Anti-GFAP antibody - Astrocyte Marker (Ab53554)
Glial fibrillary acidic protein, GFAP
详细信息
背景信息
Find all reagents to label astrocytes in our " Astrocytes markers guide ". Anti-GFAP antibody (ab53554) is a Goat Polyclonal antibody and is validated for use in WB in cow, human, mouse, rat samples. Anti-GFAP antibody (ab53554) has been cited over 392 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-GFAP antibody (ab53554) has high sensitivity and specificity. Anti-GFAP antibody (ab53554) has 24 independent reviews from customers. Anti-GFAP antibody (ab53554) specifically detects GFAP (UniProt ID: P14136; Molecular weight: 50kDa) and is sold in 100 ug selling sizes. GFAP (Glial Fibrillary Acidic Protein) is a key marker in neuro research, particularly for its role in identifying astrocyte activity. It is predominantly expressed in astrocytes, the most abundant glial cells in the brain and spinal cord. Altered GFAP levels are associated with various neurological conditions, including Alzheimer's disease (AD), traumatic brain injury (TBI), and multiple sclerosis (MS). Researchers use GFAP to assess astrocytic response and neuroinflammation, making it essential for understanding the extent of brain injury and the progression of neurodegenerative diseases.
文献引用 (533)
Thermally Drawn Multifunctional All-Hydrogel Fibers for Anti-Fibrotic and Multimodal Neural Interfaces.
用于抗纤维化和多模态神经接口的热拉伸多功能全水凝胶纤维。
Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition.
针对老年大脑中的免疫细胞的研究表明，工程细胞因子 IL-10 可以增强神经发生并改善认知能力。
A novel lncRNA, lncMCL1, modulates neural pyroptosis associated with epilepsy via stabilizing DDX3X.
一种新型 lncRNA，lncMCL1，通过稳定 DDX3X 来调节与癫痫相关的神经元焦亡。
Astrocytic glucose metabolism regulates the survival of newborn hippocampal neurons in the adult brain.
星形胶质细胞的葡萄糖代谢调节成年大脑中新生海马神经元的存活。
Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug-Releasing Capability for the Programmable Repair of Spinal Cord Injury.
具有顺序药物释放能力的纳米凝胶集成两性离子可注射水凝胶，用于可编程修复脊髓损伤。
Piezo1 induces Wnt7b+ astrocytes transformation to modulate glial scar stiffness and neuro-regeneration after stroke
Piezo1诱导Wnt7b+星形胶质细胞转化，从而调节卒中后胶质瘢痕的硬度和神经再生。
Macrophage-glia interactions regulate immune damage to enteric neurons during West Nile virus infection.
巨噬细胞与神经胶质细胞的相互作用调节西尼罗病毒感染期间对肠神经元的免疫损伤。
De-2-hydroxyisobutyrylation of clusterin modulates neuropathology and memory deficits in an Alzheimer's disease mouse model.
簇蛋白的去-2-羟基异丁酰化作用调节阿尔茨海默病小鼠模型中的神经病理学和记忆缺陷。
Modeling spastic paraplegia 4 with corticospinal motor neuron-enriched cortical organoids reveals genotype-phenotype and HDAC6-targetable pathology.
利用富含皮质脊髓运动神经元的皮质类器官对痉挛性截瘫 4 进行建模，揭示了基因型-表型和 HDAC6 可靶向的病理。
ADAMTS-7 Increase Contributes to Worsened Neurological Outcome in Mice on High Fat Diet.
ADAMTS-7 增加导致高脂饮食小鼠神经系统预后恶化。
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