PIP相关文献与解析，生知库 | 链接生命科学的每一步

Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway

Piezo1通过RhoA/ROCK1/PIP2信号通路调控肌动蛋白细胞骨架重塑，从而驱动宫颈癌细胞发生EMT。

期刊:Discover Oncology

影响因子:2.8

doi:10.1007/s12672-025-02474-7

Juexiao Deng # ,Yang Li # ,Lanyue Zhang # ,Wenxin Liao ,Tingting Liu ,Fujin Shen

Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface

开放的KATP通道结构揭示了串联的PIP2结合位点，这些位点介导了Kir6.2和SUR1的调控界面。

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-024-46751-5.

Camden M Driggers ,Yi-Ying Kuo ,Phillip Zhu ,Assmaa ElSheikh ,Show-Ling Shyng

PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation

PSTPIP2通过抑制白细胞介素-19介导的中性粒细胞胞外陷阱形成来改善马兜铃酸肾病

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.89740

Changlin Du # ，Chuanting Xu # ，Pengcheng Jia ，Na Cai ，Zhenming Zhang ，Wenna Meng ，Lu Chen ，Zhongnan Zhou ，Qi Wang ，Rui Feng ，Jun Li ，Xiaoming Meng ，Cheng Huang ，Taotao Ma

Molecular basis of product recognition during PIP5K-mediated production of PI(4,5)P2 with positive feedback

PIP5K介导的PI(4,5)P2生成过程中产物识别的分子基础及其正反馈机制

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1016/j.jbc.2024.107631

Benjamin R Duewell ,Katherine A Faris ,Scott D Hansen

发表日期：2024

文献求助收藏

Inhibition of the proton-activated chloride channel PAC by PIP2

PIP2对质子激活氯离子通道PAC的抑制作用

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.83935

Ljubica Mihaljević # ,Zheng Ruan # ,James Osei-Owusu ,Wei Lü ,Zhaozhu Qiu

发表日期：2023

文献求助收藏

Molecular interactions of adaptor protein PSTPIP2 control neutrophil-mediated responses leading to autoinflammation

衔接蛋白PSTPIP2的分子相互作用控制中性粒细胞介导的反应，从而导致自身炎症

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2022.1035226

Nataliia Pavliuchenko ，Iris Duric ，Jarmila Kralova ，Matej Fabisik ，Frantisek Spoutil ，Jan Prochazka ，Petr Kasparek ，Jana Pokorna ，Tereza Skopcova ，Radislav Sedlacek ，Tomas Brdicka

Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux

磷脂酰肌醇4,5-二磷酸（PIP2）促进去甲肾上腺素转运蛋白二聚化并调节底物外排

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-022-04210-1

Dino Luethi ,Julian Maier ,Deborah Rudin ,Dániel Szöllősi ,Thomas J F Angenoorth ,Stevan Stankovic ,Matthias Schittmayer ,Isabella Burger ,Jae-Won Yang ,Kathrin Jaentsch ,Marion Holy ,Anand Kant Das ,Mario Brameshuber ,Gisela Andrea Camacho-Hernandez ,Andrea Casiraghi ,Amy Hauck Newman ,Oliver Kudlacek ,Ruth Birner-Gruenberger ,Thomas Stockner ,Gerhard J Schütz ,Harald H Sitte

免疫/内分泌

发表日期：2022

文献求助收藏

PIP2 promotes the incorporation of CD43, PSGL-1, and CD44 into nascent HIV-1 particles

PIP2促进CD43、PSGL-1和CD44整合到新生HIV-1颗粒中

VCPIP1 facilitates pancreatic adenocarcinoma progression via Hippo/YAP signaling

VCPIP1通过Hippo/YAP信号通路促进胰腺腺癌进展

Disruption of Morrbid alleviates autoinflammatory osteomyelitis in Pstpip2-deficient mice

Morrbid 的破坏可减轻 Pstpip2 缺陷小鼠的自身炎症性骨髓炎

Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway

Piezo1通过RhoA/ROCK1/PIP2信号通路调控肌动蛋白细胞骨架重塑，从而驱动宫颈癌细胞发生EMT。

Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface

开放的KATP通道结构揭示了串联的PIP2结合位点，这些位点介导了Kir6.2和SUR1的调控界面。

PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation

PSTPIP2通过抑制白细胞介素-19介导的中性粒细胞胞外陷阱形成来改善马兜铃酸肾病

Molecular basis of product recognition during PIP5K-mediated production of PI(4,5)P2 with positive feedback

PIP5K介导的PI(4,5)P2生成过程中产物识别的分子基础及其正反馈机制

Inhibition of the proton-activated chloride channel PAC by PIP2

PIP2对质子激活氯离子通道PAC的抑制作用

Molecular interactions of adaptor protein PSTPIP2 control neutrophil-mediated responses leading to autoinflammation

衔接蛋白PSTPIP2的分子相互作用控制中性粒细胞介导的反应，从而导致自身炎症

Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux

磷脂酰肌醇4,5-二磷酸（PIP2）促进去甲肾上腺素转运蛋白二聚化并调节底物外排