日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

MCM10, a novel YAP1/TEAD4 target, drives gastric cancer progression by bridging DNA replication to stemness acquisition

MCM10 是一种新型的 YAP1/TEAD4 靶点，它通过连接 DNA 复制和干细胞特性获得来驱动胃癌的进展。

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-026-02623-8
Xie, Fuda; Leung, Hoi Wing; Lyu, Yang; Yu, Peiyao; Feng, Tiejun; Chen, Bonan; Wu, Jialin; Tham, Jenson; Fang, Canbin; Cheung, Alvin H K; Chow, Chit; Jiang, Jianhui; Hu, Jintao; Zhang, Fengbin; Zhu, Chaowei; Zhong, Keli; Sun, Meiheng; Zhang, Ge; Yu, Sifan; Xu, Dazhi; Wang, Shouyu; Huang, Bing; Zhuang, Kangmin; Luo, Xiaobei; Li, Aimin; Guo, Qing; Gao, Chanchan; Zhang, Bin; Ma, Yuan; Wu, William Kk; An, Liwei; Wong, Chi Chun; Yu, Jun; To, Ka Fai; Kang, Wei
胃癌
肿瘤
YAP1
MCM10
肿瘤免疫
细胞生物学
YAP
干细胞
发育与干细胞
发表日期：2026
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YAP1 defines an emergent, plastic population of relapsed small cell lung cancer

YAP1定义了复发性小细胞肺癌中一种新兴的、可塑性的细胞群。

期刊:Journal of Thoracic Oncology
影响因子:20.8
doi:10.1016/j.jtho.2026.103730
Stewart, C Allison; Ramkumar, Kavya; Wang, Runsheng; Xi, Yuanxin; Halliday, Alexa; Diao, Lixia; Wang, Qi; Serrano, Alejandra; Groves, Sarah; Heeke, Simon; Tanimoto, Azusa; Kaiser, Laura; Lewis, Whitney; Bose, Mukulika; Da Rocha, Pedro; Karacosta, Loukia; Quaranta, Vito; Wang, Jing; George, Julie; Solis Soto, Luisa Maren; Zhang, Bingnan; Heymach, John V; Byers, Lauren A; Gay, Carl M
YAP
细胞生物学
YAP1
肺癌
肿瘤
肿瘤免疫
发表日期：2026
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Engineered intestinal crypt geometry uncovers YAP1-dependent fetal-to-adult transition

工程化肠隐窝几何结构揭示了YAP1依赖的胎儿到成人的转变

期刊:Cell Stem Cell
影响因子:20.4
doi:10.1016/j.stem.2026.01.006
Maimets, Martti; Nikolaev, Mikhail; Lövkvist, Cecilia; Bertillot, Fabien; Larsen, Hjalte List; Bressan, Raul Bardini; Georgantzoglou, Antonios; Gjorevski, Nikolce; Filidou, Eirini; Zøylner, Maureen; Hansen, Stine Lind; Baattrup, Astrid M; Banjac, Isidora; Guiu, Jordi; Wickström, Sara A; Lutolf, Matthias P; Jensen, Kim B
YAP
YAP1
发表日期：2026
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Correction: FOXP4 Is a Direct YAP1 Target That Promotes Gastric Cancer Stemness and Drives Metastasis

更正：FOXP4 是 YAP1 的直接靶点，可促进胃癌干细胞特性并驱动转移。

期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-25-5025
Liu, Xiaoli; Chen, Bonan; Xie, Fuda; Wong, Kit Yee; Cheung, Alvin H K; Zhang, Jinglin; Wu, Qian; Fang, Canbin; Hu, Jintao; Wang, Shouyu; Xu, Dazhi; Chen, Jianwu; Wang, Yuzhi; Wong, Chi Chun; Chen, Huarong; Wu, William K K; Yu, Jun; Chan, Michael W Y; Tsang, Chi Man; Lo, Kwok Wai; Tse, Gary M K; To, Ka-Fai; Kang, Wei
胃癌
肿瘤
YAP1
肿瘤免疫
细胞生物学
YAP
干细胞
发育与干细胞
发表日期：2026
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Activation of the YAP1/pSTAT3/NRP1 axis in peritendinous sensory nerves promotes tendon healing

