Anti-Caspase-3 antibody [E87] (Ab32351)
CPP32, CASP3, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CPP-32, SCA-1
用户验证的应用
推荐稀释比例
- IHC-P1/25 - 1/100 Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.
- WB1/5000
- ICC/IF1 µg/mL For unpurified, use 1/25 dilution.
- Flow Cyt (Intra)1/180 - 1/1000 ab199376 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
- IP1/10 - 1/50
详细信息
背景信息
Anti-Caspase-3 antibody [E87] (ab32351) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in human samples. Anti-Caspase-3 antibody [E87] (ab32351) has been cited over 386 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Caspase-3 antibody [E87] (ab32351) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Caspase-3 antibody [E87] (ab32351) has been confirmed by testing in knockout samples. Anti-Caspase-3 antibody [E87] (ab32351) has 11 independent reviews from customers. Anti-Caspase-3 antibody [E87] (ab32351) specifically detects Caspase-3 (UniProt ID: P42574; Molecular weight: 17kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone E87 - ab197202. Antibody clone E87 is also available pre-conjugated to a variety of labels for your convenience - Biotin, PE, APC, HRP, Alkaline Phosphatase, Alexa Fluor® 488, Alexa Fluor® 647, Alexa Fluor® 594 ( ab195905, ab305665, ab305666, ab305667, ab308706, ab309678, ab310040, ab310425 ). Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (587)
A Novel FGFR3-Targeting Antibody-Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS-STING Pathway in Bladder Cancer.
一种新型的FGFR3靶向抗体-药物偶联物通过cGAS-STING通路诱导膀胱癌细胞凋亡。
Spatially selective clearance of inflammation-mediated reactive oxygen species in injured kidney cells.
空间选择性清除受损肾细胞中炎症介导的活性氧。
Lactate-driven ATP6V1B2 lactylation triggers asthmatic inflammation by linking lysosomal dysfunction to mitochondrial ROS-dependent pyroptosis.
乳酸驱动的 ATP6V1B2 乳酸化通过将溶酶体功能障碍与线粒体 ROS 依赖性细胞焦亡联系起来,从而引发哮喘炎症。
Aptamer-functionalized exosomes combined with doxorubicin suppress GBM progression and enhance chemoradiosensitivity by promoting pyroptosis.
适体功能化的外泌体与阿霉素联合使用,通过促进细胞焦亡抑制胶质母细胞瘤进展并增强化疗和放射敏感性。
Unfolded Protein Response as a Therapeutic Target: 4-(Heptyloxy)phenol Induces Programmed Cell Death in Ewing Sarcoma.
未折叠蛋白反应作为治疗靶点:4-(庚氧基)苯酚诱导尤文氏肉瘤细胞程序性死亡。
Omega-3 Fatty Acids Attenuate LPS-Induced Acute Kidney Injury via Activation of AMPK/SIRT1/PGC-1α/NRF2/FOXO3 Signaling and Suppression of NF-κB-Mediated Inflammation.
Omega-3 脂肪酸通过激活 AMPK/SIRT1/PGC-1α/NRF2/FOXO3 信号通路和抑制 NF-κB 介导的炎症来减轻 LPS 诱导的急性肾损伤。
Interleukin-17A Orchestrates Lung Injury and Remodeling Through p53 and uPA System Crosstalk.
白细胞介素-17A通过p53和uPA系统相互作用来调控肺损伤和重塑。
Leptin Regulates Intervertebral Disc Calcification and Ossification by Promoting Glycolysis Through OCN/HIF-1α Axis.
瘦素通过 OCN/HIF-1α 轴促进糖酵解,从而调节椎间盘钙化和骨化。
Cycloastragenol Inhibits Colorectal Cancer Cell Metastasis via Epithelial-Mesenchymal Transition and the PI3K Signalling Pathway.
环阿斯特拉醇通过上皮-间质转化和PI3K信号通路抑制结直肠癌细胞转移。
Synergistic effects through targeting the PI3K and IGFR pathways in treating lung cancer carrying activation alterations along the PI3K pathway.
通过靶向 PI3K 和 IGFR 通路发挥协同作用,治疗 PI3K 通路激活改变的肺癌。
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