日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Self-clustering of three CBX2 molecules drives PRC2 to promote facultative heterochromatinization of Polycomb target genes.

三个 CBX2 分子的自聚集驱动 PRC2 促进 Polycomb 靶基因的兼性异染色质化。

Ingersoll Steven, Trouth Abby, Angel J Carlos, Luo Xinlong, Espinoza Axel, Wen Joey, Zhu Chengjie, Tucker Joseph, Astatike Kalkidan, Phiel Christopher J, Sabaawy Hatim, Kutateladze Tatiana G, Wu Tao P, Yao Tingting, Lu Chao, Ramachandran Srinivas, Ren Xiaojun

CBX2 phase-separation contributes to homologous recombination repair and drug resistance in ovarian cancer.

CBX2 相分离有助于卵巢癌的同源重组修复和耐药性。

Sun Si, Huang Lin, Ma Yujia, Wei Zheng, Zhu Mengna, Chen Mengqing, Ying Feiquan, Zhou Xiaoling, Yang Ping, Wen Yiping, Yang Qiang, Cai Liqiong, Zhang Yuan, Cai Jing

CBX2 promotes cisplatin resistance in ovarian cancer via SIAH2-mediated β-catenin stabilization and ATG9B-dependent autophagy activation.

CBX2 通过 SIAH2 介导的 β-catenin 稳定和 ATG9B 依赖的自噬激活促进卵巢癌的顺铂耐药性。

CBX2 promoted oral squamous cell carcinoma via increasing CEP55/NF-κB/METTL3/SHP2 signaling induced metastasis/proliferation and angiogenesis.

CBX2 通过增加 CEP55/NF-κB/METTL3/SHP2 信号传导诱导转移/增殖和血管生成,促进口腔鳞状细胞癌的发生发展。

Cuproptosis-related ceRNA axis triggers cell proliferation and cell cycle through CBX2 in lung adenocarcinoma

铜凋亡相关ceRNA轴通过CBX2触发肺腺癌中的细胞增殖和细胞周期

Wu, Jiang; Fu, Guang; Luo, Chao; Chen, Liang; Liu, Quanxing

Sparse CBX2 nucleates many Polycomb proteins to promote facultative heterochromatinization of Polycomb target genes

稀疏的CBX2使许多Polycomb蛋白成核,从而促进Polycomb靶基因的兼性异染色质化

Steven Ingersoll, Abby Trouth, Xinlong Luo, Axel Espinoza, Joey Wen, Joseph Tucker, Kalkidan Astatike, Christopher J Phiel, Tatiana G Kutateladze, Tao P Wu, Srinivas Ramachandran, Xiaojun Ren

Prognostic hub gene CBX2 drives a cancer stem cell-like phenotype in HCC revealed by multi-omics and multi-cohorts

多组学和多队列研究揭示,预后关键基因CBX2驱动肝细胞癌中癌症干细胞样表型

Meng, Qingren; Zhou, Qian; Chen, Xi; Chen, Jun

Cell type-specific role of CBX2 and its disordered region in spermatogenesis

CBX2及其紊乱区域在精子发生过程中的细胞类型特异性作用

Jongmin J Kim ,Emma R Steinson ,Mei Sheng Lau ,Dirk G de Rooij ,David C Page ,Robert E Kingston

Decursinol Angelate Inhibits Glutamate Dehydrogenase 1 Activity and Induces Intrinsic Apoptosis in MDR-CRC Cells

天使酸苯海拉明抑制谷氨酸脱氢酶 1 活性并诱导 MDR-CRC 细胞内在凋亡

Sukkum Ngullie Chang, Sun Chul Kang

PIC recruitment by synthetic reader-actuators to polycomb-silenced genes blocks triple-negative breast cancer invasion

合成读取器执行器将 PIC 募集到多梳沉默基因中,从而阻断三阴性乳腺癌的侵袭

Natecia L Williams, Lauren Hong, Maya Jaffe, Cara E Shields, Karmella A Haynes