肌腱周围感觉神经中YAP1/pSTAT3/NRP1轴的激活促进肌腱愈合

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.aec1272.
Jiayi Wang,Fan Wang,Jingwen Liu,Yao Xiao,Zhaoyang Li,Xiaonan Liu,Peilin Zhang,Fei Wang,Wenguo Cui,Shen Liu
神经科学
NRP1
STAT3
YAP1
YAP
发表日期：2026
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Targeting YAP1-CD70 axis potentiates the efficacy of anti-PD-1 therapy in prostate cancer

靶向YAP1-CD70轴可增强抗PD-1疗法在前列腺癌中的疗效

期刊:Biomarker Research
影响因子:11.5
doi:10.1186/s40364-025-00880-1
Tong, Tongyu; Guan, Yupeng; Luo, Juan; Yan, Binyuan; Yang, Xiangwei; Zhang, Junfu; Yang, Zheng; Cao, Fei; Sun, Guangxi; Zeng, Hao; Li, Peng; Pang, Jun
YAP1
CD7
前列腺癌
肿瘤
PD-1
肿瘤免疫
YAP
CD70
发表日期：2026
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CDH4/UBA1/RBMX axis promotes polycystic ovary syndrome progression through YAP1 activation

CDH4/UBA1/RBMX轴通过YAP1激活促进多囊卵巢综合征的进展。

期刊:Cellular & Molecular Biology Letters
影响因子:10.2
doi:10.1186/s11658-026-00900-4
Xu, Ning; Yu, Bo; Li, Yingying; Yang, Yuxi; Wang, Yalong; Fang, Lingling; Wu, Hongliang; Luan, Yingyi; Yin, Chenghong
YAP1
多囊卵巢综合征
BMX
YAP
UBA1
免疫/内分泌
发表日期：2026
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CCL24 recruits CCR3(+) TAMs to promote immunosuppression via YAP1 activation and serves as a therapeutic target for Gracillin in colorectal cancer

CCL24通过激活YAP1募集CCR3(+)肿瘤相关巨噬细胞(TAM)促进免疫抑制，并可作为结直肠癌中格拉西林治疗的靶点。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.127341
Huang, Shiyu; Lin, Wanqiong; Ding, Xu; Shi, Jinjun; Liu, Fei; Wang, Guoqing; Gao, Chanchan; Su, Xiangyu
巨噬细胞
肿瘤
肠癌
CCR3
YAP1
肿瘤免疫
CCL2
巨噬细胞
YAP
CCL24
细胞生物学
免疫/内分泌
发表日期：2026
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Interaction between m6A and YAP1 mechanotransduction pathways is essential for mechanical memory and matrix remodeling in pancreatic cancer

m6A和YAP1机械转导通路之间的相互作用对于胰腺癌的机械记忆和基质重塑至关重要。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.125330
Chen, Jiaoshun; Wang, Gengqiao; Zhang, Haoxiang; Hu, Qingyi; Zhao, Jun; Shen, Qiang; Duan, Qingke; Yin, Tao
m6A/m5C/m7G
肿瘤
YAP1
肿瘤免疫
信号转导
YAP
胰腺癌
发表日期：2026
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NEDD4 promotes reactive astrogliosis by enhancing K63-linked ubiquitination and inhibiting chaperone-mediated autophagy degradation of YAP1.

NEDD4 通过增强 K63 连接的泛素化和抑制分子伴侣介导的 YAP1 自噬降解来促进反应性星形胶质增生。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.123639
Ye Wu, Li Yigang, Wang Wei, Pan Dishui, Wang Xiaokun, Gu Yao, Zhu Yufeng, Wang Haofan, Lu Xuanyu, Jiang Dongdong, Tang Pengyu, Shu Haoming, Ma Jun, Cai Weihua
表观遗传
YAP
YAP1
NEDD4
Autophagy
自噬
泛素化
发表日期：2026
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