Anti-CD68 antibody [ED1] (Ab31630)

特异性

ab31630 recognises a single chain glycoprotein of 110kD that is expressed predominantly on the lysosomal membrane of myeloid cells. Weak cell surface expression also occurs. The antigen is expressed by the majority of tissue macrophages and weakly by peripheral blood granulocytes. Studies have shown that the antigen recognised by ED1 is the rat homologue of human CD68.

Product Specifications Anti-CD68 antibody [ED1] (ab31630) is a mouse monoclonal antibody and is validated for use in Flow Cyt (Intra) in rat samples. Anti-CD68 antibody [ED1] (ab31630) specifically detects CD68 (UniProt ID: P34810; Molecular weight: 35kDa) and is sold in 125 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CD68 antibody [ED1] (ab31630) has high sensitivity and specificity. Anti-CD68 antibody [ED1] (ab31630) has been cited over 403 times in peer reviewed journals and is trusted by the scientific community. Anti-CD68 antibody [ED1] (ab31630) has 20 independent reviews from customers. Target Information CD68 is a transmembrane glycoprotein predominantly expressed on macrophages, playing a crucial role in phagocytosis and antigen presentation. It is involved in various pathological conditions, including neuroinflammatory diseases, where it helps clear cellular debris and modulate immune response. CD68 expression is associated with several diseases, particularly those involving macrophage activity, including, cancer, neuroinflammation, Granular cell tumor and histiocytic sarcoma. This product should be stored undiluted.