日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacogenomic profiling of ABCB1 and CES1 in atrial fibrillation patients on dabigatran from a multiethnic Malaysian cohort

马来西亚多民族人群中接受达比加群治疗的房颤患者的ABCB1和CES1药物基因组学分析

Tan, Shirley Siang Ning; Sim, Edmund Ui-Hang; Jinam, Timothy Adrian; Lim, Melissa Siaw Han; Chee, Cassandra Sheau Mei; Anchah, Lawrence; Rosli, Saiful Shakirin; Sateng, Beatrice Bangie Desmond; Gerunsin, Jerry; Tiong, Lee Len; Fong, Alan Yean Yip

Variant-to-Biomarker Integration and Mechanistic Validation Identify CES1 as a Copy Number-Linked Predictor of Radiotherapy Response in Rectal Cancer

变异体与生物标志物整合及机制验证表明,CES1是直肠癌放射治疗反应的拷贝数相关预测因子

Yang, Xiaodong; Zheng, Mingye; Lu, Xiaoxia; Li, Yongxiang

Functional regulation of macrophages by Ces1d-mediated lipid signaling in immunometabolism

Ces1d介导的脂质信号在免疫代谢中对巨噬细胞的功能调控

Long J Shao ,Fathima Elizondo ,Feng Gao ,Rabie Habib ,Xin Li ,Katherine Pham ,Jazmin Ysaguirre ,Maryam Elizondo ,Shirindokht Shirazi ,Kristin L Eckel-Mahan ,Sean Hartig ,Huaizhu Wu ,Kai Sun

Hypercholesterolemia and the role of lipid metabolism gene CES1 in immune infiltration promote central nervous system relapse in acute myeloid leukemia

高胆固醇血症和脂质代谢基因CES1在免疫浸润中的作用促进急性髓系白血病中枢神经系统复发

Bao, Wanwan; Tu, Yansong; Zhang, Shan; Jiang, Xiaoyan; Chen, Huijun; Tu, Huaijun; Li, Jian

Discovery of lignans as the effective inhibitors of CES1A alleviate lipid droplets formation

木脂素作为CES1A的有效抑制剂,被发现能够缓解脂滴的形成。

Mu, Jie; Chen, Si-Si; Li, Shi-Qing; Jin, Qiang; Geng, Jin; Zou, Li-Wei

CES1 Increases Hepatic Triacylglycerol Synthesis Through Activation of PPARγ, LXR and SREBP1c.

CES1 通过激活 PPARα、LXR 和 SREBP1c 增加肝脏三酰甘油的合成。

Selvaraj Rajakumar, Lian Jihong, Watts Russell, Nelson Randal, Saikali Michael F, Cummins Carolyn L, Lehner Richard

Confounding Effect of Hepatic Carboxylesterase 1 (CES1) Variability on Clopidogrel Oxidation

肝羧酸酯酶1 (CES1) 变异对氯吡格雷氧化的混杂效应

Subash, Sandhya; Singh, Dilip K; Khojasteh, S Cyrus; Murray, Bernard P; Zientek, Michael A; Jones, Robert S; Kulkarni, Priyanka; Smith, Bill J; Prasad, Bhagwat

The role of ABCB1 and CES1 genotypes on the efficacy and safety of dabigatran: a systematic review and meta-analysis

ABCB1和CES1基因型对达比加群疗效和安全性的影响:系统评价和荟萃分析

Aldiban, Weam; Hamam, Nada G; Almosilhy, Nereen A; Elsamman, Kholoud; Wagdy, Mohamed; Mashaly, Doaa; Batarseh, Suhel F; El-Sherif, Youssef; Khalefa, Basma Badrawy; Otmani, Zina

Transcriptomics and Targeted Metabolomics Reveal That CES1 Ablation in Macrophages Confers a Distinct Inflammatory Phenotype Involving Altered Interleukin-1β, Citrate, and Lipid Levels.

转录组学和靶向代谢组学揭示巨噬细胞中 CES1 的缺失赋予了其独特的炎症表型,涉及白细胞介素-1β、柠檬酸盐和脂质水平的改变。

Adekanye Oluwabori, Borazjani Abdolsamad, Phillips Maggie E, Ross Matthew K

Mechanistic insights into human carboxylesterase 2 (CES2) inhibition by the CES1 prodrug substrate remdesivir

瑞德西韦作为CES1前药底物,其抑制人羧酸酯酶2 (CES2) 的机制研究

Pentyala, Abhinav; Kandel, Sylvie E; Lampe, Jed N