Anti-Synaptophysin antibody [YE269] - Synaptic Marker (Ab32127)

Synaptophysin, Major synaptic vesicle protein p38, SYP

反应种属:Human, Mouse, Rat
抗原名称:SYP
应用:WB, IHC, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

Anti-Synaptophysin antibody [YE269] (ab32127) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P and WB. Anti-Synaptophysin antibody [YE269] (ab32127) was first used in a scientific publication in 1986 and has been cited over 311 times in peer reviewed journals. It's performance in Western blot and IHC in mouse samplesis trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Synaptophysin antibody [YE269] (ab32127) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Synaptophysin antibody [YE269] (ab32127) has been confirmed by Western Blot testing in Synaptophysin knockout HEK-293T cells ( ab255356 ). Anti-Synaptophysin antibody [YE269] (ab32127) has 38 independent reviews from customers. Anti-Synaptophysin antibody [YE269] (ab32127) specifically detects Synaptophysin (UniProt ID: P08247; Molecular weight: 34kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone YE269 - ab187259. Antibody clone YE269 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor ® 647, Alexa Fluor ® 488, Alexa Fluor ® 594, Alexa Fluor ® 555, ( ab195520, ab196166, ab196379, ab206868, ab206870, ). Synaptophysin (SYP) is a key protein in neuro research, particularly for its role as a marker of synaptic vesicles. It is involved in synaptic transmission and vesicle trafficking. Researchers use synaptophysin to study synaptic density and integrity, making it essential for understanding synaptic function and dysfunction in various neurological conditions, including Alzheimer's disease (AD) and schizophrenia. Its expression helps in assessing synaptic health and the effects of neurodegenerative diseases on synaptic connectivity. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (459)

Biomimetic membrane-coating zinc sulfide nanoparticles for anti-inflammatory combined neuroprotective therapy for spinal cord injury.

仿生膜包覆硫化锌纳米颗粒用于脊髓损伤的抗炎联合神经保护疗法。

Qin Qin, Jin Bingrong, Bai Chaowen, Zhou Zijie, Shan Bingchen, Ding Chenhui, Han Zhihui, Wang Xi, Zhong Hao, Zhao Kai, Xie Hong, Gao Xiang, Cheng Liang, Zhou Xiaozhong

The Histone Methyltransferase KMT2D Is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration-Resistant Prostate Cancer.

组蛋白甲基转移酶 KMT2D 是去势抵抗性前列腺癌谱系可塑性和治疗反应的关键介质。

Kittane Srushti, Ladewig Erik, Li Taibo, Love Jillian R, Blawski Ryan, Gao Yangzhenyu, Arruabarrena-Aristorena Amaia, Zhao Peihua, Dalrymple Susan L, Liu Huayang, Guo Xinyu, Sallaku Mirna, Kelkar Nachiket, Garcia-Martinez Liliana, Carmona Sanz Javier, Chen Wanlu, Stoudmann Candice, Baldino Laura, Razavi-Mohseni Milad, Kalemi Ingrid, Beer Michael A, Castel Pau, Brennen W Nathaniel, Scaltriti Maurizio, Morey Lluis, Cocco Emiliano, Ji Hongkai, Chan Ho Man, Battle Alexis, Leslie Christina S, Karthaus Wouter R, Toska Eneda

Piezo1-Targeted Magnetoacoustic Nanobubbles Rescue Alzheimer's Pathology by Electromechanical Neuromodulation and Amyloid-β Clearance.

靶向压电1的磁声纳米气泡通过电机械神经调节和淀粉样蛋白β清除来挽救阿尔茨海默病病理。

Chu Fangxuan, Zhou Xiaoqing, Ma Ren, Liu Ruixu, Liu Xu, Zhu Kai, Wang Yuheng, Wang Xin, Li Ying, Zhang Shunqi, Yin Tao, Liu Zhipeng

Single-Nucleus RNA Sequencing Reveals Mid-Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate.

单核 RNA 测序揭示非综合征性唇腭裂胎儿上颞平面中期妊娠神经发育特征。

Xiong Liu-Lin, Huang Xin-Wei, Xiao Qiu-Xia, Zheng Ying-Gang, Qin Hao-Yue, Fang Chang-Le, Chen Li, Du Ruo-Lan, Wang Qiu-Lin, Huangfu Li-Ren, Fei Ye-Qing, Zhao Yang-Yang, Zhai Chen-Yang, Chen Ze-Mian, Yuan Shi-Kun, Zhou Yu-Ji, He Xing-Man, Zhi Ting-Ting, Tian Xiao-He, Wang Ting-Hua

Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient-Derived Brain Organoids.

二甲双胍可恢复 POLG 患者来源的脑类器官的线粒体功能和神经发生。

Astrocytic CCL5 orchestrates CCR5-positive neuronal necroptosis in subarachnoid hemorrhage.

星形胶质细胞 CCL5 调控蛛网膜下腔出血中 CCR5 阳性神经元的坏死性凋亡。

Downregulation of neuronal DRD2 drives microglia synaptic pruning and results in cognitive deficits by promoting CCL2 release in a rat model of chronic migraine

在慢性偏头痛大鼠模型中,神经元DRD2的下调驱动小胶质细胞突触修剪,并通过促进CCL2释放导致认知缺陷。

Yaying Yang,Xiaojian Liu,Han Wang,Haifeng Wen,Juan Zhong,Wei Zhang,Yi Xian,Yonghu Wang,Guangcheng Qin,Dunke Zhang,Lixue Chen

PTEN restrains SHH medulloblastoma growth through cell autonomous and nonautonomous mechanisms.

PTEN 通过细胞自主和非自主机制抑制 SHH 髓母细胞瘤的生长。

Lao Zhimin, El Nagar Salsabiel, Liang Yinwen, Stephen Daniel, Joyner Alexandra L

TMEM251 loss-induced autophagy dysfunction in the anterior cingulate cortex contributes to chronic postoperative pain.

TMEM251 缺失引起的前扣带皮层自噬功能障碍是导致慢性术后疼痛的原因之一。

Xu Yaowei, Xing Fei, Wei Xin, Wang Xiaoling, Shi Xiaoshan, Wang Zhongyu, Xing Na, Yuan Jingjing, Li Zhisong, Zhang Wei

Absence of Ledgf in mouse brain affects the Kmt2a/b and polycomb balance, synaptic transmission and motor function.

小鼠脑中 Ledgf 的缺失会影响 Kmt2a/b 和多梳蛋白的平衡、突触传递和运动功能。

Debusschere Laura, Bentea Eduard, Iglesias-Herrero Cecilia, Peredo Nicolas, Van Belle Siska, Van der Veken Nam Joo, Barber-Janer Anna, Plessers Dieter, Peelaerts Wouter, Hannes Wout, Michiels Martine, Van den Haute Chris, Baekelandt Veerle, Debyser Zeger
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 46