Anti-Cdk2 antibody [E304] (Ab32147)

CDKN2, CDK2, Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase

反应种属:Human, Mouse, Rat
抗原名称:CDK2
应用:WB, IHC, FCM, IF/ICC, IP

用户验证的应用

推荐稀释比例

  • IHC-P1/50 Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.
  • WB1/1000 - 1/10000
  • ICC/IF1/200 For unpurified use at 1/100.
  • Flow Cyt (Intra)1/80 ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • IP1/40

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-Cdk2 antibody [E304]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

Product Specifications Anti-Cdk2 antibody [E304] (ab32147) is a rabbit recombinant monoclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in human, mouse and rat samples. Anti-Cdk2 antibody [E304] (ab32147) specifically detects CDK2 (UniProt ID: P24941; Molecular weight: 34kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Cdk2 antibody [E304] (ab32147) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Cdk2 antibody [E304] (ab32147) has been confirmed by testing in knockout samples. Anti-Cdk2 antibody [E304] (ab32147) has been cited over 238 times in peer reviewed journals and is trusted by the scientific community. Anti-Cdk2 antibody [E304] (ab32147) has 8 independent reviews from customers. Related Products Conjugation-ready, carrier free format available for antibody clone E304 - ab208697. Antibody clone E304 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 555, PE, APC, HRP, Alkaline Phosphatase, Alexa Fluor® 488, Alexa Fluor® 568, Alexa Fluor® 750 ( ab206038, ab207858, ab208043, ab305638, ab305639, ab305640, ab308701, ab309676, ab312419, ab321583 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (236)

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Zhang Han, Zhang Li, Feng Zehao, Li Xing, Qiu Zhaohui, Wang Xingyun, Qian Lingmei

CDK2 inhibition promotes neuronal differentiation in neuroblastoma.

CDK2抑制促进神经母细胞瘤中的神经元分化。

Alzrigat Mohammad, Mahmoud Loay, Topçu Ada Nursel, Valenti Marta, Zhang Lu, Veen Puck, John Fabian, Bazzar Wesam, Lehti Kaisa, Larsson Lars-Gunnar

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lncRNA Gm44981通过调控EZH2-H3K27me3-p21轴抑制系膜细胞衰老和肾脏老化

Jie Li,Limin Wei,Fanfan Gao,Lu Zeng,Hongli Jiang,Lei Chen

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

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Shiekh Tanveer Ahmad ,Yiran Li ,Jesus Garcia-Lopez ,Brian L Gudenas ,Jennifer Hadley ,Leena Paul ,Stephanie C Wu ,Alaa Refaat ,Marija Kojic ,Melissa Batts ,Taha Soliman ,Aaron Pitre ,Frederik Arnskötter ,Frederique Zindy ,Alun Jones ,Nathaniel R Twarog ,Anand Mayasundari ,Brandon Bianski ,Christopher Tinkle ,Abbas Shirinifard ,Laura Janke ,Meifen Lu ,Sara A Lewis ,Arzu Onar-Thomas ,Stefan M Pfister ,Amar Gajjar ,Suzanne J Baker ,Martine F Roussel ,Zoran Rankovic ,Giles W Robinson ,Brent A Orr ,Brandon Wainwright ,Anang A Shelat ,Sebastian M Waszak ,Lena M Kutscher ,Hong Lin ,Paul A Northcott

Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer

环状 RNA circBNC2 通过调节铁死亡来抑制肿瘤发生,并作为前列腺癌的纳米治疗靶点

Xiang Pan #, Kailai Chen #, Wei Gao #, Meiqi Xu, Fanlong Meng, Mengyuan Wu, Zi Qi Wang, Yun Qi Li, Wanhai Xu, Manjie Zhang, Yakun Luo

TRAF7 knockdown induces cellular senescence and synergizes with lomustine to inhibit glioma progression and recurrence.

TRAF7 敲低可诱导细胞衰老,并与洛莫司汀协同抑制胶质瘤的进展和复发

Chen Yu, Zhou Tongyu, Zhou Rongrong, Sun Wen, Li Yan, Zhou Qiyi, Xu Dongcheng, Zhao Yuxin, Hu Peihao, Liang Jingrui, Zhang Yumeng, Zhong Bin, Yao Juncheng, Jing Di

Targeted inhibition of Ninjurin2 promotes chemosensitivity in chemoresistant gastric cancer by suppressing cancer-initiating cells.

靶向抑制 Ninjurin2 可抑制癌细胞起始细胞,从而提高耐药性胃癌的化疗敏感性

Shin Hyo Shik, Choi Jae-Il, Chung Hye Won, Park Hee Jung, Park Hak, Rim John Hoon, Lim Jong-Baeck

Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization.

Speedy A 控制非同源 XY 染色体解联会,这是 XY 环轴组织的独特先决条件

Liu Dongteng, Zhang Yuxiang, Li Dongliang, Jiang Binjie, Zhao Xudong, Li Yanyan, Lin Zexiong, Zhao Yu, Hu Zhe, Deng Shuzi, Li Zheng, Lu Haonan, Chan Karen K L, Yeung William S B, Kaldis Philipp, Yao Chencheng, Wang Hengbin, Chow Louise T, Liu Kui

ARRB2 promotes cervical cancer progression via stabilizing CDC25A mRNA through m6A-IGF2BP1-dependent manner.

ARRB2 通过 m6A-IGF2BP1 依赖的方式稳定 CDC25A mRNA,从而促进宫颈癌的进展

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干扰素调节因子 4 介导多发性骨髓瘤细胞中非酶促 IRE1 依赖性

Oikonomidi Ioanna, Kameswaran Vasumathi, Pham Victoria C, Zuazo-Gaztelu Iratxe, Gutgesell Lauren M, Marsters Scot, Daniel Bence, Lill Jennie R, Modrusan Zora, Ashkenazi Avi
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