日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Oligodendrocyte Precursor Cells Shape Retinogeniculate Refinement Via a CHD8-Dependent Phagocytic Pathway.

少突胶质细胞前体细胞通过 CHD8 依赖性吞噬途径塑造视网膜-膝状体精细化。

Wen Siyue, Guo Fengru, Li Zhidan, Huang Guojiao, Shen Minghe, He Xuelian

Single-cell delineation of the microbiota-gut-brain axis: Probiotic intervention in Chd8 haploinsufficient mice

单细胞层面解析肠道菌群-肠-脑轴:益生菌干预Chd8单倍体不足小鼠

Peifeng Ji ,Ning Wang ,You Yu ,Junjie Zhu ,Zhenqiang Zuo ,Bing Zhang ,Fangqing Zhao

CHD8 interacts with BCL11A to induce oncogenic transcription in triple negative breast cancer

CHD8 与 BCL11A 相互作用,诱导三阴性乳腺癌中的致癌转录

Mark Waterhouse #,Kyren Lazarus #,Maria Francesca Santolla #,Sara Pensa,Eleanor Williams,Abigail J Q Siu,Hisham Mohammed,Irina Mohorianu,Marcello Maggiolini,Jason Carroll,Laura S Itzhaki,Taufiq Rahman,Walid T Khaled

Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development.

小鼠皮层发育过程中,由于 Chd8 单倍体不足导致细胞类型特异性基因表达失调。

Yim Kristina M, Baumgartner Marybeth, Krenzer Martina, Rosales Larios María F, Hill-Terán Guillermina, Nottoli Timothy, Muhle Rebecca A, Noonan James P

CHD8 adulthood microglial knockdown in C57BL6 mice induces behavioral, morphological, and transcriptional changes in a sex-dependent manner.

在 C57BL6 小鼠中敲低 CHD8 成年小胶质细胞会以性别依赖的方式诱导行为、形态和转录变化。

Kismet/CHD7/CHD8 affects gut microbiota, mechanics, and the gut-brain axis in Drosophila melanogaster

Kismet/CHD7/CHD8 基因影响果蝇的肠道菌群、肠道力学以及肠-脑轴。

Niosi, Angelo; Võ, Nguyên Henry; Sundaramurthy, Punithavathi; Welch, Chloe; Penn, Aliyah; Yuldasheva, Yelena; Alfareh, Adam; Rausch, Kaitlyn; Amin-Rahbar, Takhmina; Cavanaugh, Jeffery; Yadav, Prince; Peterson, Stephanie; Brown, Raina; Hu, Alain; Ardon-Castro, Any; Nguyen, Darren; Crawford, Robert; Lee, Wendy; Morris, Eliza J; Jensen, Mikkel Herholdt; Mulligan, Kimberly

Identification of Therapeutic Targets in Autism Spectrum Disorder through CHD8-Notch Pathway Interaction Analysis

通过CHD8-Notch通路相互作用分析识别自闭症谱系障碍的治疗靶点

Zhang, Hewei; Hua, Shenghao; Jiao, Daiyan; Chen, Dong; Gu, Qin; Bao, Chao

Phenotypic Variability and Paternal Inheritance of a CHD8 Variant Causing Intellectual Developmental Disorder With Autism and Macrocephaly Confirmed by Epigenetic and Structural Analyses

通过表观遗传学和结构分析证实,CHD8变异体导致智力发育障碍伴自闭症和巨头畸形的表型变异性和父系遗传

Furuta, Yutaka; Ezell, Kimberly M; Hamid, Rizwan; Cogan, Joy D; Cassini, Thomas A; Rives, Lynette; McMinn, Ashley; Shah, Shailee; Peltier, Amanda C; Layfield, Stephen; Fletcher, Robin S; Tedder, Matthew L; Louie, Raymond J; Lee, Jennifer A; Kerkhof, Jennifer; Rzasa, Jessica; Sadikovic, Bekim; Al Mamun, Abdullah; Sheehan, Jonathan H; Moth, Christopher W; Meiler, Jens; Vawter-Lee, Marissa; Mendoza-Sengco, Paola Maria; Holzen, Jennifer B; Pruthi, Sumit; Phillips, John A 3rd; Tinker, Rory J

Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient mice.

成年 Chd8 单倍体不足小鼠持续存在皮层兴奋性神经元功能失调。

CHD8-related disorders redefined: an expanding spectrum of dystonic phenotypes

重新定义 CHD8 相关疾病:肌张力障碍表型谱的扩展

Sorrentino, Ugo; Boesch, Sylvia; Doummar, Diane; Ravelli, Claudia; Serranova, Tereza; Indelicato, Elisabetta; Winkelmann, Juliane; Burglen, Lydie; Jech, Robert; Zech, Michael