Anti-CD68 antibody [FA-11] (Ab53444)

Anti-CD68 antibody [FA-11] (ab53444) is a rat recombinant monoclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF in dog, human, mouse, rat samples. Anti-CD68 antibody [FA-11] (ab53444) has been cited over 312 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-CD68 antibody [FA-11] (ab53444) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD68 antibody [FA-11] (ab53444) has 24 independent reviews from customers. Anti-CD68 antibody [FA-11] (Anti-Macrosialin antibody) (ab53444) specifically detects CD68 (UniProt ID: P34810; Molecular weight: 35kDa) and is sold in 100 µg and 1 mg selling sizes. Conjugation-ready, carrier free format available for antibody clone FA-11 - ab237968. Antibody clone FA-11 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 405, Alexa Fluor® 488, Alexa Fluor® 647, HRP, PE, PerCP, APC ( ab199571, ab201844, ab201845, ab216526, ab216701, ab220509, ab221251 ). CD68 is a transmembrane glycoprotein predominantly expressed on macrophages, playing a crucial role in the immune system. It is involved in phagocytosis and antigen presentation, making it essential for immune responses. CD68 is expressed in various macrophage subtypes, including M1 (pro-inflammatory) and M2 (anti-inflammatory), contributing to both inflammation and tissue repair. In the central nervous system, CD68 is a marker for microglia, the brain's immune cells, and is involved in clearing cellular debris and modulating inflammatory responses. Its expression levels can influence the progression of neurodegenerative diseases and other immunological conditions. Although some customers have had success with this antibody in IHC-P, we are unable to obtain positive results in this application and so cannot recommend it for IHC-P. We batch test the antibody in IHC-Fr. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.