日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome writing and Targeted Delivery of the NKX6-3/ANK1 gene cluster and its Type 2 Diabetes GWAS Variants to Human iPSCs.

将 NKX6-3/ANK1 基因簇及其 2 型糖尿病 GWAS 变异体进行基因组写入和靶向递送至人类 iPSCs。

NKX6-3 in B-Cell Progenitor Differentiation and Leukemia

NKX6-3 在 B 细胞祖细胞分化和白血病中的作用

Nagel, Stefan; Meyer, Corinna; Pommerenke, Claudia

Deletion of RFX6 impairs iPSC-derived islet organoid development and survival, with no impact on PDX1(+)/NKX6.1(+) progenitors

RFX6基因缺失会损害iPSC来源的胰岛类器官的发育和存活,但对PDX1(+)/NKX6.1(+)祖细胞没有影响。

Aldous, Noura; Elsayed, Ahmed K; Memon, Bushra; Ijaz, Sadaf; Hayat, Sikander; Abdelalim, Essam M

Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell volume in human subjects

在人体受试者中,α细胞中NKX6.1表达增加和ARX表达减少伴随着β细胞体积的减少。

Fujita, Yukari; Kozawa, Junji; Fukui, Kenji; Iwahashi, Hiromi; Eguchi, Hidetoshi; Shimomura, Iichiro

NKX6.1 transcription factor: a crucial regulator of pancreatic β cell development, identity, and proliferation

NKX6.1转录因子:胰岛β细胞发育、特性和增殖的关键调控因子

Aigha, Idil I; Abdelalim, Essam M

Genetic and phenotypic characterization of NKX6-2-related spastic ataxia and hypomyelination

NKX6-2相关痉挛性共济失调和髓鞘发育不良的遗传和表型特征

Chelban, V; Alsagob, M; Kloth, K; Chirita-Emandi, A; Vandrovcova, J; Maroofian, R; Davagnanam, I; Bakhtiari, S; AlSayed, M D; Rahbeeni, Z; AlZaidan, H; Malintan, N T; Johannsen, J; Efthymiou, S; Ghayoor Karimiani, E; Mankad, K; Al-Shahrani, S A; Beiraghi Toosi, M; AlShammari, M; Groppa, S; Haridy, N A; AlQuait, L; Qari, A; Huma, R; Salih, M A; Almass, R; Almutairi, F B; Hamad, M H; Alorainy, I A; Ramzan, K; Imtiaz, F; Puiu, M; Kruer, M C; Bierhals, T; Wood, N W; Colak, D; Houlden, H; Kaya, N

NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer

NKX6.1抑制结直肠癌的肿瘤发生、转移和化疗耐药性

Hsin-Hua Chung,Chun-Te Lee,Je-Ming Hu,Yu-Ching Chou,Ya-Wen Lin ,Yu-Lueng Shih

Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism

基于全基因组基因分析的减肥干预措施揭示了NKX6.3在代谢中的潜在作用

Valsesia, Armand; Wang, Qiao-Ping; Gheldof, Nele; Carayol, Jérôme; Ruffieux, Hélène; Clark, Teleri; Shenton, Victoria; Oyston, Lisa J; Lefebvre, Gregory; Metairon, Sylviane; Chabert, Christian; Walter, Ondine; Mironova, Polina; Lau, Paulina; Descombes, Patrick; Viguerie, Nathalie; Langin, Dominique; Harper, Mary-Ellen; Astrup, Arne; Saris, Wim H; Dent, Robert; Neely, Greg G; Hager, Jörg

Correction to: Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1

更正:增强人类多能干细胞向共表达PDX1和NKX6.1的胰腺祖细胞的分化

Memon, Bushra; Karam, Manale; Al-Khawaga, Sara; Abdelalim, Essam M

Multiple genetic mutations caused by NKX6.3 depletion contribute to gastric tumorigenesis

NKX6.3 缺失导致的多种基因突变促进胃肿瘤的发生

Yoon, Jung Hwan; Kim, Olga; Eun, Jung Woo; Choi, Sung Sook; Ashktorab, Hassan; Smoot, Duane T; Nam, Suk Woo; Park, Won Sang