ZEB2相关文献与解析，生知库 | 链接生命科学的每一步

Yang, Zhengkun; Wang, Huiyi; Xiao, Junhong; Yang, Qiudong; Sun, Jiahui; Liu, Heyu; Huang, Zhendong; Ma, Li; Huang, Xin; Wang, Chuan; Wang, Xiaoxuan; Cao, Zhengguo

乳酸化

细胞生物学

ZEB2

发表日期：2026

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Hyperglycemia-induced P300/CBP acetyltransferase drives ZEB2-mediated proinflammatory macrophages and delays wound healing

高血糖诱导的P300/CBP乙酰转移酶驱动ZEB2介导的促炎巨噬细胞增殖，延缓伤口愈合。

期刊:JCI Insight

影响因子:6.1

doi:10.1172/jci.insight.192146

Roy, Soumyajit; Patra, Debarun; Ramprasad, Palla; Sharma, Shivam; Katiyar, Parul; Bawa, Ashvind; Singh, Kanhaiya; Tikoo, Kulbhushan; Dasgupta, Suman; Sen, Chandan K; Pal, Durba

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

【已撤稿】下调的microRNA-200a通过靶向E-钙黏蛋白抑制因子ZEB1/ZEB2，经由Wnt/β-catenin通路促进胃腺癌中的EMT和肿瘤生长

期刊:Oncology Reports

影响因子:3.9

doi:10.3892/or.2026.9045

Cong, Ningning; Du, Ping; Zhang, Anling; Shen, Fajuan; Su, Juan; Pu, Peiyu; Wang, Tao; Zjang, Jie; Kang, Chunsheng; Zhang, Qingyu

Transcription factor ZEB2 is essential for ureteral smooth muscle cell differentiation.

转录因子 ZEB2 对输尿管平滑肌细胞分化至关重要。

期刊:PLoS Genetics

影响因子:3.7

doi:10.1371/journal.pgen.1012028

Kumar Sudhir, Fan Xueping, Pattam Harshita, Yan Kun, Liaw Easton J, Ji Jiayi, Zaltz Emily, Song Paul, Jiang Yuqiao, Nishizaki Yuriko, Higashi Yujiro, Cai Chen-Leng, Lu Weining

Case Report: Identification of a de novo missense variant in the N-terminal zinc-finger domain of ZEB2 in a patient presenting with neurodevelopmental delay and recurrent pulmonary infections

病例报告：在一名表现为神经发育迟缓和反复肺部感染的患者中，鉴定出ZEB2 N端锌指结构域的新生错义变异

期刊:Frontiers in Genetics

影响因子:2.8

doi:10.3389/fgene.2026.1778727

Chen, Jing; Jiang, Xiaodong; Su, Wei; Li, Jingjing; Chen, Shuang; Xu, Ke; Teng, Juxian; Zhang, Weihong; Zhu, Hongmin

Downregulation of Long Noncoding RNA TUG1 Inhibits Proliferation and Induces Apoptosis Through the TUG1/miR-142/ZEB2 Axis in Bladder Cancer Cells [Retraction]

长链非编码RNA TUG1下调通过TUG1/miR-142/ZEB2轴抑制膀胱癌细胞增殖并诱导细胞凋亡[撤稿]

期刊:Oncotargets and Therapy

影响因子:2.8

doi:10.2147/OTT.S614701

Epidermal Stem Cell-Derived Extracellular Vesicles Induce Fibroblasts Mesenchymal-Epidermal Transition to Alleviate Hypertrophic Scar Formation via miR-200s Inhibition of ZEB1 and 2

表皮干细胞来源的细胞外囊泡通过miR-200抑制ZEB1和ZEB2诱导成纤维细胞间质-表皮转化，从而减轻肥厚性瘢痕形成。

期刊:Journal of Extracellular Vesicles

影响因子:15.5

doi:10.1002/jev2.70160

Miao Zhen ，Juntao Xie ，Rui Yang ，Lijuan Liu ，Hengdeng Liu ，Xuefeng He ，Suyue Gao ，Junyou Zhu ，Jingting Li ，Bin Shu ，Peng Wang

Hypoxia-Induced circPRELID2 Promotes Gastric Cancer Metastasis by Facilitating ZEB2 Translation via PCBP1 O-GlcNAcylation.

