HLA-DR相关文献与解析，生知库 | 链接生命科学的每一步

Huidong Guo ，Bixia Wang ，Zhigui Wu ，Qi Zhang ，Xinya Jiang ，Fangqing Zhang ，Jingrui Zhou ，Shuang Fan ，Yang Zhou ，Zheng-Li Xu ，Yu Wang ，Xiang-Yu Zhao ，Xiao-Jun Huang

CD8

细胞生物学

CD27

The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients

CD38+HLA-DR+ T细胞的活化和耗竭特征可作为COVID-19患者病情严重程度和死亡率的预测指标

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2025.1577803

Qiuyue Long # ，Shixu Song # ，Jianbo Xue # ，Wenyi Yu ，Yaolin Zheng ，Jiwei Li ，Jing Wu ，Xiaoyi Hu ，Mingzheng Jiang ，Hongli Ye ，Binghan Zheng ，Minghui Wang ，Fangfang Wu ，Ke Li ，Zhancheng Gao ，Yali Zheng

Overexpression of hsa-HLA-DRB1 may delay diabetic wound healing and angiogenesis by regulating miRNA_12118 and FLT-1

hsa-HLA-DRB1 的过度表达可能通过调节 miRNA_12118 和 FLT-1 来延缓糖尿病伤口愈合和血管生成。

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-025-03906-8

Chao Bai # ,Wenwen Yang # ,Jianghao Yan ,Guangwei Qi ,Liuyu Yang ,Qingrui Wu ,Jieguang Peng ,Jun Luo ,Tao Liu

Frequency of HLA-DR+CD38hi T cells identifies and quantifies T-cell activation in hemophagocytic lymphohistiocytosis, hyperinflammation, and immune regulatory disorders

HLA-DR+CD38hi T 细胞的频率可用于识别和量化噬血细胞性淋巴组织细胞增生症、过度炎症和免疫调节紊乱中的 T 细胞活化。

期刊:Journal of Allergy and Clinical Immunology

影响因子:11.4

doi:10.1016/j.jaci.2023.07.008

Thinh H Nguyen ，Deepak Kumar ，Chengyu Prince ，Dylan Martini ，Jocelyn R Grunwell ，Taylor Lawrence ，Trenton Whitely ，Karin Chappelle ，Satheesh Chonat ，Sampath Prahalad ，Michael Briones ，Shanmuganathan Chandrakasan

Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?

血小板裂解物时代间充质干细胞HLA-DR的表达：MSCs的过时释放标准？

期刊:Journal of Translational Medicine

影响因子:6.1

doi:10.1186/s12967-023-04684-5

Zyrafete Kuçi ，Natascha Piede ，Kathrin Vogelsang ，Lisa-Marie Pfeffermann ，Sibylle Wehner ，Emilia Salzmann-Manrique ，Miriam Stais ，Hermann Kreyenberg ，Halvard Bonig ，Peter Bader ，Selim Kuçi

Genome-based prediction of cross-protective, HLA-DR-presented epitopes as putative vaccine antigens for multiple Bordetella species

基于基因组的交叉保护性HLA-DR呈递表位预测，作为多种博德特氏菌的潜在疫苗抗原

期刊:Microbiology Spectrum

影响因子:3.7

doi:10.1128/spectrum.03527-23

Muktha S Natrajan ，Jesse M Hall ，Michael R Weigand ，Yanhui Peng ，Margaret M Williams ，Mohamed Momin ，Frederick Heath Damron ，Purnima Dubey ，Maria Lucia Tondella ，Lucia C Pawloski

发表日期：2024

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HLA-DR-Expressing Fibroblast-Like Synoviocytes Are Inducible Antigen Presenting Cells That Present Autoantigens in Lyme Arthritis

表达HLA-DR的成纤维细胞样滑膜细胞是可诱导的抗原呈递细胞，可在莱姆关节炎中呈递自身抗原。

期刊:ACR Open Rheumatology

影响因子:2.9

doi:10.1002/acr2.11710

Joseph R Rouse ，Rebecca Danner ，Amanda Wahhab ，Michaela Pereckas ，Christine Nguyen ，Mecaila E McClune ，Allen C Steere ，Klemen Strle ，Brandon L Jutras ，Robert B Lochhead

Increased CD14+HLA-DR-/low myeloid-derived suppressor cells can be regarded as a biomarker on disease severity and response to therapy in acute coronary syndrome

