Anti-Collagen II antibody (Ab34712)
Collagen alpha-1(II) chain, Alpha-1 type II collagen, COL2A1
详细信息
特异性
Some class specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues. This antibody reacts with most mammalian Type II collagens and has expected cross-reactivity with Type IV and VI and negligible cross reactivity to Type I, III and V collagens. Non-specific cross reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins has not been tested.
背景信息
Anti-Collagen II antibody (ab34712) is a rabbit polyclonal antibody and is validated for use in IHC-P and Dot Blot. Anti-Collagen II antibody (ab34712) was first used in a scientific publication in 2008 and has been cited over 766 times in peer reviewed journals. It's performance in Western blot and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Collagen II antibody (ab34712) has high sensitivity and specificity. Anti-Collagen II antibody (ab34712) has 16 independent reviews from customers. Anti-Collagen II antibody (ab34712) specifically detects Collagen II (UniProt ID: P02458; Molecular weight: 97kDa) and is sold in 100 ug selling sizes. Top cited antibody for this target with >900 citations. Highly-validated collagen type II antibody, essential for researchers studying joint health and cartilage support. This antibody is crucial in osteoarthritis treatment research, particularly in understanding collagen II's benefits and sources. It is widely used in studies of collagen II supplements and ongoing collagen II research.
文献引用 (941)
From disease model to therapeutic insight: An engineered hydrogel reveals the role of matrix viscous dissipation in intervertebral disc degeneration.
从疾病模型到治疗见解:工程水凝胶揭示了基质粘性耗散在椎间盘退变中的作用。
Injectable microgels loaded with programmable WELNs based on mendelian randomization macroanalysis alleviate osteoarthritis by restoring the circadian rhythm.
基于孟德尔随机化宏观分析的、载有可编程 WELN 的可注射微凝胶,通过恢复昼夜节律来缓解骨关节炎。
Osteoclast-Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes.
破骨细胞衍生的 SLIT3 介导骨关节炎疼痛和退行性改变。
Targeted Inhibition of CD74(+) Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression.
木犀草素通过 CEBPB/P65 信号通路靶向抑制 CD74(+) 巨噬细胞,从而改善骨关节炎的进展。
α-Ketoglutarate protects against cartilage damage via epigenetically driven metabolic reprogramming in osteoarthritis models.
α-酮戊二酸通过表观遗传驱动的代谢重编程在骨关节炎模型中保护软骨免受损伤。
Piezoelectric scaffold with enhanced effect drives the healing of osteochondral defects through electromechanical-immune coupling.
具有增强效果的压电支架通过电机械免疫耦合促进骨软骨缺损的愈合。
Mannose Oligosaccharide-Conjugated In Situ Pore-Forming Injectable Hydrogels for Rheumatoid Arthritis Treatment by Reprogramming Macrophage Extracellular Vesicles
通过重编程巨噬细胞外囊泡,制备用于治疗类风湿性关节炎的甘露糖寡糖偶联原位成孔注射水凝胶
Exploring Injectable Scaffolded Spheroids for Nucleus Pulposus Therapy in Degenerated Intervertebral Discs.
探索可注射支架球体在退变椎间盘髓核治疗中的应用。
The 3D printed biphasic scaffolds incorporating epimedin C promotes osteochondral regeneration in osteoarthritis rats.
含有表皮素 C 的 3D 打印双相支架可促进骨关节炎大鼠的骨软骨再生。
Therapeutic efficacy of extracellular vesicles from hiPSC-derived MSCs in serum-containing and xeno-free media for osteoarthritis treatment.
hiPSC衍生的MSC细胞外囊泡在含血清和无异种成分培养基中治疗骨关节炎的疗效。
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