Anti-CD81 antibody [M38] (Ab79559)

CD81, TAPA1, TSPAN28, CD81 antigen, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28

反应种属:Human
抗原名称:CD81
应用:WB, IHC, FCM

用户验证的应用

推荐稀释比例

  • IHC-P5 µg/mL Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • WB2 µg/mL
  • Flow Cyt1-4 µg/mL ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

详细信息

免疫原Cell preparation containing CD81 protein. The exact immunogen used to generate this antibody is proprietary information. P60033
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
全称Anti-CD81 antibody [M38]
产品形式Liquid
储存缓冲液pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
储存条件运输条件: Blue Ice 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

Product Specifications Anti-CD81 antibody [M38] (ab79559) is a mouse monoclonal antibody and is validated for use in Flow Cyt, IHC-P, WB in human samples. Anti-CD81 antibody [M38] (ab79559) specifically detects CD81 (UniProt ID: P60033; Molecular weight: 26kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CD81 antibody [M38] (ab79559) has high sensitivity and specificity. The specificity of Anti-CD81 antibody [M38] (ab79559) has been confirmed by testing in knockout samples. Anti-CD81 antibody [M38] (ab79559) has been cited over 142 times in peer reviewed journals and is trusted by the scientific community. Related Products Antibody clone M38 is also available pre-conjugated to a variety of labels for your convenience - APC/Cy7®, APC, Biotin, FITC, HRP ( ab200565, ab233259, ab239238, ab239256 ). Target Information CD81 or TAPA1 is a tetraspanin protein that plays a significant role in oncology, particularly in the context of cancer cell proliferation and metastasis. CD81 or TAPA1 is highly expressed in several types of cancer cells and it is involved in various cellular processes, including cell adhesion, migration, and signal transduction. CD81 also contributes to the tumor microenvironment by facilitating interactions between cancer cells and their surroundings.

文献引用 (225)

Engineered CAR-T-Derived Exosomes Co-Delivering miR-145 and Cytotoxic Proteins for Targeted Solid Tumour Therapy.

工程化 CAR-T 衍生外泌体共递送 miR-145 和细胞毒性蛋白用于靶向实体瘤治疗。

Yang Ruyue, Wang Haitao, Wang Guidan, Yuan Gankun, Wei Zhaoyi, An Junling, Hu Dong, Wen Wenjing, Gao Shegan, Wan Yuan, Liang Gaofeng

Activating the Osteoblastic USP26 Pathway Alleviates Multi-Organ Fibrosis by Decreasing Insulin Resistance.

激活成骨细胞 USP26 通路可通过降低胰岛素抵抗来缓解多器官纤维化。

Tang Jiyuan, Ye Wenkai, He Liang, Dan Zhou, Chang Leilei, You Zijie, Jiang Yuanyue, Tang Guoqing, Deng Lianfu, Li Changwei

Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors

可编程的iPSC衍生CAR-NK囊泡重塑免疫微环境并根除肿瘤

Hao Zhang,Shenglong Li,Chongzhong Liu,Xiangdong Gongye,Han Li,Yiyi Ji,Cheng-Wei Ju,Wenzhen Jia,Xing Niu,Yujing Guan,Xiangyu Zhai,Bin Jin,Peng Xia

Exosomal THBS4 Derived From Human Placental Mesenchymal Stem Cells Promotes the Migration and Angiogenesis of the Endothelial Cells in Preeclampsia by Activating the Integrin α2/PI3K/AKT Axis.

源自人胎盘间充质干细胞的外泌体 THBS4 通过激活整合素 α2/PI3K/AKT 轴促进先兆子痫内皮细胞的迁移和血管生成。

Yang Zejun, Liu Yu, Cui Jianjian, Chen Zhirui, Shi Haoran, Tao Hui, Ma Ruilin, He Wencong, Sun Lei, Li Yanan, Liu Ziyang, Wang Zetong, Zhao Yin

Acute myeloid leukemia (AML)-derived bone mesenchymal stem cell exosomal METTL14 promotes AML cell growth and glycolysis by HOXA3/WNT7B axis.

急性髓系白血病 (AML) 来源的骨髓间充质干细胞外泌体 METTL14 通过 HOXA3/WNT7B 轴促进 AML 细胞生长和糖酵解。

Liu Wanying, Ming Xi, Wu Jiaying, Yan Sijia, Su Shuai, Zheng Rubing, Wang Yu, Xiao Yi

ADSC-derived exosomes deliver cerium oxide nanoparticles to promote diabetic wound healing via anti-inflammatory and pro-angiogenic effects.

ADSC衍生的外泌体通过抗炎和促血管生成作用,将氧化铈纳米颗粒输送到糖尿病伤口,促进伤口愈合。

Zeng Yu, Huang Yichao, Li Qingyan, Zhang Yucheng, Yu Tao, Peng Tong, Nie Yuanpeng, Cao Leilei

Proteomic and Lipidomic Profiling of Immune Cell-Derived Subpopulations of Extracellular Vesicles.

免疫细胞来源的细胞外囊泡亚群的蛋白质组学和脂质组学分析。

Lischnig Anna, Karimi Nasibeh, Larsson Per, Ekström Karin, Crescitelli Rossella, Olin Anna-Carin, Lässer Cecilia

POSTN(+) fibroblast‑secreted small extracellular vesicles drive macrophage M2 polarization through BMP4/BMPR2/Smad signaling.

POSTN(+)成纤维细胞分泌的小细胞外囊泡通过BMP4/BMPR2/Smad信号传导驱动巨噬细胞M2极化。

SHED-Derived Exosomes Attenuate Osteoclastogenesis to Ameliorate Apical Periodontitis in Rats.

SHED来源的外泌体可减弱破骨细胞生成,从而改善大鼠根尖周炎。

Wang Siyu, Dai Zichao, Huo Lijun, Yang Rongqiang, Huang Guobin, Fang Hao, Chen Rui, Yang Hefeng, Wu Jinyan

Lung cancer screening based on plasma-derived exosomes via droplet coating deposition Raman spectroscopy and machine learning.

基于血浆衍生外泌体液滴涂层沉积拉曼光谱和机器学习的肺癌筛查。

Li Yuyi, Xiao Shuting, Huang Jing, Li Zongze, Pan Chunling, Dong Ming, Zhan Qiuqiang
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 23