日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.

在免疫选择的背景下,CRISPR 筛选发现 CHD1 和 MAP3K7 是癌症免疫疗法耐药性的介质。

Watterson Alex, Picco Gabriele, Veninga Vivien, Samarakoon Youhani, Cattaneo Chiara M, Vieira Sara F, Karakoc Emre, Bhosle Shriram, Battaglia Thomas W, Consonni Sarah, Halim Timotheus Y F, Voest Emile E, Garnett Mathew J, Coelho Matthew A

Mutant CHCHD10 disrupts cytochrome c oxidation and activates mitochondrial retrograde signaling.

突变体 CHCHD10 破坏细胞色素 c 氧化并激活线粒体逆行信号传导。

Campos-Ribeiro Márcio Augusto, Donnarumma Erminia, Nolte Hendrik, Cobine Paul, Vimont Elodie, Milenkovic Dusanka, Hernandez-Camacho Juan Diego, Langa-Vives Francina, Kornobis Etienne, Pénard Esthel, Yde Sonny, Langer Thomas, Paquis-Flucklinger Véronique, Wai Timothy

Genetic loss of CHD1 regulates distinct histone post-translational modifications in the development of castration-resistant prostate cancer

CHD1基因缺失调控去势抵抗性前列腺癌发展过程中不同的组蛋白翻译后修饰

Purohit, Tanaya A; Gawdzik, Joseph; Armstrong, Eric A; Yang, Bing; Schultz, Zachery; Bahr, Kayla; Do, Truman J; Machhi, Rehaan; Sardeson, Sean; Rizvi, Mohammad; Nakada, Sarah A; Singh, Anupama; Esbona, Karla; Huang, Wei; Roskes, Marjorie L; Khurana, Ekta; Lewis, Peter W; Denu, John M; Jarrard, David F

Cord Blood DNA Methylation at CHD13 Is Associated with Adiponectin Levels at 10 to 14 Years of Age

脐带血中CHD13位点的DNA甲基化与10至14岁时的脂联素水平相关

Bianco, Monica E; Gurra, Miranda G; Scholtens, Denise M; Hivert, Marie-France; Lowe, William L Jr; Josefson, Jami L

FDA-approved PDE4 inhibitors alleviate the dominant toxicity of ALS-FTD-associated CHCHD10(S59L) in Drosophila and human cells.

FDA 批准的 PDE4 抑制剂可减轻 ALS-FTD 相关 CHCHD10(S59L) 在果蝇和人类细胞中的主要毒性。

Maitra Swati, Ham Do-Won, Baek Minwoo, Choe Yun-Jeong, Kim Nam Chul

CHD1L promotes testicular cancer progression through epigenetic activation of the CXCR6/PI3K/AKT pathway

CHD1L通过表观遗传激活CXCR6/PI3K/AKT通路促进睾丸癌进展。

Zhao, Yang; Yan, Hao; Chen, Xinda; Zhang, Xiaolin; Lu, Mujun; Zhang, Ming

SMCHD1 loss re-wires MYOD1 enhancer nexuses and chromatin accessibility landscapes in muscle cells

SMCHD1 缺失重塑肌肉细胞中 MYOD1 增强子连接和染色质可及性格局

Huang, Zhijun; Cui, Wei; Klaiss, Adam; Pfeifer, Gerd P

Structural basis of human CHD1 nucleosome recruitment and pausing

人类CHD1核小体募集和暂停的结构基础

Allison M James ,Lucas Farnung

Disrupted transcriptional networks regulated by CHD1L during neurodevelopment underlie the mirrored neuroanatomical and growth phenotypes of the 1q21.1 copy number variant.

神经发育过程中由 CHD1L 调控的转录网络紊乱是 1q21.1 拷贝数变异体所表现出的镜像神经解剖学和生长表型的基础。

Lemée Marianne Victoria, Loviglio Maria Nicla, Ye Tao, Tilly Peggy, Keime Céline, Weber Chantal, Petrova Anastasiya, Klein Pernelle, Morlet Bastien, Wendling Olivia, Jacobs Hugues, Tharreau Mylène, Geneviève David, Godin Juliette D, Romier Christophe, Duteil Delphine, Golzio Christelle

CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential

CHD1L 在癌症及其他领域中的作用:结构、致癌功能和治疗潜力

Clune, Sophia; Awolade, Paul; Esquer, Hector; Zhou, Qiong; LaBarbera, Daniel V