Phosphorylation of STAT3 at Tyr705 contributes to TFEB-mediated autophagy-lysosomal pathway dysfunction and leads to ischemic injury in rats
STAT3在Tyr705位点的磷酸化导致TFEB介导的自噬-溶酶体通路功能障碍,进而引起大鼠缺血性损伤。
期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-023-04792-x
Yueyang Liu ,Xiaohang Che ,Xiangnan Yu ,Hanxiao Shang ,Peirui Cui ,Xiaoxiao Fu ,Xianda Lu ,Yuhuan Liu ,Chunfu Wu ,Jingyu Yang
自噬
Rat
信号转导
磷酸化
JAK/STAT
TFEB
STAT3