CCL22相关文献与解析，生知库 | 链接生命科学的每一步

Filatov, Ekaterina; Sasaki, Shugo; Haque, Manjurul; Kar, Saumadritaa; Fung, Vivian C W; Mojibian, Majid; Krentz, Nicole A J; MacDonald, Katherine N; Salim, Kevin; Soukhatcheva, Galina; Dai, Derek L; Orban, Paul C; Verchere, C Bruce; Levings, Megan K; Lynn, Francis C

发育与干细胞

T细胞

CCL2

VISTA expressed on tumor cells is regulated by m6A and influences immune microenvironment through STAT3/CCL22 in NSCLC.

VISTA 在肿瘤细胞上表达，受 m6A 调控，并通过 STAT3/CCL22 影响非小细胞肺癌的免疫微环境。

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-06818-3

Xu Hao, Shen Kaikai, Jiang Bei, Xu Qiuli, Li Bingbing, Ke Zhangmin, Cheng Qinpei, Zhu Suhua, Wang Dong, Song Yong, Lv Tangfeng

The chemokines CCL22 and CCL17 are a defining feature of type 2 stimulated human lung macrophages and exhibit different metabolic dependencies

趋化因子CCL22和CCL17是2型免疫球蛋白刺激的人肺巨噬细胞的标志性特征，并表现出不同的代谢依赖性。

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2025.1654717.

Amanda J L Ridley ,Annabel J Curle ,Stefano A P Colombo ,Joshua J Hughes ,Douglas P Dyer ,Angela Simpson ,Lee M Booty ,Maria Feeney ,Peter C Cook ,Andrew S MacDonald

Macrophage fatty acid metabolism under chronic hypoxia shapes γδ T cell recruitment via CCL22

慢性缺氧条件下巨噬细胞脂肪酸代谢通过CCL22影响γδ T细胞的募集

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2025.113025

Vanesa M Guerrero Ruiz ,Aya Khabaza ,Rebekka Bauer ,Blerina Aliraj ,Siavash Mansouri ,Sofie P Meyer ,Megan A Palmer ,Hauke Winter ,Laura V Klotz ,Mohammed A F Elewa ,Ivan M Kur ,Carlo Angioni ,Rahmat Mojaradfar ,Lisa Hahnefeld ,Rajkumar Savai ,Dominik Fuhrmann ,Andreas Weigert ,Bernhard Brüne

The CCL17/CCL22-CCR4 Axis in Pain Pathogenesis: A Comprehensive Review of Immune-Mediated Mechanisms and Therapeutic Opportunities

CCL17/CCL22-CCR4轴在疼痛发病机制中的作用：免疫介导机制和治疗机会的全面综述

期刊:Molecular Neurobiology

影响因子:4.3

doi:10.1007/s12035-025-05550-9

Hasheminia, Amin; Mann, Sarah; Liblik, Kiera; El-Diasty, Mohammad

IRF3 Promotes Production of IL-6 and Nitric Oxide but Represses CCL22 in RAW264.7 Macrophage Cells Exposed to Lipopolysaccharides in Culture

在体外培养中，当RAW264.7巨噬细胞暴露于脂多糖时，IRF3促进IL-6和一氧化氮的产生，但抑制CCL22的表达。

期刊:Journal of Inflammation Research

影响因子:4.1

doi:10.2147/JIR.S496930

Moore, Tyler C; Pinkerton, Terrence Scott; Petro, Thomas M

CCL22 as a diagnostic and prognostic biomarker for pediatric-onset systemic lupus erythematosus

CCL22 作为儿童期发病系统性红斑狼疮的诊断和预后生物标志物

期刊:Clinical and Experimental Medicine

影响因子:3.5

doi:10.1007/s10238-025-01790-0

Chen, Xiao-Lin; Liu, Chen-Xi; Huang, Meng-Ke; Hui, Lu; Liu, Ting; Jiang, Yong-Mei

Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially control regulatory T cell phenotype and function via CXCL9 and CCL22

小鼠胰腺肿瘤中呈递抗原的癌相关成纤维细胞通过 CXCL9 和 CCL22 对调节性 T 细胞的表型和功能进行差异性调控。

期刊:

