Anti-SREBP1 antibody [2A4] (Ab3259)

BHLHD1, SREBP1, SREBF1, Sterol regulatory element-binding protein 1, SREBP-1, Class D basic helix-loop-helix protein 1, Sterol regulatory element-binding transcription factor 1, bHLHd1

反应种属:Human
抗原名称:SREBF1
应用:WB

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification
储存缓冲液Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com

文献引用 (104)

GCN5 drives MASLD progression through LXRα/SREBP1c signaling pathway-mediated de novo lipogenesis.

GCN5 通过 LXRα/SREBP1c 信号通路介导的从头脂肪生成驱动 MASLD 进展。

Xiao Hai-Tao, Song Peng, Jin Jing, Wang Yong-Dan, Xu Yin-Yue, Wu He, Shao Xue-Xue, Gan Qi-Feng, He Jian, Wen Yan-Rong, Zhu Jing, Chen Bao-Yi, Zhou Ping, Lai Li-Na, Yang Hua, Li Ping, Zheng Zu-Guo

Targeting fatty acid metabolism in hepatic macrophages mitigates acetaminophen-induced liver injury and promotes regeneration in mice.

靶向肝脏巨噬细胞中的脂肪酸代谢可减轻对乙酰氨基酚引起的小鼠肝损伤并促进肝再生。

The ionotropic AMPA receptor contributes to autoimmunity via altered regulatory T cell differentiation.

离子型 AMPA 受体通过改变调节性 T 细胞分化而导致自身免疫性疾病。

Mitchell-Flack Marisa, Higgins Makenzie, Zheng Ying, Tam Ada, Goldschmidt Hana, Nishio Hiroshi, Liu Bian, Cherry Christopher M, Patatanian Michael, Blosser Richard, Mun Sung Soo, Suru Aditya, Huganir Richard, Yu Hong, Pardoll Drew

Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism

FLAD1 拷贝数扩增通过脂质代谢促进三阴性乳腺癌进展

Xiao-Qing Song #, Tian-Jian Yu #, Yang Ou-Yang #, Jia-Han Ding, Yi-Zhou Jiang, Zhi-Ming Shao, Yi Xiao

Maternal fish oil supplementation enhances nutrient transport in the placenta and milk biosynthesis in the mammary gland via the GPR120 signaling pathway.

母体补充鱼油可通过 GPR120 信号通路增强胎盘中的营养物质运输和乳腺中的乳汁生物合成。

Li Qihui, Zhang Qianzi, Su Senlin, Yang Siwang, Shao Jiayuan, Guan Wutai, Zhang Shihai

PERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape.

内质网和非中心体微管之间 PERK 依赖的相互串扰协调内质网结构和细胞形状。

Sánchez-Álvarez Miguel, Lolo Fidel Nicolás, Sailem Heba, Fulgoni Giulio, Pascual-Vargas Patricia, Agüera Lucía, Catalá-Montoro Mauro, Arias-García Mar, López Juan Antonio, Vázquez Jesús, Del Pozo Miguel Ángel, Bakal Chris

Biomarker-Driven Optimization of Saponin Therapy in MASLD: From Mouse Models to Human Liver Organoids.

基于生物标志物的皂苷疗法在MASLD中的优化:从小鼠模型到人类肝脏类器官

Kim Hye Young, Oh Ju Hee, Kim Hyun Sung, Jun Dae Won

Lipolysis-derived fatty acids are needed for homeostatic control of sterol element-binding protein-1c driven hepatic lipogenesis

脂肪分解产生的脂肪酸对于维持甾醇元素结合蛋白-1c驱动的肝脏脂肪生成的稳态控制至关重要。

Paola Peña de la Sancha # ,Beatrix Irene Wieser # ,Silvia Schauer ,Helga Reicher ,Wolfgang Sattler ,Rolf Breinbauer ,Martina Schweiger ,Margarete Lechleitner ,Saša Frank ,Rudolf Zechner ,Dagmar Kratky ,Peter John Espenshade ,Gerald Hoefler ,Paul Willibald Vesely

Maresin 1 Ameliorates Blue Light Overexposure-Induced Meibomian Gland Dysfunction via Inhibition of NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis.

Maresin 1 通过抑制 NLRP3/Caspase-1/GSDMD 介导的细胞焦亡来改善蓝光过度暴露引起的睑板腺功能障碍。

Wu Meng, He Hao-Lan, Wang Chao, Wang Bei, Li Yu-Zhi, Zhou Shi-Rui, Cai Wan-Ying, Xiong Ni, Zhang Ming-Chang, Xie Hua-Tao

Liver specific transgenic expression of CYP7B1 attenuates early western diet-induced MASLD progression.

肝脏特异性转基因表达CYP7B1可减轻早期西方饮食诱发的MASLD进展

Kakiyama Genta, Bai-Kamara Nanah, Rodriguez-Agudo Daniel, Takei Hajime, Minowa Kei, Fuchs Michael, Biddinger Sudha, Windle Jolene J, Subler Mark A, Murai Tsuyoshi, Suzuki Mitsuyoshi, Nittono Hiroshi, Sanyal Arun, Pandak William M
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