位 USP15 表达抑制 HIV-1 转录，涉及 YY1 去泛素化和稳定性的变化

Retracted: Platelet-Rich Plasma-Derived Exosomal USP15 Promotes Cutaneous Wound Healing via Deubiquitinating EIF4A1

撤稿：富血小板血浆来源的外泌体USP15通过去泛素化EIF4A1促进皮肤伤口愈合