日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sintilimab and anlotinib with gemcitabine plus cisplatin in advanced biliary tract cancer: SAGC a randomized phase 2 trial

信迪利单抗和安罗替尼联合吉西他滨和顺铂治疗晚期胆道癌:SAGC 一项随机 II 期试验

Jingjing Li # ,Shurui Zhou # ,Xiaoqing Xu # ,Qinhong Zheng # ,Fabiao Zhang ,Cong Luo ,Da Li ,Xing Sun ,Zhe Han ,Wei Wu ,Junrong Yan ,Yang Shao ,Yuhua Zhang ,Bingchen Wu ,Qing Wei ,Xinbao Wang ,Yiwen Zhou ,Weijing Sun ,Qi Xu ,Jieer Ying

The Smoothened agonist SAG Modulates the Male and Female Peripheral Immune Systems Differently in an Immune Model of Central Nervous System Demyelination

Smoothened激动剂SAG在中枢神经系统脱髓鞘免疫模型中对男性和女性外周免疫系统的调节作用不同

Abdelmoumen Kassoussi ,Amina Zahaf ,Tom Hutteau-Hamel ,Claudia Mattern ,Michael Schumacher ,Pierre Bobé ,Elisabeth Traiffort

Serum IL-5 levels predict HBsAg seroclearance in patients treated with Nucleos(t)ide analogues combined with pegylated interferon

血清IL-5水平可预测接受核苷(酸)类似物联合聚乙二醇干扰素治疗的患者的HBsAg血清清除情况

Peipei Wang ,Zhishuo Mo ,Ying Zhang ,Chunxia Guo ,Trevor Kudzai Chikede ,Dabiao Chen ,Ziying Lei ,Zhiliang Gao ,Qian Zhang ,Qiaoxia Tong

A glycoengineered therapeutic anti-HBV antibody that allows increased HBsAg immunoclearance improves HBV suppression in vivo

一种经糖基化改造的治疗性抗HBV抗体,可增强HBsAg的免疫清除,从而改善体内HBV抑制效果。

Min You # ,Fentian Chen # ,Chao Yu # ,Yuanzhi Chen ,Yue Wang ,Xue Liu ,Xueran Guo ,Bing Zhou ,Xin Wang ,Boya Zhang ,Mujin Fang ,Tianying Zhang ,Ping Yue ,Yingbin Wang ,Quan Yuan ,Wenxin Luo

Predictive value of Th17 and Treg cells at baseline for HBsAg loss in chronic hepatitis B patients with low HBsAg quantification treated with pegylated interferon and nucleos(t)ide analogue

基线时 Th17 和 Treg 细胞对接受聚乙二醇干扰素和核苷(酸)类似物治疗的低 HBsAg 定量慢性乙型肝炎患者 HBsAg 消失的预测价值

Li-Li Wu ,Xiao-Yan Li ,Kai Deng ,Bing-Liang Lin ,Hong Deng ,Dong-Ying Xie ,Geng-Lin Zhang ,Qi-Yi Zhao ,Zhi-Shuo Mo ,Yue-Hua Huang ,Zhi-Liang Gao

Antisense-mediated repression of SAGA-dependent genes involves the HIR histone chaperone

反义介导的 SAGA 依赖性基因抑制涉及 HIR 组蛋白伴侣。

Julien Soudet ,Nissrine Beyrouthy ,Anna Marta Pastucha ,Andrea Maffioletti ,Dario Menéndez ,Zahra Bakir ,Françoise Stutz

D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with Remdesivir

D,L-赖氨酸-乙酰水杨酸酯+甘氨酸(LASAG)可降低SARS-CoV-2复制,并与瑞德西韦产生叠加效应

Johannes Jungwirth ,Clio Häring ,Sarah König ,Liane Giebeler ,Heena Doshi ,Christian Brandt ,Stefanie Deinhardt-Emmer ,Bettina Löffler ,Christina Ehrhardt

HBsAg-specific CD8+ T cells as an indispensable trigger to induce murine hepatocellular carcinoma

HBsAg特异性CD8+ T细胞是诱导小鼠肝细胞癌的必要触发因素

Xiaolei Hao ,Yongyan Chen ,Lu Bai ,Haiming Wei ,Rui Sun ,Zhigang Tian

Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

在TNL受体免疫中,NRG1与EDS1和SAG101的关联依赖于病原体效应子的识别,这种关联是NRG1与EDS1和SAG101相互作用的结果。

Xinhua Sun # ,Dmitry Lapin # ,Joanna M Feehan # ,Sara C Stolze ,Katharina Kramer ,Joram A Dongus ,Jakub Rzemieniewski ,Servane Blanvillain-Baufumé ,Anne Harzen ,Jaqueline Bautor ,Paul Derbyshire ,Frank L H Menke ,Iris Finkemeier ,Hirofumi Nakagami ,Jonathan D G Jones ,Jane E Parker

The SAGA complex regulates early steps in transcription via its deubiquitylase module subunit USP22

SAGA复合物通过其去泛素化酶模块亚基USP22调控转录的早期步骤。

Timothy J Stanek ,Victoria J Gennaro ,Mason A Tracewell ,Daniela Di Marcantonio ,Kristen L Pauley ,Sabrina Butt ,Christopher McNair ,Feng Wang ,Andrew V Kossenkov ,Karen E Knudsen ,Tauseef Butt ,Stephen M Sykes ,Steven B McMahon