日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An animal model of NLRC4-associated autoinflammation and infantile enterocolitis reveals novel therapeutic strategies

NLRC4相关自身炎症和婴儿肠炎的动物模型揭示了新的治疗策略

Yuhang Wang ,Joyce Z Gao ,Prajwal Gurung ,Sarah P Short ,Yiqin Xiong ,Scott W Canna ,Zizhen Kang

Pyroptosis of pulmonary fibroblasts and macrophages through NLRC4 inflammasome leads to acute respiratory failure

肺成纤维细胞和巨噬细胞通过NLRC4炎症小体介导的细胞焦亡导致急性呼吸衰竭。

Yan Zhang ,Guoying Zhang ,Brittany Dong ,Ankit Pandeya ,Jian Cui ,Samuel Dos Santos Valenca ,Ling Yang ,Jiaqian Qi ,Zhuodong Chai ,Congqing Wu ,Daniel Kirchhofer ,Toshihiko Shiroishi ,Fadi Khasawneh ,Min Tao ,Feng Shao ,Christopher M Waters ,Yinan Wei ,Zhenyu Li

Integrated NLRP3, AIM2, NLRC4, Pyrin inflammasome activation and assembly drive PANoptosis

NLRP3、AIM2、NLRC4 和 Pyrin 炎症小体的整合激活和组装驱动 PANoptosis

SuHyeon Oh # ,Jihye Lee # ,Jueun Oh ,Gyoengju Yu ,Haesun Ryu ,Daesik Kim ,SangJoon Lee

Salmonella enterica Serovar Typhimurium Induces NAIP/NLRC4- and NLRP3/ASC-Independent, Caspase-4-Dependent Inflammasome Activation in Human Intestinal Epithelial Cells

鼠伤寒沙门氏菌在人肠上皮细胞中诱导不依赖于NAIP/NLRC4和NLRP3/ASC、但依赖于Caspase-4的炎症小体激活

Nawar Naseer ,Jenna Zhang ,Renate Bauer ,David A Constant ,Timothy J Nice ,Igor E Brodsky ,Isabella Rauch ,Sunny Shin

NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses

NLRC4抑制NLRP3炎症小体并消除有效的抗真菌CD8+ T细胞反应

Camila O S Souza ,Natália Ketelut-Carneiro ,Cristiane M Milanezi ,Lúcia H Faccioli ,Luiz G Gardinassi ,João S Silva

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation

IRF8 调控 Naips 的转录以激活 NLRC4 炎症小体

Rajendra Karki ,Ein Lee ,David Place ,Parimal Samir ,Jayadev Mavuluri ,Bhesh Raj Sharma ,Arjun Balakrishnan ,R K Subbarao Malireddi ,Rechel Geiger ,Qifan Zhu ,Geoffrey Neale ,Thirumala-Devi Kanneganti

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface

NLRC4 中的自身炎症突变揭示了富含亮氨酸重复序列 (LRR)-LRR 寡聚化界面

Fiona Moghaddas ,Ping Zeng ,Yuxia Zhang ,Heike Schützle ,Sebastian Brenner ,Sigrun R Hofmann ,Reinhard Berner ,Yuanbo Zhao ,Bingtai Lu ,Xiaoyun Chen ,Li Zhang ,Suyun Cheng ,Stefan Winkler ,Kai Lehmberg ,Scott W Canna ,Peter E Czabotar ,Ian P Wicks ,Dominic De Nardo ,Christian M Hedrich ,Huasong Zeng ,Seth L Masters

Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis

NLRP3、NLRP1、NLRC4 和 AIM2 炎症小体增强介导的细胞因子分泌和甲状腺滤泡细胞焦亡与自身免疫性甲状腺炎相关

Qingling Guo ,Ying Wu ,Yuanyuan Hou ,Yongping Liu ,Tingting Liu ,Hao Zhang ,Chenling Fan ,Haixia Guan ,Yushu Li ,Zhongyan Shan ,Weiping Teng

NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease

MRP8+细胞中NAIP/NLRC4炎症小体的激活足以引起全身性炎症性疾病。

Randilea D Nichols ,Jakob von Moltke ,Russell E Vance

Obesity-associated NLRC4 inflammasome activation drives breast cancer progression

肥胖相关的NLRC4炎症小体激活驱动乳腺癌进展

Ryan Kolb ,Liem Phan ,Nicholas Borcherding ,Yinghong Liu ,Fang Yuan ,Ann M Janowski ,Qing Xie ,Kathleen R Markan ,Wei Li ,Matthew J Potthoff ,Enrique Fuentes-Mattei ,Lesley G Ellies ,C Michael Knudson ,Mong-Hong Lee ,Sai-Ching J Yeung ,Suzanne L Cassel ,Fayyaz S Sutterwala ,Weizhou Zhang