CD14+HLA-DR-/low髓源性抑制细胞增多可被视为急性冠脉综合征中疾病严重程度和治疗反应的生物标志物。

期刊:PeerJ

影响因子:2.3

doi:10.7717/peerj.18154

Yinsheng Tan # ，Mingde Ren # ，Jie Hou ，Tao Hou ，Xianhe Lin

Single-cell transcriptome profiling of sepsis identifies HLA-DRlowS100Ahigh monocytes with immunosuppressive function

脓毒症单细胞转录组分析鉴定出具有免疫抑制功能的HLA-DRlowS100Ahigh单核细胞

期刊:Military Medical Research

影响因子:16.7

doi:10.1186/s40779-023-00462-y

Ren-Qi Yao # ，Peng-Yue Zhao # ，Zhi-Xuan Li # ，Yu-Yang Liu # ，Li-Yu Zheng ，Yu Duan ，Lu Wang ，Rong-Li Yang ，Hong-Jun Kang ，Ji-Wei Hao ，Jing-Yan Li ，Ning Dong ，Yao Wu ，Xiao-Hui Du ，Feng Zhu ，Chao Ren ，Guo-Sheng Wu ，Zhao-Fan Xia ，Yong-Ming Yao

Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson's disease

α-突触核蛋白表位与HLA-DRB1∗15:01的相互作用会在小鼠中引发类似于帕金森病前驱期的肠道症状

期刊:Neuron

影响因子:14.7

doi:10.1016/j.neuron.2023.07.015

Francesca Garretti ，Connor Monahan ，Nicholas Sloan ，Jamie Bergen ，Sanjid Shahriar ，Seon Woo Kim ，Alessandro Sette ，Tyler Cutforth ，Ellen Kanter ，Dritan Agalliu ，David Sulzer

CD8+HLA-DR+CD27+ T cells define a population of naturally occurring regulatory precursors in humans

CD8+HLA-DR+CD27+ T 细胞定义了人类体内天然存在的一类调节性前体细胞。

The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients

CD38+HLA-DR+ T细胞的活化和耗竭特征可作为COVID-19患者病情严重程度和死亡率的预测指标

Overexpression of hsa-HLA-DRB1 may delay diabetic wound healing and angiogenesis by regulating miRNA_12118 and FLT-1

hsa-HLA-DRB1 的过度表达可能通过调节 miRNA_12118 和 FLT-1 来延缓糖尿病伤口愈合和血管生成。

Frequency of HLA-DR+CD38hi T cells identifies and quantifies T-cell activation in hemophagocytic lymphohistiocytosis, hyperinflammation, and immune regulatory disorders

HLA-DR+CD38hi T 细胞的频率可用于识别和量化噬血细胞性淋巴组织细胞增生症、过度炎症和免疫调节紊乱中的 T 细胞活化。

Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?

血小板裂解物时代间充质干细胞HLA-DR的表达：MSCs的过时释放标准？

Genome-based prediction of cross-protective, HLA-DR-presented epitopes as putative vaccine antigens for multiple Bordetella species

基于基因组的交叉保护性HLA-DR呈递表位预测，作为多种博德特氏菌的潜在疫苗抗原

HLA-DR-Expressing Fibroblast-Like Synoviocytes Are Inducible Antigen Presenting Cells That Present Autoantigens in Lyme Arthritis

表达HLA-DR的成纤维细胞样滑膜细胞是可诱导的抗原呈递细胞，可在莱姆关节炎中呈递自身抗原。

Increased CD14+HLA-DR-/low myeloid-derived suppressor cells can be regarded as a biomarker on disease severity and response to therapy in acute coronary syndrome

CD14+HLA-DR-/low髓源性抑制细胞增多可被视为急性冠脉综合征中疾病严重程度和治疗反应的生物标志物。

Single-cell transcriptome profiling of sepsis identifies HLA-DRlowS100Ahigh monocytes with immunosuppressive function

脓毒症单细胞转录组分析鉴定出具有免疫抑制功能的HLA-DRlowS100Ahigh单核细胞

Interaction of an α-synuclein epitope with HLA-DRB1∗15:01 triggers enteric features in mice reminiscent of prodromal Parkinson's disease

α-突触核蛋白表位与HLA-DRB1∗15:01的相互作用会在小鼠中引发类似于帕金森病前驱期的肠道症状