日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacologically increasing cGMP improves proteostasis and reduces neuropathy in mouse models of CMT1

药理学上增加 cGMP 可改善 CMT1 小鼠模型中的蛋白质稳态并减少神经病变

Seth M Moore, Joseph Gawron, Mckayla Stevens, Leandro N Marziali, Emmanuel S Buys, G Todd Milne, Maria Laura Feltri, Jordan J S VerPlank

Ablation of lipocalin-2 reduces neuroinflammation in a mouse model of Krabbe disease

脂质运载蛋白-2 的消融可减少克拉伯病小鼠模型中的神经炎症

Jacob Favret, Malabika Maulik, Rayan Masoom, Meghana Kushwaha, Devin Thompson, Richard Browne, Daesung Shin

64Cu-labeled daratumumab F(ab')2 fragment enables early visualization of CD38-positive lymphoma

64Cu 标记的达雷木单抗 F(ab')2 片段可实现 CD38 阳性淋巴瘤的早期可视化

Lei Kang, Cuicui Li, Qi Yang, Logan Sutherlin, Lin Wang, Zhao Chen, Kaelyn V Becker, Nan Huo, Yongkang Qiu, Jonathan W Engle, Rongfu Wang, Chengzhi He, Dawei Jiang, Xiaojie Xu, Weibo Cai1

Protein kinase C-mediated phosphorylation of transient receptor potential melastatin type 2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold

蛋白激酶 C 介导的瞬时受体电位黑素 2 型 Thr738 磷酸化抵消细胞浆 Ca2+ 的作用并提高温度阈值

Makiko Kashio, Satoru Masubuchi, Makoto Tominaga

Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons

癫痫和去极化的海马神经元中 GABAA 受体的神经甾体增强作用降低

Suchitra Joshi, William H Roden, Jaideep Kapur, Laura A Jansen

Peptidomimetic Polo-Box-Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor

肽模拟 Polo-Box 靶向抑制剂,可作用于肿瘤细胞中的 PLK1,并选择性作用于 PLK3 肿瘤抑制因子

Merissa Baxter, Danda Chapagai, Sandra Craig, Cecilia Hurtado, Jessy Varghese, Elmar Nurmemmedov, Michael D Wyatt, Campbell McInnes

Application of high-throughput, capillary-based Western analysis to modulated cleavage of the cellular prion protein

应用高通量、基于毛细管的 Western 分析来调节细胞朊病毒蛋白的裂解

Andrew R Castle, Nathalie Daude, Sabine Gilch, David Westaway

AAV Mediated Delivery of Myxoma Virus M013 Gene Protects the Retina against Autoimmune Uveitis

AAV 介导的粘液瘤病毒 M013 基因传递可保护视网膜免受自身免疫性葡萄膜炎的侵害

Raela B Ridley, Brianna M Young, Jieun Lee, Erin Walsh, Chulbul M Ahmed, Alfred S Lewin, Cristhian J Ildefonso

How Supraphysiological Oxygen Levels in Standard Cell Culture Affect Oxygen-Consuming Reactions

标准细胞培养中的超生理氧水平如何影响耗氧反应

Jeffrey A Stuart, Joao Fonseca, Fereshteh Moradi, Cassandra Cunningham, Bishoy Seliman, Cydney R Worsfold, Sarah Dolan, John Abando, Lucas A Maddalena

Impact of image segmentation on high-content screening data quality for SK-BR-3 cells

图像分割对 SK-BR-3 细胞高内涵筛选数据质量的影响

Andrew A Hill, Peter LaPan, Yizheng Li, Steve Haney