日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The repressor Capicua is a barrier to lung tumor development driven by Kras/Trp53 mutations

抑制因子Capicua是Kras/Trp53突变驱动的肺肿瘤发展的屏障。

Irene Ballesteros-González ,Iván Hernández-Navas ,Oksana Brehey ,Carmen G Lechuga ,Marina Salmón ,Morena Scotece ,Ricardo Velasco-Vicente ,Alejandra A Flores-Gómez ,Antonio Cebriá ,Lucía Simón-Carrasco ,Gerardo Jiménez ,Monica Musteanu ,Carmen Guerra ,Orlando Domínguez ,Eduardo Caleiras ,Carmen Blanco-Aparicio ,Tirso Pons ,Irene Ferrer ,Luis Paz-Ares ,Raul Torres-Ruiz ,Sandra Rodríguez-Perales ,Mariano Barbacid ,Matthias Drosten

Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size

NMD和TRP53之间的上位性相互作用控制着祖细胞的维持和大脑大小。

Lin Lin ,Jingrong Zhao ,Naoto Kubota ,Zhelin Li ,Yi-Li Lam ,Lauren P Nguyen ,Lu Yang ,Sheela P Pokharel ,Steven M Blue ,Brian A Yee ,Renee Chen ,Gene W Yeo ,Chun-Wei Chen ,Liang Chen ,Sika Zheng

BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes

BRAF(V600E)突变与Trp53或pTEN缺失共同驱动毛细胞白血病起源于B淋巴细胞。

Jiajun Yap # ,Jimin Yuan # ,Wan Hwa Ng # ,Gao Bin Chen # ,Yuen Rong M Sim ,Kah Chun Goh ,Joey Teo ,Trixie Y H Lim ,Shee Min Goay ,Jia Hao Jackie Teo ,Zhentang Lao ,Paula Lam ,Kanaga Sabapathy ,Jiancheng Hu

Frequent loss of metastatic ability in subclones of Apc, Kras, Tgfbr2, and Trp53 mutant intestinal tumor organoids

Apc、Kras、Tgfbr2 和 Trp53 突变型肠道肿瘤类器官的亚克隆经常丧失转移能力

Atsuya Morita ,Mizuho Nakayama ,Dong Wang ,Kazuhiro Murakami ,Masanobu Oshima

Acute Kidney Injury Instigates Malignant Renal Cell Carcinoma via CXCR2 in Mice with Inactivated Trp53 and Pten in Proximal Tubular Kidney Epithelial Cells

急性肾损伤通过CXCR2诱发近端肾小管上皮细胞中Trp53和Pten失活的小鼠发生恶性肾细胞癌

Xunian Zhou # ,Fei Xiao # ,Hikaru Sugimoto ,Bingrui Li ,Kathleen M McAndrews ,Raghu Kalluri

The KrasG12D;Trp53fl/fl murine model of undifferentiated pleomorphic sarcoma is macrophage dense, lymphocyte poor, and resistant to immune checkpoint blockade

KrasG12D;Trp53fl/fl 小鼠未分化多形性肉瘤模型具有巨噬细胞密度高、淋巴细胞稀少、且对免疫检查点阻断疗法耐药的特点。

Karys M Hildebrand ,Arvind K Singla ,Reid McNeil ,Kayla L Marritt ,Kurt N Hildebrand ,Franz Zemp ,Jahanara Rajwani ,Doha Itani ,Pinaki Bose ,Douglas J Mahoney ,Frank R Jirik ,Michael J Monument

Immunohistochemical Characterization of Sarcomas in Trp53+/- Haploinsufficient Mice

Trp53+/-单倍体不足小鼠肉瘤的免疫组织化学特征

M P Jokinen ,D L Morgan ,H C Price ,R A Herbert ,T Saddler ,D Dixon