日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

WNK3 inhibition elicits antitumor immunity by suppressing PD-L1 expression on tumor cells and activating T-cell function

WNK3抑制通过抑制肿瘤细胞上的PD-L1表达和激活T细胞功能来诱导抗肿瘤免疫。

Hyun Ju Yoon # ,Gi-Cheon Kim # ,Sejin Oh ,Hakhyun Kim ,Yong Keon Kim ,Yunji Lee ,Min Seo Kim ,Gino Kwon ,Yeon-Su Ok ,Ho-Keun Kwon ,Hyun Seok Kim

Kinome-Wide Profiling Identifies Human WNK3 as a Target of Cajanin Stilbene Acid from Cajanus cajan (L.) Millsp

全激酶组分析鉴定出人WNK3是木豆(Cajanus cajan (L.) Millsp)来源的木豆芪酸的靶标。

Özenver, Nadire; Kadioglu, Onat; Fu, Yujie; Efferth, Thomas

Integrated miRNA, target mRNA, and metabolome profiling of Tinospora cordifolia with reference to berberine biosynthesis

参考小檗碱生物合成对心叶青牛胆的综合 miRNA、靶标 mRNA 和代谢组分析

Monica Saifi, Kudsiya Ashrafi, Nazima Nasrullah, Urvashi Bhardwaj, M Z Abdin

WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability via Regulation of KCC2 Cotransporter in Mature Neurons.

WNK3 通过调节成熟神经元中的 KCC2 共转运蛋白来维持 GABA 能抑制张力、突触兴奋和神经元兴奋性。

Melatonin modulates nitric oxide-regulated WNK-SPAK/OSR1-NKCC1 signaling in dorsal raphe nucleus of rats

褪黑素调节大鼠背缝核中一氧化氮调控的WNK-SPAK/OSR1-NKCC1信号通路

Hye Jin Yang ,Mi Jung Kim ,Sung Soo Kim ,Young-Wuk Cho

WNK3 and WNK4 exhibit opposite sensitivity with respect to cell volume and intracellular chloride concentration

WNK3 和 WNK4 对细胞体积和细胞内氯离子浓度的敏感性相反。

Pacheco-Alvarez, Diana; Carrillo-Pérez, Diego Luis; Mercado, Adriana; Leyva-Ríos, Karla; Moreno, Erika; Hernández-Mercado, Elisa; Castañeda-Bueno, María; Vázquez, Norma; Gamba, Gerardo

Brn3a and Brn3b knockout mice display unvaried retinal fine structure despite major morphological and numerical alterations of ganglion cells

Brn3a 和 Brn3b 基因敲除小鼠的视网膜精细结构没有变化,尽管神经节细胞的形态和数量发生了重大变化

Miruna Georgiana Ghinia, Elena Novelli, Szilard Sajgo, Tudor Constantin Badea, Enrica Strettoi

Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke

小鼠体内WNK3-SPAK激酶复合物的缺失可改善缺血性卒中后恶性脑水肿的影像学和临床预后。

Zhao, Hanshu; Nepomuceno, Rachel; Gao, Xin; Foley, Lesley M; Wang, Shaoxia; Begum, Gulnaz; Zhu, Wen; Pigott, Victoria M; Falgoust, Lindsay M; Kahle, Kristopher T; Yang, Sung-Sen; Lin, Shih-Hua; Alper, Seth L; Hitchens, T Kevin; Hu, Shaoshan; Zhang, Zhongling; Sun, Dandan

LINGO-1 receptor promotes neuronal apoptosis by inhibiting WNK3 kinase activity.

LINGO-1 受体通过抑制 WNK3 激酶活性促进神经元凋亡。

A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo

WNK3在体内调节肾脏NKCC2和NCC共转运蛋白磷酸化中的作用较小

Oi, Katsuyuki; Sohara, Eisei; Rai, Tatemitsu; Misawa, Moko; Chiga, Motoko; Alessi, Dario R; Sasaki, Sei; Uchida, Shinichi