Anti-Smad3 antibody [EP568Y] (Ab40854)

MADH3, SMAD3, SMAD family member 3, SMAD 3, hSMAD3, JV15-2, Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3

反应种属:Human, Rat
抗原名称:SMAD3
应用:WB, ELISA, FCM, IF/ICC, CUT&RUN-seq

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

What is this antibody validated in? Anti-Smad3 antibody [EP568Y] (ab40854) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Human, Rat samples. What is the molecular weight of Smad3? Anti-Smad3 [EP568Y] (ab40854) specifically detects a band for Smad3 (UniProt: P84022) at a molecular weight of 48kDa. Trusted by the scientific community Anti-Smad3 [EP568Y] (ab40854) was first used in a scientific publication in 2006 and has been cited over 300 times in peer-reviewed journals. Reviewed by scientists Anti-Smad3 [EP568Y] (ab40854) has over 10 independent reviews from customers. Specificity confirmed The specificity of Anti-Smad3 antibody [EP568Y] (ab40854) has been confirmed by Western blot testing in SMAD3 Knockout A549 cells. Other related products We have a range of other formats of antibody clone [EP568Y] also available for your convenience: ab40854, Carrier free - ab157372, Alexa Fluor ® 488 - ab204257, Alexa Fluor ® 647 - ab204461, HRP - ab204462, Alexa Fluor ® 594 - ab206350, Alexa Fluor ® 555 - ab206582, PE - ab208751 Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (321)

Bioengineered exosome-mRNA hybrids: a breakthrough in targeted miRNA delivery for diabetic kidney fibrosis therapy.

生物工程外泌体-mRNA杂交体:糖尿病肾纤维化治疗中靶向miRNA递送的突破。

Ke Jing, Cao Lei, Zhang Shaochun, Xing Jili

Elevated circulating GDF11 and its role in age-related sarcopenia: insights from clinical, transcriptomic, and in vitro analyses.

循环中 GDF11 水平升高及其在年龄相关性肌肉减少症中的作用:来自临床、转录组学和体外分析的见解。

Chen Rui, Dai Xin, Wang Hong, Zhang Ting, Zhang Zhao, Liu Yaoxia, Fan Zhen

Yixiao Formula Suppresses Myocardial Fibrosis Through UpregulatingmiR-133a and Downregulating TGF-β/Smads Signal Molecules.

益逍方通过上调 miR-133a 和下调 TGF-β/Smads 信号分子抑制心肌纤维化。

Zhao Qiyao, Wen Yalu, Wu Honghui, Li Jiaoyue, Luo Yunpeng, Li Ping, Zhang Ye, Hu Chaoyue, Huang Jukai, Zhang Li, Yang Xiaohui

PTTG1 regulates the TGF-β/Smad pathway to promote the growth and metastasis of gastric cancer cells.

PTTG1 调节 TGF-β/Smad 通路,促进胃癌细胞的生长和转移。

Wang Dong, Geng Hui, Xia Ziwei, Qiu Chenjie

Mechanical confinement governs phenotypic plasticity in melanoma

机械限制调控黑色素瘤的表型可塑性

Miranda V Hunter,Eshita Joshi,Sydney Bowker,Emily Montal,Yilun Ma,Young Hun Kim,Zhifan Yang,Laura Tuffery,Zhuoning Li,Eric Rosiek,Alexander Browning,Reuben Moncada,Itai Yanai,Helen Byrne,Mara Monetti,Elisa de Stanchina,Pierre-Jacques Hamard,Richard P Koche,Richard M White

Blockade of αvβ6 and αvβ8 integrins with a chromogranin A-derived peptide inhibits TGFβ activation in tumors and suppresses tumor growth

使用嗜铬粒蛋白 A 衍生肽阻断 αvβ6 和 αvβ8 整合素可抑制肿瘤中的 TGFβ 活化并抑制肿瘤生长

Anna Maria Gasparri #, Arianna Pocaterra #, Barbara Colombo, Giulia Taiè, Chiara Gnasso, Alessandro Gori, Federica Pozzi, Andrew Smith, Fulvio Magni, Alessia Ugolini, Matteo Doglio, Maria Chiara Bonini, Anna Mondino, Angelo Corti, Flavio Curnis0

TGF-β1/SMAD3-mediated Non-canonical Hedgehog Signaling Promotes Pancreatic Stellate Cell Activation and Fibrosis in Chronic Pancreatitis.

TGF-β1/SMAD3介导的非经典Hedgehog信号通路促进慢性胰腺炎中胰腺星状细胞活化和纤维化。

Peng Linrui, Hu Yuchen, Zhang Xiaoying, Tan Chunlu, Yang Chan, Liu Tingting, Ferdek Pawel E, Yin Shufen, Wang Liu, Huang Wei, Zhang Yuwei

Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.

靶向 SMAD3/CISD2 轴可促进间质样膀胱癌细胞发生铁死亡,从而抑制膀胱癌的进展。

Sun Yulin, Wang Jianghui, Gu Da, Lou Huanmin, Sun Jinpeng, Cui Zilian, Kang Weiting

Cellular senescence promotes macrophage-to-myofibroblast transition in chronic ischemic renal disease.

细胞衰老促进慢性缺血性肾病中巨噬细胞向肌成纤维细胞的转化

Zhao Yu, Zhu Xiang-Yang, Ma Wenqi, Zhang Ying, Yuan Fei, Kim Seo Rin, Tang Hui, Jordan Kyra, Lerman Amir, Tchkonia Tamara, Kirkland James L, Lerman Lilach O

Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.

纤维生成驱动的透明细胞肾细胞癌肿瘤进展:预后、治疗意义以及神经纤毛蛋白-1的双重作用

Wang Kai, Shen Xihao, Wu Jiyue, Bi Qing, Gao Zihao, Sun Zejia, Wang Wei
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