Anti-Bcl-2 antibody [E17] (Ab32124)

Apoptosis regulator Bcl-2, BCL2

反应种属:Human
抗原名称:BCL2
应用:WB, IHC, IP

用户验证的应用

推荐稀释比例

  • IHC-P1/250 - 1/500 We do not recommend rat and mouse samples with IHC. Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
  • WB1/1000 We recommend using ab182858 for murine samples.
  • IP1/50

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-Bcl-2 antibody [E17]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

What is this antibody validated in? Anti-Bcl-2 antibody [E17] (ab32124) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of Bcl-2? Anti-Bcl-2 [E17] (ab32124) specifically detects a band for Bcl-2 (UniProt: P10415) at a molecular weight of 26kDa. Trusted by the scientific community Anti-Bcl-2 [E17] (ab32124) was first used in a scientific publication in 2006 and has been cited over 1300 times in peer-reviewed journals. Reviewed by scientists Anti-Bcl-2 [E17] (ab32124) has over 10 independent reviews from customers. Specificity confirmed The specificity of Anti-Bcl-2 antibody [E17] (ab32124) has been confirmed by Immunocytochemistry testing in BCL2 Knockout Hap1 cells. Other related products We have a range of other formats of antibody clone [E17] also available for your convenience: ab32124, Carrier free - ab185002, Carrier free - ab242335, Alexa Fluor® 488 - ab311028, Alexa Fluor® 647 - ab311154, Alexa Fluor® 594 - ab311800, Alexa Fluor® 568 - ab313083, Alexa Fluor® 555 - ab313277, Alexa Fluor® 750 - ab321578 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Species reactivity Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.

文献引用 (1360)

A Novel FGFR3-Targeting Antibody-Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS-STING Pathway in Bladder Cancer.

一种新型的FGFR3靶向抗体-药物偶联物通过cGAS-STING通路诱导膀胱癌细胞凋亡。

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1.

TP53BP2 通过 G9a 和 DNMT1 协同调节 E2F1 促进胎盘自噬和先兆子痫。

Integrating single-cell and spatial transcriptomics to dissect mast-cell heterogeneity and arginine-metabolism-associated markers in BRCA.

整合单细胞和空间转录组学来解析 BRCA 中肥大细胞异质性和精氨酸代谢相关标志物。

Gao Mengli, Ran Yuge, Qi Juan, Han Xiao, Wei Yali, Wang Kunjie, Wu Xiaoxi, Sun Chengcheng, Li Yanhong, Wang Wenyan, Xie Wenjie, Zhang Peng, Liu Kuan, Shi Hongyun

Targeted Degradation of Histone Deacetylase 8 Using Proteolysis Targeting Chimeras Technology: A Promising Approach for Glioblastoma Treatment.

利用蛋白水解靶向嵌合体技术靶向降解组蛋白去乙酰化酶 8:一种有前景的胶质母细胞瘤治疗方法。

Chotitumnavee Jiranan, Seemaung Peeratchai, Settacomkul Rapeewan, Sukprasert Ratchanon, Itoh Yukihiro, Suzuki Takayoshi, Srihirun Sirada, Power Christopher, Vivithanaporn Pornpun

Naoxintong capsule decreases circulating exosomes of miR-382-5p to protect LPS-induced vascular endothelial cell injury by targeting STC1 in vitro.

钠心通胶囊通过靶向 STC1 在体外降低循环外泌体中 miR-382-5p 的含量,从而保护 LPS 诱导的血管内皮细胞损伤。

Xu Ziyan, Wu Hao, Fan Weiyang, Meng Fenzhao, Hu Shuangfei, Zou Muhan, Chen Yixuan, Su Weiwei, Li Peibo

Moracin D Inhibits Gastric Cancer Progression Through B-Cell Lymphoma-2 (Bcl-2)-Mediated Cell Cycle Arrest and Apoptosis, Enhancing Chemotherapy Efficacy.

Moracin D 通过 B 细胞淋巴瘤-2 (Bcl-2) 介导的细胞周期阻滞和凋亡抑制胃癌进展,增强化疗疗效。

Moqbel Abdulkareem Qasem, Yang He, Liu Shunhui, Feng Li, Ghani Muhammad Usman, Ke Xiaoxue, Cui Hongjuan

Acacetin Attenuates Lysophosphatidylcholine-Induced Vascular Smooth Muscle Cell Injury via Sirt1-Nrf2/p62 Signaling Axis.

阿卡西汀通过 Sirt1-Nrf2/p62 信号轴减弱溶血磷脂酰胆碱诱导的血管平滑肌细胞损伤。

Li Yun-Da, Wu Yao, Zhou Tian-Li, Yuan Qian, Li Gui-Rong, Wu Wei-Yin, Wang Yan, Li Gang

Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells.

鼠尾草酸介导活性氧的产生,从而调节丝裂原活化蛋白激酶通路磷酸化并诱导人乳腺癌细胞凋亡。

Wang Xinyu, Xu Peng, Luan Sha, Jiao Yuying, Gao Yue, Zhao Changjiu, Fu Peng

Integrated multi-target pharmacology of ginseng in acute myeloid leukemia through single-cell sequencing, molecular docking, network pharmacology, and in vitro experiments.

通过单细胞测序、分子对接、网络药理学和体外实验,研究人参在急性髓系白血病中的综合多靶点药理作用。

Zhang Yan, Su Bo-Bin, Jiao Chang-Qing, Wu Zhong-Hui, Zhou Jun-Jie, Ge Jian

Mesenchymal stem cell-derived miR-125b-1-3p-abundant exosomes alleviate osteoarthritis by modulating the KDM6B-H3K27me3-FOXM1 axis.

间充质干细胞衍生的富含 miR-125b-1-3p 的外泌体通过调节 KDM6B-H3K27me3-FOXM1 轴来缓解骨关节炎。

Liu Xiaoming, Zhou Jun, Chai Bin, Xiao Yongqiang, Li Pingping, Shi Tingting, Cui Rui, Zhang Guoning, Jiang Shuai
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