CD200相关文献与解析，生知库 | 链接生命科学的每一步

Increased soluble CD200 in serum of SLE patients does not reflect disease activity or affect CD200R1 function in T cells

SLE患者血清中可溶性CD200水平升高并不反映疾病活动度，也不影响T细胞中CD200R1的功能。

期刊:Arthritis Research & Therapy

影响因子:4.6

doi:10.1186/s13075-026-03782-1

Kaan, Ellen D; Verburg, Fabienne; Limper, Maarten; Meyaard, Linde; van der Vlist, Michiel

Peripheral CD200R signaling: A critical regulator of post-stroke inflammation in aged mice.

外周 CD200R 信号传导：老年小鼠中风后炎症的关键调节因子。

期刊:Brain Research Bulletin

影响因子:3.7

doi:10.1016/j.brainresbull.2025.111686

Ngwa Conelius, Misrani Afzal, Xu Yan, Wang Jingjing, Ritzel Rodney, Liu Fudong

Therapeutic exploration of combined local hyperthermia and anti-CD200 blockade therapy in the EMT6 breast cancer model

在EMT6乳腺癌模型中探索局部热疗联合抗CD200阻断疗法的治疗效果

期刊:Medical Oncology

影响因子:3.5

doi:10.1007/s12032-026-03240-7

Wan Mohd Zawawi, Wan Fatin Amira; Loh, Kar Min; Abdul Wahab, Asnida; Mohd Salim, Maheza Irna; Jemon, Khairunadwa

Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study

Ucenprubart 是一种 CD200R 激动性抗体，具有治疗炎症性皮肤病的潜力：临床前开发和 I 期临床研究

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-59147-w

Anja Koester ，Derrick R Witcher ，Mark Lee ，Stephen J Demarest ，Scott Potter ，Katie Werle ，Scott Bauer ，Diana Ruiz ，Laurent Malherbe ，Josh Poorbaugh ，Andrew Glasebrook ，Christoph Preuss ，Gourab Datta ，Ziqiao Wang ，Jack Knorr ，David Manner ，Dipak Patel ，Carsten Schmitz ，Paul Klekotka ，Ajay Nirula

Apolipoprotein E is a marker of all chondrocytes in the growth plate resting zone

载脂蛋白E是生长板静止区所有软骨细胞的标志物。

期刊:Bone Research

影响因子:14.3

doi:10.1038/s41413-025-00407-2

Joe Kodama ，Takeshi Oichi ，Kevin J Wilkinson ，Joshua M Abzug ，Takashi Kaito ，Motomi Enomoto-Iwamoto ，Masahiro Iwamoto ，Satoru Otsuru

细胞生物学

发表日期：2025

文献求助收藏

Comprehensive transcriptome sequencing and biochemical studies revealed that acrolein induced lung injury in BEAS-2B cells and male rats through the lncRNA MIR155HG/miR-155-5p/CD200R1 and Nrf2/SLC7A11/GPX4 ferroptosis pathways

全面的转录组测序和生化研究表明，丙烯醛通过lncRNA MIR155HG/miR-155-5p/CD200R1和Nrf2/SLC7A11/GPX4铁死亡通路诱导BEAS-2B细胞和雄性大鼠的肺损伤。

期刊:Redox Biology

影响因子:11.9

doi:10.1016/j.redox.2025.103832

Liu, Dan; Yu, Hui; Liu, Zhicun; Wang, Le; Liu, Dawo; Cao, Xiangyu

CD200R blockade enhances anti-tumor immunity by unleashing NK and CD8(+) T cells in tumor

CD200R阻断通过激活肿瘤中的NK细胞和CD8(+) T细胞来增强抗肿瘤免疫力。

期刊:Acta Pharmacologica Sinica

影响因子:8.4

doi:10.1038/s41401-025-01556-0

Zhang, Zheng-Feng; Zhang, Yu; Chen, Ya-Wen; Cao, Guo-Shuai; Zheng, Xiao-Dong; Sun, Rui; Peng, Hui; Tian, Zhi-Gang; Sun, Hao-Yu

