Anti-LC3B antibody - Autophagosome Marker (Ab48394)
MAP1ALC3, MAP1LC3B, Microtubule-associated protein 1 light chain 3 beta, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, Microtubule-associated proteins 1A/1B light chain 3B, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B
详细信息
背景信息
Anti-LC3B antibody - Autophagosome Marker (ab48394) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P, WB in human samples. Anti-LC3B antibody - Autophagosome Marker (ab48394) has been cited over 701 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-LC3B antibody - Autophagosome Marker (ab48394) has high sensitivity and specificity. Anti-LC3B antibody - Autophagosome Marker (anti-MAP1LC3B antibody) (ab48394) has 32 independent reviews from customers. Anti-LC3B antibody - Autophagosome Marker (ab48394) specifically detects LC3B (UniProt ID: Q9GZQ8; Molecular weight: 14kDa) and is sold in 100 µL selling sizes. LC3B (MAP1LC3B) or Microtubule-associated protein 1 light chain 3 beta is a key marker of autophagy, a process that cancer cells often exploit for survival and growth. Elevated LC3B expression is commonly observed in various solid tumors and is associated with increased tumor proliferation and metastasis. LC3B facilitates the formation of autophagosomes, which help cancer cells manage stress and maintain cellular homeostasis.
文献引用 (761)
Mycobacterial α-glucans hijack dectin-1 to facilitate intracellular bacterial survival
分枝杆菌α-葡聚糖劫持dectin-1以促进细菌在细胞内存活
VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement.
VAMP7 依赖的内质网和线粒体蛋白的晚期内体分泌会影响肿瘤微环境和巨噬细胞的参与。
NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development.
黑素细胞中 NLRP3 自噬降解紊乱是导致白癜风发生的原因之一。
mTOR-driven autophagy suppression defines metabolic vulnerability in CDK4/6 inhibitor-resistant HR(+)/HER2(-) breast cancer.
mTOR 驱动的自噬抑制定义了 CDK4/6 抑制剂耐药的 HR(+)/HER2(-) 乳腺癌的代谢脆弱性。
The amino acid transporter LAT1 coordinates proper motor function at the perinatal stage.
氨基酸转运蛋白 LAT1 在围产期协调正常的运动功能。
Recombinant tissue plasminogen activator protects neurons after intracerebral hemorrhage through activating the PI3K/AKT/mTOR pathway.
重组组织型纤溶酶原激活剂通过激活 PI3K/AKT/mTOR 通路来保护脑出血后的神经元
Fibroblast growth factor-inducible 14 accelerates pulmonary fibrosis by inducing fibroblast senescence in mice.
成纤维细胞生长因子诱导因子 14 通过诱导小鼠成纤维细胞衰老来加速肺纤维化。
Vinorelbine enhances the efficacy of oncolytic vaccinia virus in a preclinical model of ovarian high-grade serous carcinoma.
长春瑞滨可增强溶瘤痘苗病毒在卵巢高级别浆液性癌临床前模型中的疗效。
Microtubule affinity-regulating kinase 4 exacerbates diabetic cardiomyopathy by inhibiting UNC-51-like kinase 1-mediated mitochondrial autophagy.
微管亲和力调节激酶 4 通过抑制 UNC-51 样激酶 1 介导的线粒体自噬来加剧糖尿病心肌病。
Effects of leonurine supplementation during in vitro culture on oxidative stress, cell proliferation, apoptosis, and autophagy in bovine embryos.
益母草碱补充剂在体外培养过程中对牛胚胎氧化应激、细胞增殖、细胞凋亡和自噬的影响。
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