日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Regulation of ubiquitination and antiviral activity of Cactin by deubiquitinase Usp14 in Drosophila

果蝇去泛素化酶Usp14对仙人掌素泛素化及抗病毒活性的调控

Qiqi Rong, Zhichong Xi, Dongyang Guo, Wen Xu, Liqin Zhang, Qingfa Wu

Saracatinib prompts hemin-induced K562 erythroid differentiation but suppresses erythropoiesis of hematopoietic stem cells

Saracatinib 可促进血红素诱导的 K562 红系分化,但抑制造血干细胞的红细胞生成。

Lina Ding #,Diyu Chen #,Yuanshuai Li,Yingjun Xie,Xiaofang Sun,Ding Wang

JS06.5.A TUCATINIB, TRASTUZUMAB, AND CAPECITABINE WITH STEREOTACTIC RADIOSURGERY IN PATIENTS WITH BRAIN METASTASES FROM HER-2 POSITIVE BREAST CANCER (TUTOR): A MULTICENTER PHASE 1 CLINICAL TRIAL

JS06.5.A TUCATINIB、TRASTUZUMAB 和 CAPECITABINE 联合立体定向放射外科治疗 HER-2 阳性乳腺癌脑转移患者 (TUTOR):一项多中心 1 期临床试验

Grover, Sandeep; Avasthi, Ajit; Chakravarty, Rahul; Dan, Amitava; Chakraborty, Kaustav; Neogi, Rajarshi; Desousa, Avinash; Nayak, Omkar P; Praharaj, Samir Kumar; Menon, Vikas; Deep, Raman; Bathla, Manish; Subramanyam, Alka A; Nebhinani, Naresh; Ghosh, Prasonjit; Lakdawala, Bhaveshkumar; Bhattacharya, Ranjan; Ahluwalia, M S; Khosla, A A; Ozair, A; Kotecha, R R; McDermott, M W; Mehta, M P; Sandoval-Leon, A C; Mahtani, R; Peereboom, D M

SDE2 is an essential gene required for ribosome biogenesis and the regulation of alternative splicing

SDE2 是核糖体生物合成和调节可变剪接所必需的基因

Jess Floro, Anqi Dai, Abigail Metzger, Alexandra Mora-Martin, Neil J Ganem, Daniel Cifuentes, Ching-Shyi Wu, Jasbir Dalal, Shawn M Lyons, Adam Labadorf, Rachel L Flynn

Structural investigations, quantum mechanical studies on proton and metal affinity and biological activity predictions of selpercatinib.

对 selpercatinib 进行结构研究、质子和金属亲和力的量子力学研究以及生物活性预测。

53. TUCATINIB VS PLACEBO ADDED TO TRASTUZUMAB AND CAPECITABINE FOR PATIENTS WITH PREVIOUSLY TREATED HER2+ METASTATIC BREAST CANCER (MBC) WITH BRAIN METASTASES (BM) (HER2CLIMB)

53. TUCATINIB 与安慰剂联合曲妥珠单抗和卡培他滨治疗既往接受过治疗的 HER2+ 转移性乳腺癌 (MBC) 伴脑转移 (BM) 患者的疗效比较 (HER2CLIMB)

Bashour, Sami I; Ibrahim, Nuhad K; Schomer, Donald F; Hess, Kenneth R; Gao, Chao; Tripathy, Debu; Fuller, Gregory N; Weinberg, Jeffrey; McAleer, Mary Frances; Tawbi, Hussein; Lang, Frederick; Palmer, Joshua; Klamer, Brett; Ballman, Karla; Brown, Paul; Cerhan, Jane; Anderson, Keith; Whitton, Anthony; Greenspoon, Jeffrey; Chung, Caroline; Burri, Stuart; Parney, Ian; Stieber, Volker; Pollock, Bruce; Laack, Nadia; Ashman, Jonathon; Bahary, Jean-Paul; Barker, Fred; Galanis, Evanthia; Asher, Anthony; Roberge, David; Lin, Nancy; Murthy, Rashmi; Anders, Carey; Borges, Virginia; Hurvitz, Sara; Loi, Sherene; Abramson, Vandana; Bedard, Philippe; Oliveira, Mafalda; Zelnack, Amelia; DiGiovanna, Michael; Bachelot, Thomas; Chien, A Jo; O’Regan, Ruth; Wardley, Andrew; Mueller, Volkmar; Carey, Lisa; McGoldrick, Suzanne; An, Xuebei; Winer, Eric

Modelling the structural and reactivity landscapes of tucatinib with special reference to its wavefunction-dependent properties and screening for potential antiviral activity.

对 tucatinib 的结构和反应性进行建模,特别关注其波函数依赖性特性,并筛选其潜在的抗病毒活性。

Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors

Saracatinib 可抑制对 Met 和成纤维细胞生长因子受体抑制剂耐药的弥漫型胃癌细胞的腹膜播散。

Hideki Yamaguchi,Miho Takanashi, Nachi Yoshida, Yuumi Ito, Reiko Kamata, Kiyoko Fukami, Kazuyoshi Yanagihara, Ryuichi Sakai