影响因子:

doi:10.1101/2025.03.27.645833

Maru, Saumya Y; Wetzel, Meredith; Mitchell, Jacob T; Gross, Nicole E; Andaloori, Lalitya; Howe, Kathryn; Kartalia, Emma; Mo, Guanglan; Leatherman, James; Ho, Won Jin; Fertig, Elana J; Kagohara, Luciane T; Pearce, Edward J; Jaffee, Elizabeth M

Tumor cells upregulate CCL22 in a STING-dependent manner in response to paracrine factors released by STING-activated myeloid cells and type I interferons.

肿瘤细胞在 STING 激活的髓系细胞和 I 型干扰素释放的旁分泌因子的作用下，以 STING 依赖的方式上调 CCL22。

期刊:Immunohorizons

影响因子:

doi:10.1093/immhor/vlaf048

Lomashvili Elmira M, Kim Jihyun, Kong Lingwei, Cook Pamela R

Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure

巨噬细胞衍生的趋化因子CCL22可建立局部淋巴结介导的适应性产热和能量消耗。

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adn5229

Yexian Yuan ，Ruoci Hu ，Jooman Park ，Shaolei Xiong ，Zilai Wang ，Yanyu Qian ，Zuoxiao Shi ，Ruifan Wu ，Zhenbo Han ，Sang-Ging Ong ，Shuhao Lin ，Krista A Varady ，Pingwen Xu ，Daniel C Berry ，Gang Shu ，Yuwei Jiang

CCL22-expressing Stem Cell-derived Islet Grafts Recruit Regulatory T Cells in Mice

表达CCL22的干细胞衍生胰岛移植可在小鼠体内募集调节性T细胞

VISTA expressed on tumor cells is regulated by m6A and influences immune microenvironment through STAT3/CCL22 in NSCLC.

VISTA 在肿瘤细胞上表达，受 m6A 调控，并通过 STAT3/CCL22 影响非小细胞肺癌的免疫微环境。

The chemokines CCL22 and CCL17 are a defining feature of type 2 stimulated human lung macrophages and exhibit different metabolic dependencies

趋化因子CCL22和CCL17是2型免疫球蛋白刺激的人肺巨噬细胞的标志性特征，并表现出不同的代谢依赖性。

Macrophage fatty acid metabolism under chronic hypoxia shapes γδ T cell recruitment via CCL22

慢性缺氧条件下巨噬细胞脂肪酸代谢通过CCL22影响γδ T细胞的募集

The CCL17/CCL22-CCR4 Axis in Pain Pathogenesis: A Comprehensive Review of Immune-Mediated Mechanisms and Therapeutic Opportunities

CCL17/CCL22-CCR4轴在疼痛发病机制中的作用：免疫介导机制和治疗机会的全面综述

IRF3 Promotes Production of IL-6 and Nitric Oxide but Represses CCL22 in RAW264.7 Macrophage Cells Exposed to Lipopolysaccharides in Culture

在体外培养中，当RAW264.7巨噬细胞暴露于脂多糖时，IRF3促进IL-6和一氧化氮的产生，但抑制CCL22的表达。

CCL22 as a diagnostic and prognostic biomarker for pediatric-onset systemic lupus erythematosus

CCL22 作为儿童期发病系统性红斑狼疮的诊断和预后生物标志物

Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially control regulatory T cell phenotype and function via CXCL9 and CCL22

小鼠胰腺肿瘤中呈递抗原的癌相关成纤维细胞通过 CXCL9 和 CCL22 对调节性 T 细胞的表型和功能进行差异性调控。

Tumor cells upregulate CCL22 in a STING-dependent manner in response to paracrine factors released by STING-activated myeloid cells and type I interferons.

肿瘤细胞在 STING 激活的髓系细胞和 I 型干扰素释放的旁分泌因子的作用下，以 STING 依赖的方式上调 CCL22。

Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure

巨噬细胞衍生的趋化因子CCL22可建立局部淋巴结介导的适应性产热和能量消耗。