日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Screening of a quinonoid compounds library identifies decylubiquinone as an antioxidant and anti-apoptotic agent against glucocorticoid-induced osteoporosis via CD39/CD73/adenosine axis.

对醌类化合物库的筛选发现癸基泛醌是一种抗氧化剂和抗凋亡剂，可通过 CD39/CD73/腺苷轴对抗糖皮质激素诱导的骨质疏松症。

期刊:Bioactive Materials
影响因子:20.3
doi:10.1016/j.bioactmat.2026.03.062
Xu Yu, Xu Wenpeng, Zhang Wencan, Li Shangzhi, Zhang Dingxin, Lin Xiangyu, Sun Qian, Wang Yanguo, Hu Peijie, Si Haipeng
骨质疏松
表观遗传
CD3
CD7
CD73
CD39
凋亡
发表日期：2026
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Fluorine-18-Labeled Nucleotide Analogs Targeting Ecto-5'-Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

用于实体瘤正电子发射断层扫描成像的靶向胞外5'-核苷酸酶（CD73）的氟-18标记核苷酸类似物

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202522758
Dobelmann, Clemens; Schmies, Constanze C; Rolshoven, Georg Wilhelm; Scortichini, Mirko; Wagner, Stefan; Isaak, Andreas; Idris, Riham M; Dabel, Jennifer; Grey, Lucie; Losenkova, Karolina; Moschütz, Susanne; Hroub, Haneen Al; Keim, Antje; Höppner, Sandra; Sandholm, Jouko; Boström, Pia; Hollmén, Maija; Sträter, Norbert; Hermann, Sven; Yegutkin, Gennady G; Jacobson, Kenneth A; Schelhaas, Sonja; Müller, Christa E; Junker, Anna
CD7
CD73
发表日期：2026
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Overcoming EGFR-Mediated Dendritic Cell Dysfunction to Enhance Anti-tumor Immunity in EGFR-Mutant NSCLC by Precisely Targeting CD73 With pH-responsive Nanocarriers

利用pH响应纳米载体精确靶向CD73，克服EGFR介导的树突状细胞功能障碍，增强EGFR突变型非小细胞肺癌的抗肿瘤免疫力

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202513182
Shang, Xiaoling; Geng, Xudong; Wang, Zixu; Yuan, Shumin; Ding, Shanshan; Liu, Ni; Ma, Xinchun; Sun, Xuan; Wang, Huimin; Sun, Ying; Qu, Xun; Ren, Guangwen; Li, Yong Qiang; Wang, Xiuwen; Liu, Yanguo
肺癌
肿瘤
CD7
肿瘤免疫
树突状细胞
CD73
EGF
EGFR
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2026
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CD73 blockade enhances antitumor efficacy of oHSV in solid tumors by increasing macrophage-mediated antigen presentation

CD73阻断通过增强巨噬细胞介导的抗原呈递，提高oHSV在实体瘤中的抗肿瘤疗效。

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2025-013640
Murphy, Sara A; Li, Jiaqi; Sahu, Upasana; Swanner, Jessica; Lewis, Cole T; Anchang, Benedict; Cui, Yan; Chiocca, E Antonio; Kaur, Balveen
巨噬细胞
肿瘤
CD7
肿瘤免疫
巨噬细胞
CD73
细胞生物学
免疫/内分泌
发表日期：2026
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CAR-T cells with the CD38(-)CD73(-)Tim-3(-)HLA-DR(+) phenotype predict the efficacy of tisagenlecleucel as a treatment for B cell precursor ALL.

具有 CD38(-)CD73(-)Tim-3(-)HLA-DR(+) 表型的 CAR-T 细胞可预测 tisagenlecleucel 作为 B 细胞前体 ALL 治疗药物的疗效。

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2025.102576
Mikami Takashi, Kato Itaru, Llamas-Covarrubias Mara Anais, Hiramatsu Hidefumi, Uchihara Yoshinori, Mitsuyoshi Takaya, Kitawaki Toshio, Saida Satoshi, Umeda Katsutsugu, Ogawa Seishi, Takaori-Kondo Akifumi, Wing James Badger, Takita Junko
CD7
T细胞
CD73
CD3
CD38
细胞生物学
发表日期：2026
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Sym024 Interacts with a Unique Epitope on the CD73 Homodimer, Favoring Effective Bivalent Binding to Improve Anti-PD-1 Therapy.

Sym024 与 CD73 同源二聚体上的独特表位相互作用，有利于有效的二价结合，从而改善抗 PD-1 疗法。

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-2406
Jakobsen Janus S, Grandal Michael M, Hansen Randi W, Bansia Harsh, Armbruster Emily, Theret Isabelle, Skartved Niels Jørgen Ø, Hald Rikke, Melander Maria C, Worsaae Anne, Riva Matteo, Reckzeh Kristian, Vuillard Laurent, Lantto Johan, des Georges Amedee, Fröhlich Camilla
CD73
CD7
PD-1
发表日期：2026
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CD73 overexpression in ADSCs accelerates bladder repair by regulating the NFκB/NLRP3/caspase-1 signaling axis in neurogenic bladder rats

ADSCs中CD73的过表达通过调节神经源性膀胱大鼠的NFκB/NLRP3/caspase-1信号通路加速膀胱修复

期刊:npj Regenerative Medicine
影响因子:6.5
doi:10.1038/s41536-026-00454-1
Zhu, Guanqun; Zhang, Rui; Huang, Jiao; Zhang, Zongliang; Zhao, Kai; Yin, Xinbao; Yang, Xiaokun; Jiang, Zaiqing; Yang, Han; Bae, Woong Jin; Wang, Ke
CD7
信号转导
CD73
Rat
LRP3
NLRP3
发表日期：2026
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Contrasting functions of CD73 and adenosine in CD8+ T-cell exhaustion during antitumor immunity.

CD73 和腺苷在抗肿瘤免疫过程中 CD8+ T 细胞耗竭中的相反作用。

期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2026.2642458
细胞生物学
肿瘤
免疫/内分泌
CD7
CD8
CD73
肿瘤免疫
发表日期：2026
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CD73 restrains mutant β-catenin oncogenic activity in endometrial carcinomas

CD73抑制子宫内膜癌中突变β-catenin的致癌活性

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.189510
Hirsch, Rebecca M; Droby, Gaith; Premsankar, Sunthoshini; Parrish, Molly L; Kurnit, Katherine C; Chiou, Lilly F; Rabjohns, Emily M; Lee, Hannah N; Broaddus, Russell R; Vaziri, Cyrus; Bowser, Jessica L
肿瘤免疫
肿瘤
CD73
子宫内膜癌
CD7
发表日期：2026
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Oncostatin M upregulates CD73 via the MAPK pathway in keratinocytes to promote an adenosine-dependent anti-inflammatory response in psoriasis

抑癌素M通过MAPK通路上调角质形成细胞中的CD73，从而促进银屑病中腺苷依赖性抗炎反应。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2026.1698290
Giraulo, Caterina; De Palma, Giacomo; Plaitano, Paola; Esposito, Roberta; Morretta, Elva; Monti, Maria Chiara; Müller, Christa E; Cicala, Carla; Morello, Silvana
肿瘤
CD7
肿瘤免疫
信号转导
CD73
银屑病
MAPK/ERK
细胞生物学
发表日期：2026
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