Structure-guided engineering of CCL27 enhances natural ligand CAR T-cells against CCR10 for multiple myeloma
通过结构导向工程改造 CCL27，增强天然配体 CAR T 细胞对抗 CCR10 的疗效，用于治疗多发性骨髓瘤。
期刊:
影响因子:
doi:10.1101/2025.08.19.670119
Chilakapati, Nikhil; Patiño-Escobar, Bonell; Chen, Emily Y; Dalal, Radhika; de Montagnac, Jonathan; Johnson, Haley; Kang, Amrik S; Akagi, Naomi; Ramos, Emilio; Phojanakong, Paul; Salangsang, Fernando; Zeng, Yan; Chari, Ajai; Chung, Alfred; Kumar, Anupama D; Martin, Thomas G; Wolf, Jeffrey L; Shy, Brian R; Steri, Veronica; Karlon, William J; Kortemme, Tanja; Barwick, Benjamin G; Wiita, Arun P
细胞生物学
CR1
CCL27
多发性骨髓瘤
骨髓瘤
CCL2
T细胞
