详细信息
特异性
Specifically binds to HNE modified proteins.
背景信息
Anti-4 Hydroxynonenal antibody (ab46545) is a rabbit polyclonal antibody and is validated for use in WB. Anti-4 Hydroxynonenal antibody (ab46545) was first used in a scientific publication in 2008 and has been cited over 658 times in peer reviewed journals. It's performance in Western blot is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-4 Hydroxynonenal antibody (ab46545) has high sensitivity and specificity. Anti-4 Hydroxynonenal antibody (ab46545) has 25 independent reviews from customers. Anti-4 Hydroxynonenal antibody (ab46545) specifically detects 4 Hydroxynonenal (UniProt ID: N/A; Molecular weight: 0.1kDa) and is sold in 100 ug selling sizes. 4-Hydroxynonenal is essential for detecting oxidative stress markers in cells, aiding research on diseases related to oxidative damage.
文献引用 (843)
A mast cell receptor mediates post-stroke brain inflammation via a dural-brain axis
肥大细胞受体通过硬脑膜-脑轴介导卒中后脑炎症。
Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance.
放射疗法可促进铜细胞凋亡，并与铜细胞凋亡诱导剂协同作用，克服肿瘤放射抗性
Self-amplifying NRF2-EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer.
自我扩增的 NRF2-EZH2 表观遗传环将 KRAS 启动的祖细胞转化为侵袭性胰腺癌
Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity
镰状细胞病诱导CD8+ T细胞染色质内翻和铁死亡，从而抑制抗肿瘤免疫。
Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer.
精氨酸缺乏可诱导结直肠癌细胞静止并使其易受铁死亡的影响
Ubiquinol-mediated suppression of mitochondria-associated ferroptosis is a targetable function of lactate dehydrogenase B in cancer.
泛醌介导的线粒体相关铁死亡抑制是乳酸脱氢酶 B 在癌症治疗中的一种可靶向功能
DHODH modulates immune evasion of cancer cells via CDP-Choline dependent regulation of phospholipid metabolism and ferroptosis.
DHODH 通过 CDP-胆碱依赖性调节磷脂代谢和铁死亡来调节癌细胞的免疫逃逸
AKAP1/PKA-mediated GRP75 phosphorylation at mitochondria-associated endoplasmic reticulum membranes protects cancer cells against ferroptosis.
AKAP1/PKA介导的GRP75在与线粒体相关的内质网膜上的磷酸化可保护癌细胞免受铁死亡的影响
Targeting ALDH16A1 mediated thioredoxin lysosomal degradation to enhance ferroptosis susceptibility in SMARCA4-deficient NSCLC
靶向ALDH16A1介导的硫氧还蛋白溶酶体降解以增强SMARCA4缺陷型非小细胞肺癌的铁死亡敏感性
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