Anti-Histone H3 (di methyl K79) antibody - ChIP Grade (AB3594)

H3FA, HIST1H3A, H3C2, H3FL, HIST1H3B, H3C3, H3FC HIST1H3C, H3C4, H3FB, HIST1H3D, H3C6, H3FD, HIST1H3E, H3C7, H3FI, HIST1H3F, H3C8, H3FH, HIST1H3G, H3C10, H3FK, HIST1H3H, H3C11, H3FF, HIST1H3I, H3C12, H3FJ, HIST1H3J, H3FC, HIST1H3C, H3C1, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, H3K79me2, H3K79me, H3K79

反应种属:Human, Mouse, Bovine
抗原名称:H3C1 di methyl K79
应用:WB, IHC, IF/ICC, ChIP, Peptide Array

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Immunogen
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

ab3594 detects a 17 kDa band in single lane Western Blot. Peptide inhibition in Western Blot hasn't been processed. Modification specificity is determined by Peptide Array. ab3594 binds strongly to the Histone H3 dii methyl K79. In Peptide Array ab3594 also partially binds to mono methyl K79 and tri methyl K79 peptides.

背景信息

What is this antibody validated in? Anti-Histone H3 (di methyl K79) antibody - ChIP Grade (ab3594) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP, Peptide Array in Cow, Human, Mouse samples. What is the molecular weight of Histone H3? Anti-Histone H3 (di methyl K79) - ChIP Grade (ab3594) specifically detects a band for Histone H3 (UniProt: P68431) at a molecular weight of 15kDa. Trusted by the scientific community Anti-Histone H3 (di methyl K79) - ChIP Grade (ab3594) was first used in a scientific publication in 2003 and has been cited over 230 times in peer-reviewed journals. Reviewed by scientists Anti-Histone H3 (di methyl K79) - ChIP Grade (ab3594) has over 15 independent reviews from customers.

文献引用 (287)

Trans-histone crosstalk establishes distinct H3K79 methylation zones with differential transcriptional functions.

组蛋白间的相互作用建立了具有不同转录功能的不同 H3K79 甲基化区域。

Park Na Hyun, Kim Hwa-Ryeon, Kim Hye Young, Lee Soo Young, Cho Yong-Joon, Roe Jae-Seok, Kim TaeSoo

Aβ antibodies target not only amyloid plaques but also distinct brain cells and vessels.

Aβ抗体不仅靶向淀粉样斑块,还靶向特定的脑细胞和血管。

Wen Gehua, Lindblom Nils, Zhan Xiaoni, Garcia-Ryde Megg, Deierborg Tomas, Kobro-Flatmoen Asgeir, Gouras Gunnar K

IGF2BP3 recognizes m6A to regulate histone-to-protamine replacement during mouse sperm development

IGF2BP3识别m6A,从而调节小鼠精子发育过程中组蛋白向鱼精蛋白的替换

Dazhuang Wang #,Zhenyi Huang #,Yichun Zhou #,Peiyan Chen #,Gang Chang #,Liwei Ke,Congying Jing,Haojie Yang,Jiexiang Zhao,Shaofang Ren,Yi Zheng,Yuhan Chen,Yunfan Xiang,Jun Liu,Mei Wang

RBM15B recognizes H3K79me2 to guide selective m(6)A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia.

RBM15B 识别 H3K79me2 以指导 mRNA 的选择性 m(6)A 修饰,并增强 MLL-r 白血病中的癌蛋白翻译。

Single-cell transcriptomic analyses reveal angiogenic vascular responses to chronic cerebral hypoperfusion.

单细胞转录组分析揭示了慢性脑低灌注引起的血管生成反应。

Shan Jiajing, Shi Ruyu, Jiang Liyuan, Dufort Connor, Miao Wanying, Mai Ting-Wei, Lyu Junxuan, Barreiro Julieta, Chen Kong, Leak Rehana K, Chen Jun, Hu Xiaoming

Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling.

人类内皮细胞通过 Notch 信号通路促进人类神经干细胞 B 型表型的形成

Gutierrez Brenda, Liu Tzu Chia, Rodriguez Carly, Pastor-Alonso Oier, Lambing Hannah, Paredes Mercedes F, Flanagan Lisa A

Molecular profiling of brain endothelial cell to astrocyte endfoot communication in mouse and human

小鼠和人类脑内皮细胞与星形胶质细胞终足通讯的分子谱分析

Steven A Hill # ,Isabel Bravo-Ferrer # ,Austėja Čiulkinytė ,Noelia Pérez Ramos ,Ilaria Rossetti ,Chiara Colvin ,Paula Beltran-Lobo ,Carlos Parra-Pérez ,Katie Emelianova ,Owen Dando ,Beth Geary ,Raja S Nirujogi ,Dario R Alessi ,Do-Young Lee ,Youn-Bok Lee ,Blanca Díaz Castro

Regionally mapped astrocytic responses to cortical and white matter stroke show differential roles in astrocyte-induced vascular remodeling

区域性星形胶质细胞对皮质和白质卒中的反应显示出在星形胶质细胞诱导的血管重塑中不同的作用

Amy J Gleichman ,Riki Kawaguchi ,Elle M Rathbun ,Michael V Sofroniew ,S Thomas Carmichael

Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer's disease

视觉回路激活对脑淋巴系统的调节可缓解阿尔茨海默病小鼠模型的记忆障碍和冷漠症状

Wen Wu # ,Yubai Zhao # ,Xin Cheng # ,Xiaoru Xie ,Yixiu Zeng ,Quan Tao ,Yishuai Yang ,Chuan Xiao ,Zhan Zhang ,Jiahui Pang ,Jian Jin ,Hongbo He ,Yangyang Lin ,Boxing Li ,Junxian Ma ,Xiaojing Ye ,Wei-Jye Lin

Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39

小胶质细胞通过胞外核苷酸酶CD39调节脑血管反应性

Zhongxiao Fu ,Mallikarjunarao Ganesana ,Philip Hwang ,Xiao Tan ,Melissa Marie Kinkaid ,Yu-Yo Sun ,Emily Bian ,Aden Weybright ,Hong-Ru Chen ,Katia Sol-Church ,Ukpong B Eyo ,Clare Pridans ,Francisco J Quintana ,Simon C Robson ,Pankaj Kumar ,B Jill Venton ,Anne Schaefer ,Chia-Yi Kuan
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