CD200 immune checkpoint expression is associated with inferior outcome in multiple myeloma patients treated with anti-CD38 monoclonal antibodies

CD200免疫检查点表达与接受抗CD38单克隆抗体治疗的多发性骨髓瘤患者的不良预后相关

期刊:Oncoimmunology

影响因子:6.3

doi:10.1080/2162402X.2025.2532226

Chemlal, Djamila; Pochard, Camille; Jacquier, Valentin; Bruyer, Angélique; Gabellier, Ludovic; Fornero, Léa; Vempère, Clément; Machura, Amélie; Requirand, Guilhem; Robert, Nicolas; Bret, Caroline; Cartron, Guillaume; Vincent, Laure; de Boussac, Hugues; Moreaux, Jérôme; Herbaux, Charles

Bone marrow mesenchymal stem cells alleviate smoke inhalation injury by regulating alveolar macrophage polarization via the CD200-CD200R pathway.

骨髓间充质干细胞通过 CD200-CD200R 通路调节肺泡巨噬细胞极化，从而减轻吸入烟雾造成的损伤。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1645460

Ding Ziling, Zhuang Yong, Zhao Yunlong, Shi Jie, Guo Xiaoqin, Fan Haojun, Lv Qi

C/EBPÎ² Contributes to Cancer-Induced Bone Pain by Inhibiting CD200/CD200R1 in the Spinal Cord.

C/EBPβ通过抑制脊髓中的CD200/CD200R1，导致癌症引起的骨痛。

Increased soluble CD200 in serum of SLE patients does not reflect disease activity or affect CD200R1 function in T cells

SLE患者血清中可溶性CD200水平升高并不反映疾病活动度，也不影响T细胞中CD200R1的功能。

Peripheral CD200R signaling: A critical regulator of post-stroke inflammation in aged mice.

外周 CD200R 信号传导：老年小鼠中风后炎症的关键调节因子。

Therapeutic exploration of combined local hyperthermia and anti-CD200 blockade therapy in the EMT6 breast cancer model

在EMT6乳腺癌模型中探索局部热疗联合抗CD200阻断疗法的治疗效果

Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study

Ucenprubart 是一种 CD200R 激动性抗体，具有治疗炎症性皮肤病的潜力：临床前开发和 I 期临床研究

Apolipoprotein E is a marker of all chondrocytes in the growth plate resting zone

载脂蛋白E是生长板静止区所有软骨细胞的标志物。

Comprehensive transcriptome sequencing and biochemical studies revealed that acrolein induced lung injury in BEAS-2B cells and male rats through the lncRNA MIR155HG/miR-155-5p/CD200R1 and Nrf2/SLC7A11/GPX4 ferroptosis pathways

全面的转录组测序和生化研究表明，丙烯醛通过lncRNA MIR155HG/miR-155-5p/CD200R1和Nrf2/SLC7A11/GPX4铁死亡通路诱导BEAS-2B细胞和雄性大鼠的肺损伤。

CD200R blockade enhances anti-tumor immunity by unleashing NK and CD8(+) T cells in tumor

CD200R阻断通过激活肿瘤中的NK细胞和CD8(+) T细胞来增强抗肿瘤免疫力。

CD200 immune checkpoint expression is associated with inferior outcome in multiple myeloma patients treated with anti-CD38 monoclonal antibodies

CD200免疫检查点表达与接受抗CD38单克隆抗体治疗的多发性骨髓瘤患者的不良预后相关

Bone marrow mesenchymal stem cells alleviate smoke inhalation injury by regulating alveolar macrophage polarization via the CD200-CD200R pathway.

骨髓间充质干细胞通过 CD200-CD200R 通路调节肺泡巨噬细胞极化，从而减轻吸入烟雾造成的损伤。