Anti-Ferritin heavy chain antibody [EPR3004Y] (Ab75973)

FTH, FTHL6, OK/SW-cl.84, PIG15, FTH1, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein

反应种属:Human, Mouse, Rat
抗原名称:FTH1
应用:WB, FCM, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

We recommend following our protocol when testing ICC and recommend using lower dilution in samples having low expression level of Ferritin.

背景信息

Product Specifications Anti-Ferritin heavy chain antibody [EPR3004Y] (ab75973) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, WB in human, mouse, rat samples. Anti-Ferritin heavy chain antibody [EPR3004Y] (ab75973) specifically detects Ferritin Heavy Chain (UniProt ID: P02794; Molecular weight: 21kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Ferritin heavy chain antibody [EPR3004Y] (ab75973) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Ferritin heavy chain antibody [EPR3004Y] (ab75973) has been confirmed by testing in knockout samples. Anti-Ferritin heavy chain antibody [EPR3004Y] (ab75973) has been cited over 113 times in peer reviewed journals and is trusted by the scientific community. Anti-Ferritin heavy chain antibody [EPR3004Y] (ab75973) has 7 independent reviews from customers. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (209)

Peritumoural adipose tissue promotes ferroptosis resistance by 3-hydroxykynurenine-mediated suppression of ferritinophagy.

肿瘤周围脂肪组织通过 3-羟基犬尿氨酸介导的抑制铁蛋白自噬来促进铁死亡抵抗。

Zhang Yan-Yu, Han Yi, Tan Yue-Tao, Lu Yun-Xin, Ma Meng-Yao, Zheng Yong-Qiang, Chen Hao-Jie, Fu Hai-Yan, Mo Hai-Yu, Wu Qi-Nian, Luo Xiao-Jing, Liao Kun, Chen Wen-Qi, Zeng Zhao-Lei, Piao Hai-Long, Du Hong-Li, Lin Jun-Zhong, Tian Tian, Xu Rui-Hua, Ju Huai-Qiang

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy.

TrxR2 乳酸化促进糖尿病心肌病中的线粒体保护和内皮细胞铁死亡抵抗。

Li Su, Liu Muyin, Chen Chao, Li Xinyan, Yan Xiaopei, Zhu Wentao, Qiu Wenyan, Li Qiyu, Sun Xiangyu, Huang Chao, Yin Ming, Chen Zhangwei, Lu Yao, Ge Junbo, Kong Xiangqing, Qian Juying, Chen Yuqiong

NCOA4-Mediated Ferritinophagy Induces Ferroptosis and Enriches Ferritin-Containing EVs via Ferritin Phase Separation to Promote Mechanical Ventilation-Induced Pulmonary Fibrosis.

NCOA4 介导的铁蛋白自噬诱导铁死亡,并通过铁蛋白相分离富集含铁蛋白的细胞外囊泡,从而促进机械通气诱导的肺纤维化。

Intravesical instillation of pirfenidone/polydopamine nanoparticles for managing neurogenic bladder post-spinal cord injury by alleviating bladder inflammation and fibrosis.

通过膀胱内灌注吡非尼酮/聚多巴胺纳米颗粒治疗脊髓损伤后神经源性膀胱,减轻膀胱炎症和纤维化。

Zhang Jizheng, Li Hui, Zhang Lekai, Lv Linchen, Zang Maolin, Wang Xinyv, Wang Shuai, Chen Lipeng, Yang Zizhuo, Yang Liang, Zhao Jianyou, Gao Xindong, Guo Dongyue, Shi Benkang, Zhang Zhiyue, Li Yan

Amino acid restriction sensitizes lung cancer cells to ferroptosis via GCN2-dependent activation of the integrated stress response.

氨基酸限制通过 GCN2 依赖性激活整合应激反应,使肺癌细胞对铁死亡更加敏感。

Targeting c-Myc-p300-CARM1 complex induces ferroptosis and reduces CD8(+) T cell exhaustion in esophageal squamous cell carcinoma.

靶向 c-Myc-p300-CARM1 复合物可诱导铁死亡并减少食管鳞状细胞癌中的 CD8(+) T 细胞耗竭。

Pregnancy precipitates metabolic imbalance and accelerates death in an animal model of mitochondrial cardiomyopathy.

在患有线粒体心肌病的动物模型中,妊娠会引发代谢失衡并加速死亡。

Sayles Nicole M, Casalena Gabriella, Zhao Dazhi, Dellinger Ryan W, Holmes Holly E, Manzo Onorina, Galkin Alexander, Di Lorenzo Annarita, Manfredi Giovanni

Retinoic Acid Alleviates TGEV-Induced Ferroptosis by Activating the p62-NRF2-GPX4/HO-1 Pathway and Iron Metabolism in Intestinal Epithelial Cells.

视黄酸通过激活肠上皮细胞中的 p62-NRF2-GPX4/HO-1 通路和铁代谢来缓解 TGEV 诱导的铁死亡。

Yin Conghui, Lai Xin, Pu Junning, Liu Chen, Luo Yuheng, He Jun, Yu Bing, Che Lianqiang, Wang Quyuan, Wang Huifen, Chen Daiwen, Wu Aimin

Safe dosage and potential risks of chlorogenic acid: insights from in vitro and in vivo studies.

绿原酸的安全剂量和潜在风险:来自体外和体内研究的见解。

Pang Yilin, Jiang Mengyao, Ge Binjie, Huang Lin, Rao Xiaoyu, Wang Xueqing, Zhou Huaibin, Lyu Jianxin, Wang Zheng, Tan Guoqiang

Pathological frataxin deficiency in mice causes tissue-specific alterations in iron homeostasis.

小鼠病理性弗拉塔辛缺乏会导致组织特异性的铁稳态改变。

Pazos-Gil Maria, Medina-Carbonero Marta, Sanz-Alcázar Arabela, Portillo-Carrasquer Marta, Oliveira-Jorge Luiza, Hernández Gonzalo, Sánchez Mayka, Delaspre Fabien, Cabiscol Elisa, Ros Joaquim, Tamarit Jordi
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 21