日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Geometry-driven immunomodulation in 3D-printed bioceramics: Negative curvature promotes macrophage M2 polarization via Ras-MAPK/HIF-1α signaling for vascularized osteogenesis.

几何形状驱动的 3D 打印生物陶瓷免疫调节：负曲率通过 Ras-MAPK/HIF-1α 信号传导促进巨噬细胞 M2 极化，从而促进血管化骨生成。

期刊:Bioactive Materials
影响因子:20.3
doi:10.1016/j.bioactmat.2026.01.001
Lu Qiji, Kuang Yudi, Diao Jingjing, Zheng Jiaqian, Zhao Naru, Du Chang, Wang Yingjun
细胞生物学
巨噬细胞
RAS
Mapk
MAPK/ERK
巨噬细胞
发表日期：2026
文献求助 收藏

Targeting the Mapk13-Tcf1-Slc7a5 Axis via One-Carbon Metabolic Regulation to Prevent Chronic Allograft Vasculopathy.

通过单碳代谢调节靶向 Mapk13-Tcf1-Slc7a5 轴来预防慢性同种异体移植血管病变。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202520815
Yi Wang, Wu Di, Liu Jing, Chen Shi, Song Liu, Xie Bin, Xie Aini, Lan Peixiang, Chen Zhishui
代谢
Mapk
MAPK/ERK
发表日期：2026
文献求助 收藏

High-throughput drug screening identifies EGFR/MAPK pathway targeting sensitivities in organoid models of ovarian carcinosarcoma.

高通量药物筛选确定卵巢癌肉瘤类器官模型中 EGFR/MAPK 通路靶向敏感性。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-025-03629-8
Farrell Andrew, Dall Genevieve, Vandenberg Cassandra J, Shield-Artin Kristy, Kyran Elizabeth L, Blackmore Tim, Lim Ratana, Taylor Rachael, Neagle Chloe, Ratnayake Gayanie, Tan Tao, Mouradov Dmitri, Hadla Anthony, Jarman Kate, Beard Sally, Jarratt Andrew, Penington Jocelyn S, Wakefield Matthew J, Papenfuss Anthony T, Scott Clare L, Barker Holly E
卵巢癌
信号转导
EGF
EGFR
Mapk
MAPK/ERK
3D/类器官
发表日期：2026
文献求助 收藏

Suppression of ASNS expression by VHL-mediated ubiquitination hinders the progression of renal cell carcinoma through enhancing JUP expression and inhibiting PI3K-AKT and MAPK pathways.

VHL介导的泛素化抑制ASNS表达，通过增强JUP表达和抑制PI3K-AKT和MAPK通路，阻碍肾细胞癌的进展。

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.129332
Yang Wuping, Liu Tao, Ying Wenwei, Lu Minghao, Xia Dan, Tang Tianyu, Peng Ding
细胞生物学
AKT
VHL
Mapk
ASNS
PI3K/Akt
泛素化
发表日期：2026
文献求助 收藏

Selenoprotein GPX3 regulates NADPH oxidase expression by inhibiting the MAPK signaling pathway and thereby attenuating the inflammatory response in renal ischemia-reperfusion injury.

硒蛋白 GPX3 通过抑制 MAPK 信号通路来调节 NADPH 氧化酶的表达，从而减轻肾脏缺血再灌注损伤中的炎症反应。

期刊:Genes and Diseases
影响因子:9.4
doi:10.1016/j.gendis.2025.101640
Pei Jun, Zhang Jie, Yu Chengjun, Luo Jin, Wen Sheng, Hua Yi, Wei Guanghui
炎症/感染
Mapk
MAPK/ERK
炎症
发表日期：2026
文献求助 收藏

Rice blast pathogen effector AvrPib compromises disease resistance by targeting Raf-like protein kinase OsMAPKKK72 to inhibit MAPK signaling.

水稻稻瘟病病原效应因子 AvrPib 通过靶向 Raf 样蛋白激酶 OsMAPKKK72 抑制 MAPK 信号传导，从而削弱水稻的抗病性。

期刊:Journal of Integrative Plant Biology
影响因子:9.3
doi:10.1111/jipb.70072
Wang Zhanchun, Zhong Guitao, Zhang Beibei, Xie Yilin, Gan Yufan, Tang Dingzhong, Wang Wei
信号转导
Mapk
MAPK/ERK
发表日期：2026
文献求助 收藏

Particulate matter 2.5 promotes bladder cancer cell migration and invasion through the crosstalk between integrin-mediated MAPK/ERK and Wnt/β-catenin pathways.

颗粒物 2.5 通过整合素介导的 MAPK/ERK 和 Wnt/β-catenin 通路之间的相互作用促进膀胱癌细胞的迁移和侵袭。

期刊:Particle and Fibre Toxicology
影响因子:8.2
doi:10.1186/s12989-025-00656-3
Cheng Yung-Ting, Lu Kai-Hsi, Hong Shu-Ying, Chen Chung-Hsin, Huang Chao-Yuan, Kung Hsiu-Ni
膀胱癌
细胞生物学
Mapk
MAPK/ERK
发表日期：2026
文献求助 收藏

The maize mitogen-activated protein kinase kinase kinase gene ZmMAPKKK45 is associated with multiple disease resistance.

玉米丝裂原活化蛋白激酶激酶激酶基因 ZmMAPKKK45 与多种抗病性相关。

期刊:New Phytologist
影响因子:8.1
doi:10.1111/nph.70828
Zhong Tao, Olukolu Bode, Bian Yang, Xue Shang, Wisser Randall J, Ojiambo Peter S, Holland James B, Yang Qin, Balint-Kurti Peter
Mapk
MAPK/ERK
发表日期：2026
文献求助 收藏

Glibenclamide attenuates osteoarthritis by suppressing NLRP3 inflammasome activation in synovial macrophages through the MAPK pathway.

格列本脲通过 MAPK 通路抑制滑膜巨噬细胞中 NLRP3 炎症小体的活化，从而减轻骨关节炎。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-026-07923-7
Ni Jinrong, Zhou Hao, Shen Kai, Xu Hongtao, Wang Jinwen, Liu Jiuxiang, Liu Feng
关节炎
细胞生物学
巨噬细胞
Mapk
LRP3
NLRP3
炎性小体
炎症
巨噬细胞
发表日期：2026
文献求助 收藏

Immune-Enhancement Effects of 6-Methoxykaempferol on Cyclophosphamide-Induced Immunosuppression via Improving Antioxidant Enzyme Expression, NF-κB and MAPK Signaling, and Modulating Gut Microbiome.

6-甲氧基山奈酚通过改善抗氧化酶表达、NF-κB和MAPK信号传导以及调节肠道微生物群，对环磷酰胺诱导的免疫抑制具有免疫增强作用。

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox15030334
Jang Na-Yeon, Jaiswal Varun, Park Miey, Lee Hae-Jeung
微生物学
Mapk
MAPK/ERK
发表日期：2026
文献求助 收藏