Anti-STAT3 (phospho Y705) antibody [EP2147Y] (Ab76315)

APRF, STAT3, Signal transducer and activator of transcription 3, Acute-phase response factor

反应种属:Human, Mouse
抗原名称:STAT3 pY705
应用:WB, IHC, FCM, IF/ICC, IP, Dot

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

Product Specifications Anti-STAT3 (phospho Y705) antibody [EP2147Y] (ab76315) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Dot blot, ELISA, Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in human, mouse samples. Anti-STAT3 (phospho Y705) antibody [EP2147Y] (ab76315) specifically detects STAT3 Phospho-Y705 (UniProt ID: P40763; Molecular weight: 88kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-STAT3 (phospho Y705) antibody [EP2147Y] (ab76315) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-STAT3 (phospho Y705) antibody [EP2147Y] (ab76315) has been cited over 598 times in peer reviewed journals and is trusted by the scientific community. Anti-STAT3 (phospho Y705) antibody [EP2147Y] (ab76315) has 19 independent reviews from customers. Related Products Antibody clone EP2147Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 555 ( ab202876 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (661)

Tumour-infiltrating microplastics disrupt the JAK-STAT-microbiota axis to promote immunotherapy resistance in colorectal cancer.

肿瘤浸润性微塑料会破坏 JAK-STAT-微生物群轴,从而促进结直肠癌的免疫治疗耐药性。

Jiang Zhaohui, Liu Yongting, Zhang Peng, Fei Jiang, Wang Kailing, Li Yin, Zhang Xiangyang, Cai Changjing, Chen Yihong, Peng Yinghui, Shen Hong, Zeng Shan, Han Ying

A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.

通过 STAT3 磷酸化重编程线粒体代谢以促进骨骼再生的 DNA 四面体递送积雪草酸。

Huang Yiwen, Zhang Yiming, Feng Yisheng, Yang Qixiang, Gao Beiyuan, Xu Haiyang, Huang Cheng, Lin Kaili, Xu Yuanzhi, Zhu Peiqi

NGO ameliorates psoriasis by modulating mitochondrial function and suppressing pSTAT3-IL-17-expressing CD8(+) TRM cells.

NGO 通过调节线粒体功能和抑制表达 pSTAT3-IL-17 的 CD8(+) TRM 细胞来改善银屑病。

Kim Tae Ho, Lee Chae Rim, Choi Kyoung Min, Choi Soon Won, Lee Seon-Yeong, Lee A Ram, Choi Jung Won, Moon Young Mi, Park Joonhyuck, Choi Haeyoun, Ryu Jaechul, Bang Chul Hwan, Cho Mi-La

Methylated circPTK2 as a driver of fibroblast activation in pulmonary fibrosis.

甲基化的 circPTK2 是肺纤维化中成纤维细胞活化的驱动因素。

Zhu Yuguang, Zhao Lixin, Qin Jianfeng, Guo Bingpeng, Luo Xuedan, Feng Ziqi, Wei Juyan, Huang Xiaolong, Chen Xiying, Lin Yonghao, Yin Feng, Huang Yongyin, Zhang Yingyi, Wu Jiaxiang, Fang Junyan, Ding Shangwei, Zhang Yu, Li Yangxin, Han Qian, Shen Ao, Yu Xi-Yong

Loss of Frmd5 Inhibits Jak2-Stat3 Signalling Pathway and Impairs Cell Apoptosis During Vagina Luminal Formation in Puberty Mice.

Frmd5 的缺失抑制了 Jak2-Stat3 信号通路,并损害了青春期小鼠阴道腔形成过程中的细胞凋亡。

Su Tiantian, Wang Zhenbin, Wu Yunjiao, Li Qianchen, Tian Li, Li Xiaowei, Zhang Jing, Yu Miao, Xing Yuqi, Du Juan, Zhao Lijun, Zhan Jun, Zhang Hongquan

Abnormal mechanical load aggravates subchondral bone remodeling and uneven tibial plateau settlement in knee osteoarthritis via activation of osteoblast Piezo1-Ca²⁺-JAK2/STAT3 signaling

异常机械负荷通过激活成骨细胞 Piezo1-Ca²⁺-JAK2/STAT3 信号通路,加剧膝骨关节炎中的软骨下骨重塑和胫骨平台不均匀沉降。

Handi Li,Shuo Zhang,Chen Feng,Fangyan Cheng,Yuanyuan Han,Mengxue Wang,Shuai Zhou,Wenbo Shao,Wenzhong Chen,Jingguo Chen,Kai Liu,Yingze Zhang,Juan Wang

Targeting lactylation in a novel metabolic-epigenetic-inflammatory axis mitigates inflammation and promotes healing following corneal injury.

针对新型代谢-表观遗传-炎症轴中的乳酸化作用,可减轻炎症并促进角膜损伤后的愈合。

Guan Yi, Liu Jinghua, Liu Ying, Yan Yarong, Chao Zhengyu, Yan Xinlin, Lin Jiaqi, Huang Yulei, Zhu Jiahao, Yang Shumei, Jiang Li, Han Ruifang, Li Xuan

IL-33 released during liver resection facilitates intrahepatic cholangiocarcinoma growth via cytokine secretion in cancer-associated fibroblasts.

肝切除过程中释放的IL-33通过癌细胞相关成纤维细胞分泌细胞因子促进肝内胆管癌的生长。

Eguchi Satoshi, Yamada Daisaku, Kobayashi Shogo, Sasaki Kazuki, Iwagami Yoshifumi, Yamanaka Chihiro, Tomimaru Yoshito, Noda Takehiro, Sakaue Masaki, Asaoka Tadafumi, Shimizu Junzo, Takahashi Hidenori, Doki Yuichiro, Eguchi Hidetoshi

Inflammation-induced LncRNA SNHG1 orchestrates spermatogonium development in non-obstructive azoospermia via IL-17 A signaling pathway.

炎症诱导的 LncRNA SNHG1 通过 IL-17A 信号通路调控非梗阻性无精子症中的精原细胞发育。

Zhu Yongtong, Li Maocai, Zhan Xiaomin, Liu Li, Chen Cairong, Zhou Yao, He Pei, Hua Rui

Wilforine attenuates inflammatory osteolysis by suppressing osteoclast fusion through JAK-STAT-stomatin immunoregulatory signaling.

Wilforine 通过 JAK-STAT-stomatin 免疫调节信号抑制破骨细胞融合,从而减轻炎症性骨溶解。

Geng Shaohui, Guan Yiwei, Ye Zi, Zhao Dongdong, Jiang Yijin, Fu Jingyuan, Sheng Han, Yang Shuhan, Liu Hongxu, Deng Fuwen, Yu Shasha, Yimingjiang Mureziya, Wu Yuanhao, Li Chen, Huang Guangrui
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