Anti-MAP2 antibody - Neuronal Marker (Ab5392)

Microtubule-associated protein 2, MAP-2, MAP2

反应种属:Mouse, Rat
抗原名称:MAP2
应用:WB, IHC, IF/ICC

详细信息

免疫原Recombinant Fragment Protein within Human MAP2. The exact immunogen used to generate this antibody is proprietary information. P11137
宿主/亚型Chicken / IgY
抗体类型Polyclonal
产品形式Liquid
储存缓冲液Preservative: 0.032% Sodium azide Constituents: PBS
储存条件运输条件: Blue Ice 推荐的短期储存条件: +4°C 推荐的长期储存条件: +4°C 储存信息: Do Not Freeze

背景信息

Find all reagents to label mature neurons in our " Mature neuron markers guide ". Anti-MAP2 antibody (ab5392) is a chicken polyclonal antibody and is validated for use in ICC/IF, IHC-P and WB. Anti-MAP2 antibody (ab5392) was first used in a scientific publication in 2006 and has been cited over 788 times in peer reviewed journals. It's performance in IHC and Immunofluorescence in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-MAP2 antibody (ab5392) has high sensitivity and specificity. Anti-MAP2 antibody (ab5392) has 62 independent reviews from customers. Anti-MAP2 antibody (ab5392) specifically detects MAP2 (UniProt ID: P11137; Molecular weight: 200kDa) and is sold in 25 µL selling sizes. MAP2, a dendritic marker, plays a crucial role in Alzheimer's disease (AD) research. Researchers use MAP2 to assess dendritic integrity in AD models, making it essential for understanding neuronal structure and pathology in Alzheimer's disease.

文献引用 (1102)

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血清素系统靶向核酸水凝胶协调兴奋性恢复和回路重建,用于脊髓损伤治疗。

Li Chunlin, Zhao Xiaoqing, Jiang Kai, Kang Haixia, Liu Shuo, Jiang Linlin, Bai Baoshuai, Cui Haonan, Zhang Ziyang, Dong Menglei, Zhang Ruizhi, Zou Chenbo, Shang Shenghui, Zhang Chi, Fan Xiangchuang, Zhu Lijuan, Duan Huiquan, Zhang Chuan, Feng Shiqing, Zhou Hengxing

Distinct spatial patterning and transcriptomic landscapes of human neural organoids by localized delivery of morphogens.

通过局部递送形态发生素,实现人类神经类器官独特的空间模式和转录组景观。

Yang Feiyu, Pavon Narciso, Matsubara Tatsuya, Sebastian Rebecca, Martinez-Martin Beatriz, Pak ChangHui, Sun Yubing, Kim Deok-Ho

Functional implications of polygenic risk for schizophrenia in human neurons.

多基因风险对人类神经元中精神分裂症的功能影响。

Michael Deans P J, Retallick-Townsley Kayla G, Li Aiqun, Seah Carina, Johnson Jessica, Garcia Gonzalez Judit, Cao Evan, Schrode Nadine, Yu Alex, Cartwright Sam, Voloudakis Georgios, Zhang Wen, Wang Minghui, Fullard John F, Girdhar Kiran, Stahl Eli, Akbarian Schahram, Zhang Bin, Roussos Panos, O'Reilly Paul, Huckins Laura M, Brennand Kristen J

Quantitative optical nanoscopy of mitochondrial-derived vesicles in neurons classifies pre-peroxisomal and clearing organelles.

神经元中线粒体衍生囊泡的定量光学纳米显微镜技术可对过氧化物酶体前体和清除细胞器进行分类。

Coceano Giovanna, Alvelid Jonatan, Damenti Martina, Ferretti Gabriella, Mueller Johannes, Rorbach Joanna, Testa Ilaria

Brain and neural cell type proteomics reveal extracellular matrix proteins enriched in progressive multiple sclerosis.

脑和神经细胞类型蛋白质组学揭示了进行性多发性硬化症中富集的细胞外基质蛋白。

Wang Henry, Pollock Niall M, Miranzadeh Mahabadi Hajar, Patel Jainilkumar, Moussa Eman W, Fernandes Jason P, Branton William G, Zhang Na, Elliott Cameron, Schmitt Laura, Power Christopher, Julien Olivier

Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitro.

针对 KIF1A 多态性的反义寡核苷酸可以扩大靶点,并在体外挽救患者来源的神经元。

Zuccaro Michael V, Young Randee E, Hu Jiangyuan, Lanzano Patricia, Semenova Ekaterina, Lin Xiaoqi, Skowronski Alicja, Shen Yufeng, Kim Tae Hyun, Miller Danny E, Germain Noelle, Sarmiere Patrick, LeDuc Charles A, Chung Wendy K

Restoring early postnatal synaptic dysregulation rescues motor neuron degeneration in a mouse model of Spinal and Bulbar Muscular Atrophy.

恢复早期出生后突触功能障碍可以挽救脊髓延髓肌萎缩症小鼠模型中的运动神经元退化。

Hirunagi Tomoki, Sahashi Kentaro, Iida Madoka, Onodera Kazunari, Yokoi Satoshi, Ogura Yosuke, Tohnai Genki, Sakakibara Kenji, Maeda Kentaro, Bennett C Frank, Okada Yohei, Katsuno Masahisa

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia.

致病性 Tau 突变导致自噬溶酶体功能障碍,从而限制额颞叶痴呆模型中 Tau 的降解。

Mirfakhar Farzaneh S, Marsh Jacob A, Sato Chihiro, Schache Kylie J, Minaya Miguel A, Dolle Roland E, Pak Stephen C, Silverman Gary A, Perlmutter David H, Macauley Shannon L, Karch Celeste M

Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome.

唐氏综合征中突触和内在膜缺陷会破坏早期神经网络动力学。

Hannan Saad B, Alić Ivan, Murray Aoife, Kwon Joonhong, Mortensen Martin, Kang Hyo Jung, Plećaš Ante, Goh Pollyanna A, O'Brien Niamh L, Naud Richard, Nižetić Dean, Smart Trevor G

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair.

星形胶质细胞富集于三维皮质结构中可增强脑修复。

Cruz Elisa M, Soares Luana C, Greene Gretchen, Messore Fernando, Abuelem Mohammed, Li Mingyu, Andersen Caroline, Domocos Mirriam, Vitiello Elisa, Razak Rabeah Abdul, Lawston Marlene, Moser Gabriel, Vasaturo-Kolodner Talia, Barkat Mona, Bill Roslyn M, Mann Edward, Zhou Linna, Salman Mootaz M, Bayley Hagan, Molnár Zoltán, Szele Francis G
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