SIRT6相关文献与解析，生知库 | 链接生命科学的每一步

Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesity

小胶质细胞Sirt6通过调节NRF2的转录活性来改善高脂饮食诱导的肥胖。

Xiaoxia Xiao ,Huiling Hu ,Yadi Zhong ,Yingjian Chen ,Kaijia Tang ,Zhisen Pan ,Jiawen Huang ,Xiaoying Yang ,Qi Wang ,Yong Gao

代谢

Sirt6 Activation Ameliorates Inflammatory Bone Loss in Ligature-Induced Periodontitis in Mice

Sirt6激活可改善小鼠结扎诱导牙周炎中的炎症性骨丢失

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms241310714

Myung Jin Lee ，Hyang Hwa Ryu ，Jae Won Hwang ，Jung Ryul Kim ，Eui-Sic Cho ，Jin Kyeong Choi ，Young Jae Moon

Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression

Sirt6通过CREB依赖的Sox6抑制作用将肌纤维重编程为氧化型

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-022-29472-5

Mi-Young Song # ，Chang Yeob Han # ，Young Jae Moon ，Ju Hyung Lee ，Eun Ju Bae ，Byung-Hyun Park

CREB

发表日期：2022

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Sirt6-mediated epigenetic modification of DNA accessibility is essential for Pou2f3-induced thymic tuft cell development

Sirt6介导的DNA可及性表观遗传修饰对于Pou2f3诱导的胸腺簇细胞发育至关重要。

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-022-03484-9

Qian Zhang # ，Jiayu Zhang # ，Tong Lei # ，Zhanfeng Liang ，Xue Dong ，Liguang Sun ，Yong Zhao

SIRT6 stabilization and cytoplasmic localization in macrophages regulates acute and chronic inflammation in mice

巨噬细胞中SIRT6的稳定性和胞质定位调控小鼠的急性和慢性炎症。

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2022.101711

Mariana Bresque ，Karina Cal ，Valentina Pérez-Torrado ，Laura Colman ，Jorge Rodríguez-Duarte ，Cecilia Vilaseca ，Leonardo Santos ，María Pía Garat ，Santiago Ruiz ，Frances Evans ，Rosina Dapueto ，Paola Contreras ，Aldo Calliari ，Carlos Escande

SIRT6 promotes mitochondrial fission and subsequent cellular invasion in ovarian cancer

SIRT6促进卵巢癌中线粒体分裂和随后的细胞侵袭

期刊:FEBS Open Bio

影响因子:2.8

doi:10.1002/2211-5463.13452

Shreya Bandopadhyay ,Parash Prasad ,Upasana Ray ,Damayanti Das Ghosh ,Sib Sankar Roy

Flow Cytometry Analysis of SIRT6 Expression in Peritoneal Macrophages

流式细胞术分析腹腔巨噬细胞中SIRT6的表达

期刊:Bio-protocol

影响因子:1

doi:10.21769/BioProtoc.4523

Valentina Pérez-Torrado ，Jorge Rodríguez-Duarte ，Carlos Escande ，Mariana Bresque

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis

碱基切除/单链断裂修复蛋白复合物的组装/解离的时间动态受PARP/NAD+/SIRT6轴调控。

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2021.109917

Christopher A Koczor ,Kate M Saville ,Joel F Andrews ,Jennifer Clark ,Qingming Fang ,Jianfeng Li ,Rasha Q Al-Rahahleh ,Md Ibrahim ,Steven McClellan ,Mikhail V Makarov ,Marie E Migaud ,Robert W Sobol

Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance

Sirt6 调控髓质胸腺上皮细胞的发育，并有助于建立中枢免疫耐受。

期刊:Frontiers in Cell and Developmental Biology

影响因子:4.6

doi:10.3389/fcell.2021.655552

Qian Zhang ，Zhanfeng Liang ，Jiayu Zhang ，Tong Lei ，Xue Dong ，Huiting Su ，Yifang Chen ，Zhaoqi Zhang ，Liang Tan ，Yong Zhao

PKCδ Regulates DNA Damage and Cell Death through a SIRT6/Nrf2-dependent Antioxidant Response

PKCδ 通过 SIRT6/Nrf2 依赖的抗氧化反应调节 DNA 损伤和细胞死亡

Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesity

小胶质细胞Sirt6通过调节NRF2的转录活性来改善高脂饮食诱导的肥胖。

Sirt6 Activation Ameliorates Inflammatory Bone Loss in Ligature-Induced Periodontitis in Mice

Sirt6激活可改善小鼠结扎诱导牙周炎中的炎症性骨丢失

Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression

Sirt6通过CREB依赖的Sox6抑制作用将肌纤维重编程为氧化型

Sirt6-mediated epigenetic modification of DNA accessibility is essential for Pou2f3-induced thymic tuft cell development

Sirt6介导的DNA可及性表观遗传修饰对于Pou2f3诱导的胸腺簇细胞发育至关重要。

SIRT6 stabilization and cytoplasmic localization in macrophages regulates acute and chronic inflammation in mice

巨噬细胞中SIRT6的稳定性和胞质定位调控小鼠的急性和慢性炎症。

SIRT6 promotes mitochondrial fission and subsequent cellular invasion in ovarian cancer

SIRT6促进卵巢癌中线粒体分裂和随后的细胞侵袭

Flow Cytometry Analysis of SIRT6 Expression in Peritoneal Macrophages

流式细胞术分析腹腔巨噬细胞中SIRT6的表达

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis

碱基切除/单链断裂修复蛋白复合物的组装/解离的时间动态受PARP/NAD+/SIRT6轴调控。

Sirt6 Regulates the Development of Medullary Thymic Epithelial Cells and Contributes to the Establishment of Central Immune Tolerance

Sirt6 调控髓质胸腺上皮细胞的发育，并有助于建立中枢免疫耐受。