Anti-YB1 antibody [EP2708Y] (Ab76149)

NSEP1, YB1, YBX1, Y-box-binding protein 1, YB-1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Nuclease-sensitive element-binding protein 1, Y-box transcription factor, CBF-A, DBPB, EFI-A

反应种属:Human, Mouse, Rat
抗原名称:YBX1
应用:WB, IHC, FCM, IF/ICC, IP

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

What is this antibody validated in? Anti-YB1 antibody [EP2708Y] (ab76149) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of YB1? Anti-YB1 [EP2708Y] (ab76149) specifically detects a band for YB1 (UniProt: P67809) at a molecular weight of 36kDa. Trusted by the scientific community Anti-YB1 [EP2708Y] (ab76149) was first used in a scientific publication in 2009 and has been cited over 60 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EP2708Y] also available for your convenience: ab76149, HRP - ab204014, Carrier free - ab239875 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (89)

DUX4-induced HSATII RNA accumulation drives protein aggregation, impacting RNA processing pathways.

DUX4 诱导的 HSATII RNA 积累驱动蛋白质聚集,影响 RNA 加工途径。

Arends Tessa, Bennett Sean R, Tapscott Stephen J

The RNA methyltransferase NSUN2 catalyzes 5-methylcytosine (m(5)C) on IL1B mRNA to promote transcript stability.

RNA甲基转移酶NSUN2催化IL1B mRNA上的5-甲基胞嘧啶(m(5)C),以促进转录本的稳定性。

Wang Jiayun, Yan Lingyan, Jia Rong, Guo Jihua

NSUN2-engineered human umbilical cord mesenchymal stem cell-derived exosomes ameliorate tendon injury by promoting DNM2 expression.

NSUN2 工程化的人类脐带间充质干细胞衍生的外泌体通过促进 DNM2 表达来改善肌腱损伤。

Liu Yuxin, Pu Yalu, Li Qi, Yu Liang, Kou Hailong, Liu Yang, Shen Zhizhong, Zhao Yilei

NSUN2-mediated cytosine-5 methylation of FSP1 protects acute myeloid leukemia cells from ferroptosis

NSUN2介导的FSP1胞嘧啶-5甲基化可保护急性髓系白血病细胞免于铁死亡

Wenle Ye ,Yanchun Zhao ,Yutong Zhou ,Jiansong Huang ,Xiao He ,Zhixin Ma ,Xin Huang ,Chao Hu ,Fenglin Li ,Qing Ling ,Huafeng Wang ,Hongyan Tong ,Jie Sun ,Jie Jin

SMN deficiency inhibits endochondral ossification via promoting TRAF6-induced ubiquitination degradation of YBX1 in spinal muscular atrophy.

SMN 缺乏通过促进 TRAF6 诱导的 YBX1 泛素化降解来抑制脊髓性肌萎缩症中的软骨内成骨。

Zhou Zijie, Fan Xinbin, Xiang Taiyang, Suo Yinxuan, Shi Xiaoyan, Li Yaoyao, Hua Yimin, Sheng Lei, Zhou Xiaozhong

NSUN2 mediated-aberrant 5-methylcytosine methylation regulates autophagy-related ferroptosis in oral squamous cell carcinoma progression.

NSUN2 介导的异常 5-甲基胞嘧啶甲基化调节口腔鳞状细胞癌进展中的自噬相关铁死亡。

Lu Yunyang, Li Runze, Du Weidong, Wu Jie, He Yi, Yuan Lingyu, Chen Xun, Lv Shiyu, Shi Fangyang, Hu Jiajun, Zhao Wei, Yu Dongsheng

Targeting YBX1-m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma

靶向YBX1-m5C介导RNF115 mRNA环化和翻译,从而增强肝细胞癌中铁死亡的脆弱性

Ouwen Li,Ke An,Han Wang,Xianbin Li,Yueqin Wang,Lan Huang,Yue Du,Nuo Qin,Jiasheng Dong,Jingyao Wei,Ranran Sun,Yong Shi,Yanjia Guo,Xiangyi Sun,Ying Yang,Yun-Gui Yang,Quancheng Kan,Xin Tian

Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders.

对突触进行综合多组学表征,揭示了与神经发育障碍相关的 RNA 加工因子和泛素连接酶

Mei Yuan, Gosztyla Maya L, Tan Xinzhu, Dozier Lara E, Wilkinson Brent, McKetney Justin, Lee John, Chen Michael, Tsai Dorothy, Kopalle Hema, Gritsenko Marina A, Hartel Nicolas, Graham Nicholas A, Flores Ilse, Gilmore-Hall Stephen K, Xu Shuhao, Marquez Charlotte A, Liu Sophie N, Fong Dylan, Chen Jing, Licon Kate, Hong Derek, Wright Sarah N, Kreisberg Jason F, Nott Alexi, Smith Richard D, Qian Wei-Jun, Swaney Danielle L, Iakoucheva Lilia M, Krogan Nevan J, Patrick Gentry N, Zhou Yang, Feng Guoping, Coba Marcelo P, Yeo Gene W, Ideker Trey

The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting progenitor cell cycle progression.

m5C 阅读器 Ybx1 通过促进祖细胞周期进程来调节胚胎皮层神经发生

Zhang Jian, Che Pengfei, Yang Zhuoxuan, Zhang Pingrui, Shui Yuxuan, Lu Xibin, Xu Jiuzhou, She Yuanchu, Zhang Yanbo, Yu Jun, Ji Sheng-Jian

NSUN2 promotes colorectal cancer progression by stabilizing PHGDH mRNA to promote serine metabolism reprogramming.

NSUN2 通过稳定 PHGDH mRNA 促进丝氨酸代谢重编程,从而促进结直肠癌的进展

Li Hao, Gong Tingyue, Zhao Yongheng, Luo Yang, Tang Shuibin, Wang Tingfeng, Lin Haiping, Zhong Ming
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