Anti-TBR1 antibody (Ab31940)
T-box brain protein 1, T-brain-1, TBR-1, TES-56, TBR1
详细信息
背景信息
Anti-TBR1 antibody (ab31940) is a rabbit polyclonal antibody and is validated for use in IHC-P, WB. Anti-TBR1 antibody (ab31940) has been cited over 476 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-TBR1 antibody (ab31940) has high sensitivity and specificity. Anti-TBR1 antibody (ab31940) has 31 independent reviews from customers. Anti-TBR1 antibody (anti-HPRT antibody) (ab31940) specifically detects TBR1 (UniProt ID: Q64336; Molecular weight: 74kDa) and is sold in 100 µg selling sizes. TBR1 (T-Box Brain Transcription Factor 1) is a transcription factor that is crucial for brain development, particularly in the formation of the cerebral cortex. It regulates the expression of genes involved in neuronal differentiation and migration. Mutations in the TBR1 gene are associated with neurodevelopmental disorders, including autism spectrum disorder and intellectual disability, where they disrupt normal brain development and function.
文献引用 (512)
TSC tunes progenitor balance and upper-layer neuron generation in neocortex.
TSC 调节新皮层中的祖细胞平衡和上层神经元生成。
Dynamic subtype- and context-specific subcellular RNA regulation in growth cones of developing neurons of the cerebral cortex.
大脑皮层发育神经元生长锥中动态的亚型和上下文特异性亚细胞RNA调控。
Epilepsy-associated FOXJ3 variants link a transcriptional program of the PTEN-mTOR pathway to neuronal specification and cortical lamination.
与癫痫相关的 FOXJ3 变异将 PTEN-mTOR 通路的转录程序与神经元分化和皮质分层联系起来。
Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC-Derived Cortical Organoids.
自噬激活剂可使异常的 Tau 蛋白稳态正常化，并挽救人类家族性阿尔茨海默病 iPSC 衍生皮质类器官中的突触。
Role for NF-κB in herpes encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity
NF-κB在模拟IRF3-IFN免疫先天缺陷的小鼠疱疹性脑炎病理中的作用
Copper deficiency impairs oligodendrocyte maturation and social behavior via mitophagy and mTOR suppression in ASD.
铜缺乏会通过线粒体自噬和 mTOR 抑制损害 ASD 中的少突胶质细胞成熟和社交行为。
No indication of histological changes in embryonic somatosensory cortex development upon maternal aspartame consumption in mice.
小鼠母体摄入阿斯巴甜后，未发现胚胎体感皮层发育的组织学变化。
Nonsense-mediated mRNA decay orchestrates neuronal migration and cortical lamination while modulating Reelin and ciliary gene regulatory networks.
无义介导的 mRNA 衰变协调神经元迁移和皮层分层，同时调节 Reelin 和纤毛基因调控网络。
Dual developmental effects of ARX poly-alanine mutations on human cortical excitatory and inhibitory neurons.
ARX多聚丙氨酸突变对人类皮层兴奋性和抑制性神经元的双重发育影响。
Akhirin Functions as an Innate Immune Barrier to Preserve Neurogenic Niche Homeostasis During Mouse Brain Development.
Akhirin 在小鼠大脑发育过程中发挥着先天免疫屏障的作用，以维持神经发生微环境的稳态。
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