Anti-Beclin 1 antibody (Ab62557)

GT197, BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197

反应种属:Human, Mouse, Rat
抗原名称:BECN1
应用:WB, IHC, IF/ICC, IF

详细信息

免疫原Synthetic Peptide within Human BECN1. The exact immunogen used to generate this antibody is proprietary information. Q14457
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Immunogen
储存缓冲液pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
储存条件运输条件: Blue Ice 推荐的短期储存条件: +4°C 推荐的长期储存条件: +4°C
无载体蛋白No

背景信息

What is this antibody validated in? Anti-Beclin 1 antibody (ab62557) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Beclin 1? Anti-Beclin 1 (ab62557) specifically detects a band for Beclin 1 (UniProt: Q14457) at a molecular weight of 52kDa. Trusted by the scientific community Anti-Beclin 1 (ab62557) was first used in a scientific publication in 2008 and has been cited over 290 times in peer-reviewed journals. Reviewed by scientists Anti-Beclin 1 (ab62557) has over 5 independent reviews from customers.

文献引用 (287)

In the diffuse large B-cell lymphoma microenvironment, SIRT1 is upregulated and correlated with a pro-inflammatory macrophage signature and autophagy-related gene expression.

在弥漫性大B细胞淋巴瘤微环境中,SIRT1 上调,并与促炎巨噬细胞特征和自噬相关基因表达相关。

Resanoa Miguel, Azcoaga Peio, Salvador Naike, Delgado Alba, Rodiño Claudia, Schoenhals Matthieu, Braza Mounia S

Hydrogen-rich water alleviates neuropathic pain through the modulation of bile acid/Takeda G-protein-coupled receptor 5-mediated autophagy.

富氢水通过调节胆汁酸/Takeda G 蛋白偶联受体 5 介导的自噬来缓解神经性疼痛。

Zeng Xuejiao, Lin Jiaqi, Liu Botao, Su Zehua, Yu Yongze, Li Xin, Duan Wenying, Liu Chunzheng, Hou Qianhao, Zhang Jinyuan, Yang Longqiu, Liu Xiaodong, Fan Bifa, Liao Lijun

Hsa_circ_0101645 contributes to excessive autophagy and apoptosis in intervertebral disc degeneration by acting as a miR-1304-5p sponge modulating BNIP3 expression.

Hsa_circ_0101645 通过作为 miR-1304-5p 海绵调节 BNIP3 表达,促进椎间盘退变中的过度自噬和细胞凋亡。

Luo Jianhai, Yu Tong, Hu Pengcheng, Liu Jie

Formyl Peptide Receptor-2-Suppressed Autophagy Promotes the Migration and Invasion of Human Glioblastoma Cells Through PI3K/Akt Signaling.

甲酰肽受体-2抑制自噬通过PI3K/Akt信号通路促进人类胶质母细胞瘤细胞的迁移和侵袭。

Luo Zhenzhao, Kong Deyong, Qi Guangjian, Zheng Chao, Zhao Wushi, Lu Zhongxin

Epidermal growth factor receptor regulates Beclin-1 in hyperoxic acute lung injury.

表皮生长因子受体在高氧性急性肺损伤中调节Beclin-1。

Harris Zachary M, Korde Asawari, Khoury Johad, Manning Edward P, Stanley Gail, Shin Yosep, Mitchell Kennedy, von der Schulenburg Alexa, Sun Ying, Hu Buqu, Shin Hyeon Jun, Joerns John, Clark Brian, Placek Lindsey, Unutmaz Derya, Moldobaeva Aigul, Sharma Lokesh, Sauler Maor, Rajagopalan Govindarajan, Zhang Xuchen, Wang He, Ghaedi Mahboobe, Kang Min-Jong, Koff Jonathan L

NF-κB aggravates cardiac vascular endothelial injury by sustained activation of the NLRP3 inflammasome after ischemic stroke in rats.

NF-κB 通过持续激活 NLRP3 炎症小体,在大鼠缺血性中风后加剧心脏血管内皮损伤。

Zhong Shufeng, Xiao Yuan, Liu Junqiang

Polydatin Relieves Airway Remodeling by Inhibiting P2X7R-NLRP3-Mediated Excessive Autophagy in Asthma.

白藜芦醇苷通过抑制 P2X7R-NLRP3 介导的哮喘过度自噬来缓解气道重塑。

Li Guangxing, Li Liangchang, Wang Zhiguang, Piao Yihua, Song Yilan, Li Li, Xu Chang, Li Xiaowan, Yan Guanghai

Astragaloside IV inhibits MAPK pathway and promotes mitochondrial autophagy in rats with heart failure.

黄芪甲苷 IV 可抑制 MAPK 通路并促进心力衰竭大鼠的线粒体自噬。

Wang Yaoyao, Chen Yujiang, Li Tengxian, Zhong Peng, Wang Qinsha

Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy.

黄芪甲苷 IV 通过 DUSP1-Prohibitin 2 介导的线粒体质量控制和内质网自噬减轻脓毒症心肌损伤。

USP4-mediated CENPF deubiquitylation regulated tumor metastasis in colorectal cancer

USP4介导的CENPF去泛素化调控结直肠癌的肿瘤转移

Zhongdong Xie #, Hanbin Lin #, Yuecheng Wu #, Yanan Yu #, Xintong Liu #, Yating Zheng, Xiaojie Wang, Jiashu Wu, Meifang Xu, Yuting Han, Qiongying Zhang, Yu Deng, Lin Lin, Yan Linzhu, Li Qingyun, Xinjian Lin, Ying Huang, Pan Chi2
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