缺氧诱导的 circPRELID2 通过 PCBP1 O-GlcNAc 化促进 ZEB2 翻译，从而促进胃癌转移。

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202505396

Erratum: Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression: Erratum

勘误：长链非编码RNA UICLM通过作为microRNA-215的ceRNA调控ZEB2表达，促进结直肠癌肝转移：勘误

期刊:Theranostics

影响因子:13.3

doi:10.7150/thno.108968

Chen, Dong-Liang; Lu, Yun-Xin; Zhang, Jia-Xing; Wei, Xiao-Li; Wang, Feng; Zeng, Zhao-Lei; Pan, Zhi-Zhong; Yuan, Yun-Fei; Wang, Feng-Hua; Pelicano, Helene; Chiao, Paul J; Huang, Peng; Xie, Dan; Li, Yu-Hong; Ju, Huai-Qiang; Xu, Rui-Hua

The transcription factor ZEB2 mediates the antitumor efficacy of tumor-infiltrating lymphocytes in non-small cell lung cancer

转录因子ZEB2介导肿瘤浸润淋巴细胞在非小细胞肺癌中的抗肿瘤功效

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-025-08112-y

Wang, Jiajia; Liu, Fei; Li, Yongyong; Gao, Jiaojiao; Yang, Shasha; Tian, Mei; Deng, Lili; Yang, Yan; Gong, Beilei; Zhao, Chengling; Gong, Huiyuan; Xie, Zongyu; Zhou, Yongchun; Huang, Rongzhong; Luo, Qiang; Jiang, Depeng; Wang, Xiaojing

KDM6B/Pdk1 glycolytic pathway-driven ZEB2 lactylation promotes cellular cementum formation

KDM6B/Pdk1糖酵解途径驱动的ZEB2乳酸化促进细胞牙骨质形成

Hyperglycemia-induced P300/CBP acetyltransferase drives ZEB2-mediated proinflammatory macrophages and delays wound healing

高血糖诱导的P300/CBP乙酰转移酶驱动ZEB2介导的促炎巨噬细胞增殖，延缓伤口愈合。

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

【已撤稿】下调的microRNA-200a通过靶向E-钙黏蛋白抑制因子ZEB1/ZEB2，经由Wnt/β-catenin通路促进胃腺癌中的EMT和肿瘤生长

Transcription factor ZEB2 is essential for ureteral smooth muscle cell differentiation.

转录因子 ZEB2 对输尿管平滑肌细胞分化至关重要。

Case Report: Identification of a de novo missense variant in the N-terminal zinc-finger domain of ZEB2 in a patient presenting with neurodevelopmental delay and recurrent pulmonary infections

病例报告：在一名表现为神经发育迟缓和反复肺部感染的患者中，鉴定出ZEB2 N端锌指结构域的新生错义变异

Downregulation of Long Noncoding RNA TUG1 Inhibits Proliferation and Induces Apoptosis Through the TUG1/miR-142/ZEB2 Axis in Bladder Cancer Cells [Retraction]

长链非编码RNA TUG1下调通过TUG1/miR-142/ZEB2轴抑制膀胱癌细胞增殖并诱导细胞凋亡[撤稿]

Epidermal Stem Cell-Derived Extracellular Vesicles Induce Fibroblasts Mesenchymal-Epidermal Transition to Alleviate Hypertrophic Scar Formation via miR-200s Inhibition of ZEB1 and 2

表皮干细胞来源的细胞外囊泡通过miR-200抑制ZEB1和ZEB2诱导成纤维细胞间质-表皮转化，从而减轻肥厚性瘢痕形成。

Hypoxia-Induced circPRELID2 Promotes Gastric Cancer Metastasis by Facilitating ZEB2 Translation via PCBP1 O-GlcNAcylation.

缺氧诱导的 circPRELID2 通过 PCBP1 O-GlcNAc 化促进 ZEB2 翻译，从而促进胃癌转移。

Erratum: Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression: Erratum

勘误：长链非编码RNA UICLM通过作为microRNA-215的ceRNA调控ZEB2表达，促进结直肠癌肝转移：勘误

The transcription factor ZEB2 mediates the antitumor efficacy of tumor-infiltrating lymphocytes in non-small cell lung cancer

转录因子ZEB2介导肿瘤浸润淋巴细胞在非小细胞肺癌中的抗肿瘤功效